World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
8213
World Ranking
17289
National Ranking
393

Overview

Consuelo Gajate is affiliated with the Spanish National Research Council in Spain. Their research primarily focuses on the interface of biochemistry, genetics, molecular biology, and medicine, with a significant contribution to the understanding of molecular and cell biology.

The scientist has contributed notably to several specialized research topics, including:

  • Autophagy in Disease and Therapy
  • Lipid Membrane Structure and Behavior
  • Endoplasmic Reticulum Stress and Disease
  • Pancreatic Function and Diabetes
  • Sphingolipid Metabolism and Signaling
  • Synthesis and Biological Activity
  • RNA Interference and Gene Delivery

Consuelo Gajate's publication record includes work published in journals such as Cancers, Biomedicine & Pharmacotherapy, European Journal of Medicinal Chemistry, Journal of Lipid Research, and Scientific Reports. Their contributions cover molecular mechanisms and cell signaling pathways relevant to cancer biology and therapeutic approaches.

Some of the recent papers authored by or including Consuelo Gajate are:

  • Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy, 2020, Journal of Lipid Research
  • Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release, 2021, Scientific Reports
  • Direct Endoplasmic Reticulum Targeting by the Selective Alkylphospholipid Analog and Antitumor Ether Lipid Edelfosine as a Therapeutic Approach in Pancreatic Cancer, 2021, Cancers
  • Upregulated expression and function of the α4β1 integrin in multiple myeloma cells resistant to bortezomib, 2020, The Journal of Pathology
  • Mitochondrial Targeting Involving Cholesterol-Rich Lipid Rafts in the Mechanism of Action of the Antitumor Ether Lipid and Alkylphospholipid Analog Edelfosine, 2021, Pharmaceutics

Frequent collaborators in research include Faustino Mollinedo, Alba Vicente-Blázquez, Raquel Álvarez, Laura Aramburu, and Manuel Medarde. Among these, Faustino Mollinedo stands out as a primary coauthor with multiple publications together.

The publication venues where Consuelo Gajate most often publishes include:

  • Cancers
  • Biomedicine & Pharmacotherapy
  • European Journal of Medicinal Chemistry
  • Journal of Lipid Research
  • Scientific Reports

Their work spans several subfields, with a concentration in molecular biology, cell biology, epidemiology, organic chemistry, and immunology.

Consuelo Gajate's research addresses important molecular pathways in cancer, particularly mechanisms related to lipid rafts, endoplasmic reticulum stress, and the biological behavior of cancer cells under therapeutic stress. This research has implications for the understanding and treatment of cancer progression, multiple myeloma, and pancreatic cancer.

Best Publications

  • Microtubules, microtubule-interfering agents and apoptosis

    Faustino Mollinedo;Consuelo Gajate

  • The antitumor ether lipid ET-18-OCH3 induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells

    Consuelo Gajate;Faustino Mollinedo

  • Lipid rafts as major platforms for signaling regulation in cancer

    Faustino Mollinedo;Consuelo Gajate

  • Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts

    Consuelo Gajate;Faustino Mollinedo

  • Selective Induction of Apoptosis in Cancer Cells by the Ether Lipid ET-18-OCH3 (Edelfosine): Molecular Structure Requirements, Cellular Uptake, and Protection by Bcl-2 and Bcl-XL

    Faustino Mollinedo;Jose Luis Fernández-Luna;Consuelo Gajate;Belén Martín-Martín

  • Intracellular Triggering of Fas Aggregation and Recruitment of Apoptotic Molecules into Fas-enriched Rafts in Selective Tumor Cell Apoptosis

    Consuelo Gajate;Esther del Canto-Jañez;A. Ulises Acuña;Francisco Amat-Guerri

  • Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy.

    Consuelo Gajate;Faustino Mollinedo

  • Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH(3) (edelfosine), a proapoptotic agent in tumor cells.

    Consuelo Gajate;Faustino Mollinedo

  • Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy: Thematic Review Series: Biology of Lipid Rafts.

    Faustino Mollinedo;Consuelo Gajate

  • Fas/CD95 death receptor and lipid rafts: new targets for apoptosis-directed cancer therapy.

    Faustino Mollinedo;Consuelo Gajate

  • Selective induction of apoptosis by capsaicin in transformed cells: the role of reactive oxygen species and calcium.

    Antonio Macho;Marco A Calzado;Juan Muñoz-Blanco;Consuelo Gómez-Díaz

  • Intracellular triggering of Fas, independently of FasL, as a new mechanism of antitumor ether lipid-induced apoptosis.

    Consuelo Gajate;Rosalba I. Fonteriz;Christelle Cabaner;Christelle Cabaner;Granada Alvarez-Noves

  • Major co-localization of the extracellular-matrix degradative enzymes heparanase and gelatinase in tertiary granules of human neutrophils.

    Faustino Mollinedo;Motowo Nakajima;Ana Llorens;Enrique Barbosa

  • ET-18-OCH3 (edelfosine): a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptor.

    Faustino Mollinedo;Consuelo Gajate;Sonsoles Martin-Santamaria;Federico Gago

  • Involvement of mitochondria and caspase‐3 in ET‐18‐OCH3‐induced apoptosis of human leukemic cells

    Gajate C;Santos-Beneit Am;Santos-Beneit Am;Macho A;Lazaro

  • Lipid raft-targeted therapy in multiple myeloma

    F Mollinedo;J de la Iglesia-Vicente;C Gajate;A Estella-Hermoso de Mendoza

  • Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety.

    Ana B S Maya;Concepción Pérez-Melero;Carmen Mateo;Dulce Alonso

  • Combinatorial SNARE Complexes Modulate the Secretion of Cytoplasmic Granules in Human Neutrophils

    Faustino Mollinedo;Jero Calafat;Hans Janssen;Belén Martín-Martín

  • Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells.

    Consuelo Gajate;Fernando Gonzalez-Camacho;Faustino Mollinedo

  • Lipid raft connection between extrinsic and intrinsic apoptotic pathways

    Consuelo Gajate;Fernando Gonzalez-Camacho;Faustino Mollinedo

Frequent Co-Authors

Faustino Mollinedo
Faustino Mollinedo University of Salamanca
Manuel Modolell
Manuel Modolell Max Planck Society
Francisco Amat-Guerri
Francisco Amat-Guerri Spanish National Research Council
Eduardo Muñoz
Eduardo Muñoz University of Córdoba
Paulo J. Oliveira
Paulo J. Oliveira University of Coimbra
Juan C. Gómez-Fernández
Juan C. Gómez-Fernández University of Murcia
María L. López-Rodríguez
María L. López-Rodríguez Complutense University of Madrid
Valentín Ceña
Valentín Ceña University of Castilla-La Mancha
Atanasio Pandiella
Atanasio Pandiella Spanish National Research Council
Constantine S. Mitsiades
Constantine S. Mitsiades Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry opens doors to a range of online degree options and specialized career paths. Students seeking a fast-track route can opt for an accelerated biology degree. These programs allow you to complete your studies more quickly, helping you enter the workforce or continue your education sooner.

For those interested in healthcare, an online asn degree provides a flexible way to start a nursing career. Nutritional science is another growing field, and earning one of the best online nutrition programs offers opportunities in wellness, dietetics, and community health.

If you're considering management roles in healthcare, pursuing one of the top cahme accredited mha programs can set you up for leadership positions in hospitals and healthcare organizations. These diverse online paths help biology and biochemistry students tailor their education to fit their career goals, all while enjoying the convenience of remote study.

Best Scientists Citing Consuelo Gajate

Trending Scientists

Recently Published Articles