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D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
28573
World Ranking
6145
National Ranking
2885

Overview

Laura Pasqualucci is affiliated with Columbia University in the United States. Their research primarily focuses on medicine, with significant contributions in biochemistry, genetics, molecular biology, immunology, and microbiology. The scientific work crosses several key subfields including immunology, molecular biology, pathology and forensic medicine, oncology, and genetics.

Their research topics emphasize lymphoma diagnosis and treatment, immune cell function and interaction, T-cell and B-cell immunology, CAR-T cell therapy research, chronic lymphocytic leukemia research, cancer-related gene regulation, and viral-associated cancers and disorders.

Laura Pasqualucci has published extensively in multiple scientific venues. The most frequent publication venues include:

  • Hematological Oncology
  • Blood
  • Blood Cancer Discovery
  • Proceedings of the National Academy of Sciences
  • Nature

Several recent papers highlight the scope and impact of their work:

  • "Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome" (2020, The Journal of Experimental Medicine)
  • "Genomic profiling for clinical decision making in lymphoid neoplasms" (2022, Blood)
  • "Super-enhancer hypermutation alters oncogene expression in B cell lymphoma" (2022, Nature)
  • "Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization" (2020, Cancer Discovery)
  • "Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma" (2021, Proceedings of the National Academy of Sciences)

The scientist collaborates frequently with several coauthors. Notable frequent collaborators include:

  • Riccardo Dalla-Favera
  • Katia Basso
  • Antony B. Holmes
  • Clarissa Corinaldesi
  • Rahul Kumar

Best Publications

  • Cytoplasmic Nucleophosmin in Acute Myelogenous Leukemia with a Normal Karyotype

    Brunangelo Falini;Christina Mecucci;Enrico Tiacci;Myriam Alcalay

  • Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

    Martin Peifer;Lynnette Fernández-Cuesta;Martin L. Sos;Julie George

  • Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

    Laura Pasqualucci;Peter Neumeister;Tina Goossens;Gouri Nanjangud

  • Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

    Mara Compagno;Wei Keat Lim;Adina Grunn;Subhadra V. Nandula

  • BRAF mutations in hairy-cell leukemia

    Enrico Tiacci;Vladimir Trifonov;Gianluca Schiavoni;Antony Holmes

  • Analysis of the coding genome of diffuse large B-cell lymphoma

    Laura Pasqualucci;Vladimir Trifonov;Giulia Fabbri;Jing Ma

  • Inactivating mutations of acetyltransferase genes in B-cell lymphoma

    Laura Pasqualucci;David Dominguez-Sola;Annalisa Chiarenza;Giulia Fabbri

  • Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

    Stefano Monti;Kerry J. Savage;Jeffery L. Kutok;Friedrich Feuerhake

  • Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation

    Giulia Fabbri;Silvia Rasi;Davide Rossi;Vladimir A. Trifonov

  • BCL-6 mutations in normal germinal center B cells: Evidence of somatic hypermutation acting outside Ig loci

    Laura Pasqualucci;Anna Migliazza;Nicola Fracchiolla;Christopher William

  • Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

    Davide Rossi;Silvia Rasi;Valeria Spina;Alessio Bruscaggin

  • Genetics of Follicular Lymphoma Transformation

    Laura Pasqualucci;Hossein Khiabanian;Marco Fangazio;Mansi Vasishtha

  • Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia

    Davide Rossi;Silvia Rasi;Giulia Fabbri;Valeria Spina

  • Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

    Laura Pasqualucci;Mara Compagno;Jane Houldsworth;Stefano Monti

  • Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness.

    Davide Rossi;Alessio Bruscaggin;Valeria Spina;Silvia Rasi

  • Combined Genetic Inactivation of β2-Microglobulin and CD58 Reveals Frequent Escape from Immune Recognition in Diffuse Large B Cell Lymphoma

    Madhavi Challa-Malladi;Yen K. Lieu;Olivia Califano;Antony B. Holmes

  • AID is required for germinal center-derived lymphomagenesis.

    Laura Pasqualucci;Govind Bhagat;Mila Jankovic;Mara Compagno

  • A Signaling Pathway Mediating Downregulation of BCL6 in Germinal Center B Cells Is Blocked by BCL6 Gene Alterations in B Cell Lymphoma

    Masumichi Saito;Jie Gao;Katia Basso;Yukiko Kitagawa

  • Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice

    Giorgio Cattoretti;Laura Pasqualucci;Gianna Ballon;Wayne Tam

  • Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis

    Jiyuan Zhang;David Dominguez-Sola;David Dominguez-Sola;Shafinaz Hussein;Ji-Eun Lee

Frequent Co-Authors

Riccardo Dalla-Favera
Riccardo Dalla-Favera Columbia University
Raul Rabadan
Raul Rabadan Columbia University
Gianluca Gaidano
Gianluca Gaidano University of Eastern Piedmont Amadeo Avogadro
Davide Rossi
Davide Rossi European Society for Medical Oncology
Brunangelo Falini
Brunangelo Falini University of Perugia
Govind Bhagat
Govind Bhagat Columbia University
Robin Foà
Robin Foà Sapienza University of Rome
Francesco Bertoni
Francesco Bertoni Institute of Oncology Research
Giorgio Inghirami
Giorgio Inghirami Cornell University
Daniela Capello
Daniela Capello University of Eastern Piedmont Amadeo Avogadro

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