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Chemistry

D-Index
42
Citations
7209
World Ranking
17469
National Ranking
4281

Overview

Keykavous Parang is affiliated with Chapman University in the United States and has a research profile focused on biochemistry, genetics, and molecular biology, with significant contributions to medicine. Their scholarly work spans multiple subfields including molecular biology, organic chemistry, microbiology, oncology, and infectious diseases.

The researcher's work addresses several specialized topics, notably RNA interference and gene delivery, antimicrobial peptides and activities, advanced biosensing and bioanalysis techniques, chemical synthesis and analysis, click chemistry and applications, microRNA in disease regulation, and antimicrobial agents and applications.

Keykavous Parang has published extensively in various scientific journals. The frequent publication venues include:

  • Molecules
  • Preprints.org
  • Pharmaceutics
  • Journal of Medicinal Chemistry
  • Pharmaceuticals

Some of the recent papers authored or coauthored by Keykavous Parang are:

  • "A Global Review on Short Peptides: Frontiers and Perspectives," 2021, Molecules
  • "Cyclic Dipeptides: The Biological and Structural Landscape with Special Focus on the Anti-Cancer Proline-Based Scaffold," 2021, Biomolecules
  • "Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration," 2021, Proceedings of the National Academy of Sciences
  • "Comparative Antiviral Activity of Remdesivir and Anti-HIV Nucleoside Analogs against Human Coronavirus 229E (HCoV-229E)," 2020, Molecules
  • "Membrane-Active Cyclic Amphiphilic Peptides: Broad-Spectrum Antibacterial Activity Alone and in Combination with Antibiotics," 2022, Journal of Medicinal Chemistry

Keykavous Parang frequently collaborates with other researchers in the field. The principal coauthors include:

  • Rakesh Kumar Tiwari
  • Sandeep Lohan
  • Eman H. M. Mohammed
  • Saghar Mozaffari
  • Dindyal Mandal

Their research contributions demonstrate ongoing involvement in both fundamental and applied aspects of molecular biology and medicinal chemistry. The combination of work on peptides, nucleic acids, and bioactive molecules reflects a multidisciplinary approach aimed at addressing issues related to infectious diseases, cancer, and biochemical mechanisms.

Best Publications

  • Self-assembly of peptides to nanostructures

    Dindyal Mandal;Amir Nasrolahi Shirazi;Keykavous Parang

  • Mechanism-based design of a protein kinase inhibitor.

    Keykavous Parang;Jeffrey H. Till;Ararat J. Ablooglu;Ronald A. Kohanski

  • Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event.

    Rashna Bhandari;Adolfo Saiardi;Yousef Ahmadibeni;Adele M. Snowman

  • Cell-penetrating homochiral cyclic peptides as nuclear-targeting molecular transporters.

    Deendayal Mandal;Amir Nasrolahi Shirazi;Keykavous Parang

  • Novel Approaches for Designing 5'-O-Ester Prodrugs of 3'-Azido-2'3'-Dideoxythymidine (AZT)

    Keykavous Parang;Leonard I. Wiebe;Edward E. Knaus

  • Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome

    Cong Cao;Mengia S. Rioult-Pedotti;Paolo Migani;Crystal J. Yu

  • Inhibitors of Protein Kinase Signaling Pathways Emerging Therapies for Cardiovascular Disease

    Thomas Force;Keisuke Kuida;Mark Namchuk;Keykavous Parang

  • Current Targets for Anticancer Drug Discovery

    Nguyen Hai Nam;Keykavous Parang

  • Designing bisubstrate analog inhibitors for protein kinases

    Keykavous Parang;Philip A Cole

  • Design and biological evaluation of cell-penetrating peptide-doxorubicin conjugates as prodrugs.

    Amir Nasrolahi Shirazi;Rakesh Tiwari;Bhupender S. Chhikara;Dindyal Mandal

  • Development of cytarabine prodrugs and delivery systems for leukemia treatment

    Bhupender S Chhikara;Keykavous Parang

  • Synthesis of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates and evaluation of their Src kinase inhibitory and anticancer activities

    Anil Kumar;Anil Kumar;Israr Ahmad;Bhupender S. Chhikara;Rakesh Tiwari

  • A review (Research and Patents) on jasmonic acid and its derivatives

    Abdollah Ghasemi Pirbalouti;Abdollah Ghasemi Pirbalouti;Seyed Ebrahim Sajjadi;Keykavous Parang

  • Fatty acyl amide derivatives of doxorubicin: synthesis and in vitro anticancer activities.

    Bhupender S. Chhikara;Nicole St. Jean;Deendayal Mandal;Anil Kumar

  • Determination of the substrate-docking site of protein tyrosine kinase C-terminal Src kinase.

    Sungsoo Lee;Xiaofeng Lin;Nguyen Hai Nam;Keykavous Parang

  • Cyclic Dipeptides: The Biological and Structural Landscape with Special Focus on the Anti-Cancer Proline-Based Scaffold

    Joanna Bojarska;Adam Mieczkowski;Zyta M. Ziora;Mariusz Skwarczynski

  • Synthesis, Anticancer Activities, and Cellular Uptake Studies of Lipophilic Derivatives of Doxorubicin Succinate

    Bhupender S. Chhikara;Deendayal Mandal;Keykavous Parang

  • 3-substitued indoles: one-pot synthesis and evaluation of anticancer and Src kinase inhibitory activities.

    V. Kameshwara Rao;Bhupender S. Chhikara;Amir Nasrolahi Shirazi;Rakesh Tiwari

  • Enhanced Cellular Uptake of Short Polyarginine Peptides through Fatty Acylation and Cyclization

    Donghoon Oh;Amir Nasrolahi Shirazi;Amir Nasrolahi Shirazi;Kevin Northup;Brian Sullivan

  • Cyclic peptide-capped gold nanoparticles as drug delivery systems

    Amir Nasrolahi Shirazi;Dindyal Mandal;Rakesh K. Tiwari;Liangran Guo

  • Synthesis and Antifungal Activities of Myristic Acid Analogs

    Keykavous Parang;Edward E. Knaus;Leonard I. Wiebe;Soroush Sardari

  • Thiazolyl N-benzyl-substituted acetamide derivatives: synthesis, Src kinase inhibitory and anticancer activities.

    Asal Fallah-Tafti;Alireza Foroumadi;Rakesh Tiwari;Amir Nasrolahi Shirazi

Frequent Co-Authors

Philip A. Cole
Philip A. Cole Brigham and Women's Hospital
Akhilesh K. Verma
Akhilesh K. Verma University of Delhi
Alireza Foroumadi
Alireza Foroumadi Tehran University of Medical Sciences
Anil Kumar
Anil Kumar Indian Institute of Information Technology Design and Manufacturing Jabalpur
Abdollah Ghasemi Pirbalouti
Abdollah Ghasemi Pirbalouti Islamic Azad University, Tehran
Stevan R. Hubbard
Stevan R. Hubbard New York University
Navindra P. Seeram
Navindra P. Seeram University of Rhode Island
Virinder S. Parmar
Virinder S. Parmar City University of New York
Istvan Toth
Istvan Toth University of Queensland
Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine

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