World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
37
Citations
5183
World Ranking
8821
National Ranking
520

Overview

Liang Zhang is affiliated with the University Health Network in Canada. Their research spans across neuroscience and medicine, with a particular focus on cellular and molecular neuroscience as well as molecular biology. Additional subfields relevant to their work include pulmonary and respiratory medicine, cognitive neuroscience, and neurology.

The primary research themes in Zhang's work cover neuroscience and neuropharmacology, neuroscience and neural engineering, prostate cancer diagnosis and treatment, neural dynamics and brain function, photoreceptor and optogenetics research, and epilepsy research and treatment.

Frequent collaborators include Peter L. Carlen, Haiyu Liu, D.A. Loblaw, Homeira Moradi Chameh, and Shreejoy J. Tripathy.

Zhang has contributed to multiple scientific journals, with numerous publications appearing in the International Journal of Radiation Oncology*Biology*Physics, bioRxiv (Cold Spring Harbor Laboratory), SSRN Electronic Journal, Nature Communications, and PubMed.

Recent published papers are as follows:

  • Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences, 2021, Nature Communications
  • Intraspecific recurrent selection in V. vinifera: an effective method for breeding of high quality, disease-, cold-, and drought -resistant grapes, 2021, Euphytica
  • Pannexin-1 Deficiency Decreases Epileptic Activity in Mice, 2020, International Journal of Molecular Sciences
  • Sexually dimorphic patterns in electroencephalography power spectrum and autism-related behaviors in a rat model of fragile X syndrome, 2020, Neurobiology of Disease
  • Computed Tomography-Based Radiomics Model for Predicting the WHO/ISUP Grade of Clear Cell Renal Cell Carcinoma Preoperatively: A Multicenter Study, 2021, Frontiers in Oncology

Best Publications

  • Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome.

    Yukiko Asaka;Denis G.M. Jugloff;Liang Zhang;James H. Eubanks

  • The role of gap junctions in seizures.

    Peter L Carlen;Frances Skinner;Liang Zhang;Christian Naus

  • Patch-clamp study of postnatal development of CA1 neurons in rat hippocampal slices: membrane excitability and K+ currents

    I. Spigelman;Liang Zhang;P. L. Carlen

  • Development of GABA‐mediated, chloride‐dependent inhibition in CA1 pyramidal neurones of immature rat hippocampal slices.

    L Zhang;I Spigelman;P L Carlen

  • The MeCP2-null mouse hippocampus displays altered basal inhibitory rhythms and is prone to hyperexcitability.

    Liang Zhang;Jiwei He;Denis G. M. Jugloff;Denis G. M. Jugloff;James H. Eubanks;James H. Eubanks

  • Changes in neuronal migration in neocortex of connexin43 null mutant mice.

    Shinji Fushiki;Jose Luis Perez Velazquez;Liang Zhang;John F. Bechberger

  • A fundamental oscillatory state of isolated rodent hippocampus.

    Chiping Wu;Chiping Wu;Hui Shen;Wah Ping Luk;Liang Zhang;Liang Zhang

  • Adenosine: a mediator of interleukin-1beta-induced hippocampal synaptic inhibition.

    Wah Ping Luk;Yu Zhang;Thomas D. White;Franklin A. Lue

  • Slow Oscillations (≤1 Hz) Mediated by GABAergic Interneuronal Networks in Rat Hippocampus

    Y. Zhang;J. L. Perez Velazquez;G. F. Tian;C.-P. Wu

  • Brief activation of GABAergic interneurons initiates the transition to ictal events through post-inhibitory rebound excitation.

    Michael Chang;Joshua A. Dian;Suzie Dufour;Lihua Wang

  • Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences

    Homeira Moradi Chameh;Scott Rich;Lihua Wang;Fu-Der Chen;Fu-Der Chen

  • Transient Global Ischemia Alters NMDA Receptor Expression in Rat Hippocampus: Correlation with Decreased Immunoreactive Protein Levels of the NR2A/2B Subunits, and an Altered NMDA Receptor Functionality

    L. Zhang;Jee Ching Hsu;N. Takagi;J. W. Gurd

  • Potentiation of a slow Ca(2+)-dependent K+ current by intracellular Ca2+ chelators in hippocampal CA1 neurons of rat brain slices.

    L. Zhang;P. Pennefather;A. Velumian;M. Tymianski

  • Transition to Seizure: Ictal Discharge Is Preceded by Exhausted Presynaptic GABA Release in the Hippocampal CA3 Region

    Zhang J. Zhang;Julius Koifman;Damian S. Shin;Hui Ye

  • Alterations of cortical and hippocampal EEG activity in MeCP2-deficient mice.

    Jennifer Anne D'Cruz;Jennifer Anne D'Cruz;Chiping Wu;Chiping Wu;Tariq Zahid;Tariq Zahid;Youssef El-Hayek;Youssef El-Hayek

  • Differential Modulation of Synaptic Transmission by Calcium Chelators in Young and Aged Hippocampal CA1 Neurons: Evidence for Altered Calcium Homeostasis in Aging

    Aviv Ouanounou;Liang Zhang;Milton P. Charlton;Milton P. Charlton;Peter L. Carlen

  • Model of frequent, recurrent, and spontaneous seizures in the intact mouse hippocampus

    M. Derchansky;E. Shahar;R.A. Wennberg;M. Samoilova

  • Hippocampal seizures alter the expression of the pannexin and connexin transcriptome

    Shanthini Mylvaganam;Liang Zhang;Liang Zhang;Chiping Wu;Zhang Jane Zhang;Zhang Jane Zhang

  • High frequency stimulation or elevated K+ depresses neuronal activity in the rat entopeduncular nucleus.

    D.S. Shin;M. Samoilova;M. Cotic;L. Zhang

  • Size does matter: generation of intrinsic network rhythms in thick mouse hippocampal slices.

    Chiping Wu;Wah Ping Luk;Jesse Gillis;Frances Skinner

  • Decreased Expression and Functionality of NMDA Receptor Complexes Persist in the CA1, but Not in the Dentate Gyrus after Transient Cerebral Ischemia:

    Jee Ching Hsu;Yu Zhang;Norio Takagi;James W. Gurd

Frequent Co-Authors

Peter L. Carlen
Peter L. Carlen University Health Network
James H. Eubanks
James H. Eubanks University Health Network
Milton P. Charlton
Milton P. Charlton University of Toronto
Richard Wennberg
Richard Wennberg University Health Network
Jose Luis Perez Velazquez
Jose Luis Perez Velazquez University of Toronto
Igor Spigelman
Igor Spigelman University of California, Los Angeles
W. McIntyre Burnham
W. McIntyre Burnham University of Toronto
Michael Tymianski
Michael Tymianski University Health Network
Peter C. Kind
Peter C. Kind University of Edinburgh
David R. Hampson
David R. Hampson University of Toronto

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