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Faustino Mollinedo

Faustino Mollinedo

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Biology and Biochemistry
Spain
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
44217
World Ranking
5785
National Ranking
85

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Spain Leader Award

Overview

Faustino Mollinedo is affiliated with the University of Salamanca in Spain, contributing extensively to the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their research encompasses numerous subfields including Molecular Biology, Organic Chemistry, Cell Biology, Epidemiology, and Immunology.

The scientist's work addresses several main topics, such as:

  • Autophagy in Disease and Therapy
  • Lipid Membrane Structure and Behavior
  • Endoplasmic Reticulum Stress and Disease
  • Synthesis and biological activity
  • Caveolin-1 and cellular processes
  • Pancreatic function and diabetes
  • Sphingolipid Metabolism and Signaling

Mollinedo has published research in various scientific journals, with frequent appearances in the following publication venues:

  • Cancers
  • Biomedicine & Pharmacotherapy
  • European Journal of Medicinal Chemistry
  • Journal of Lipid Research
  • Scientific Reports

Selected recent papers authored or co-authored by Mollinedo include:

  • Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy, 2020, Journal of Lipid Research
  • Direct Endoplasmic Reticulum Targeting by the Selective Alkylphospholipid Analog and Antitumor Ether Lipid Edelfosine as a Therapeutic Approach in Pancreatic Cancer, 2021, Cancers

Additional notable papers related to their collaborative research network include:

  • Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release, 2021, Scientific Reports
  • First and Second Waves of Coronavirus Disease 2019 in Madrid, Spain: Clinical Characteristics and Hematological Risk Factors Associated With Critical/Fatal Illness, 2021, Critical Care Explorations
  • Upregulated expression and function of the α4β1 integrin in multiple myeloma cells resistant to bortezomib, 2020, The Journal of Pathology

Throughout their career, Mollinedo has collaborated frequently with other researchers. Notable frequent co-authors include:

  • Consuelo Gajate
  • Alba Vicente-Blázquez
  • Manuel Medarde
  • Rafael Peláez
  • Raquel Álvarez

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Microtubules, microtubule-interfering agents and apoptosis

    Faustino Mollinedo;Consuelo Gajate

  • Arginase I is constitutively expressed in human granulocytes and participates in fungicidal activity.

    Markus Munder;Faustino Mollinedo;Jero Calafat;Javier Canchado

  • Intracellular Alkalinization Suppresses Lovastatin-induced Apoptosis in HL-60 Cells through the Inactivation of a pH-dependent Endonuclease (∗)

    Dolores Pérez-Sala;Dolores Collado-Escobar;Faustino Mollinedo

  • The antitumor ether lipid ET-18-OCH3 induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells

    Consuelo Gajate;Faustino Mollinedo

  • Lipid rafts as major platforms for signaling regulation in cancer

    Faustino Mollinedo;Consuelo Gajate

  • Neutrophil Degranulation, Plasticity, and Cancer Metastasis.

    Faustino Mollinedo

  • Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts

    Consuelo Gajate;Faustino Mollinedo

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Granulocyte macrophage-colony stimulating factor stimulates both association and activation of phosphoinositide 3OH-kinase and src-related tyrosine kinase(s) in human myeloid derived cells.

    S. Corey;A. Eguinoa;K. Puyana-Theall;J.B. Bolen

  • Selective Induction of Apoptosis in Cancer Cells by the Ether Lipid ET-18-OCH3 (Edelfosine): Molecular Structure Requirements, Cellular Uptake, and Protection by Bcl-2 and Bcl-XL

    Faustino Mollinedo;Jose Luis Fernández-Luna;Consuelo Gajate;Belén Martín-Martín

  • Intracellular Triggering of Fas Aggregation and Recruitment of Apoptotic Molecules into Fas-enriched Rafts in Selective Tumor Cell Apoptosis

    Consuelo Gajate;Esther del Canto-Jañez;A. Ulises Acuña;Francisco Amat-Guerri

  • Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy.

    Consuelo Gajate;Faustino Mollinedo

  • Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH(3) (edelfosine), a proapoptotic agent in tumor cells.

    Consuelo Gajate;Faustino Mollinedo

  • Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy: Thematic Review Series: Biology of Lipid Rafts.

    Faustino Mollinedo;Consuelo Gajate

  • Prevention of in vitro neutrophil-endothelial attachment through shedding of L-selectin by nonsteroidal antiinflammatory drugs

    F Díaz-González;I González-Alvaro;M R Campanero;F Mollinedo

  • Fas/CD95 death receptor and lipid rafts: new targets for apoptosis-directed cancer therapy.

    Faustino Mollinedo;Consuelo Gajate

Frequent Co-Authors

Consuelo Gajate
Consuelo Gajate Spanish National Research Council
Pedro A. Lazo
Pedro A. Lazo University of Salamanca
Francisco Sánchez-Madrid
Francisco Sánchez-Madrid Autonomous University of Madrid
Jesús Balsinde
Jesús Balsinde Spanish National Research Council
Manuel Modolell
Manuel Modolell Max Planck Society
Sergio Lavandero
Sergio Lavandero University of Chile
Evelina Gatti
Evelina Gatti Aix-Marseille University
Steven Finkbeiner
Steven Finkbeiner University of California, San Francisco
Dolores Pérez-Sala
Dolores Pérez-Sala Spanish National Research Council
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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