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Toru Komatsu

Toru Komatsu

D-Index & Metrics

Chemistry

D-Index
46
Citations
7168
World Ranking
16110
National Ranking
1271

Overview

Toru Komatsu is affiliated with the University of Tokyo in Japan and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research encompasses a range of subfields including molecular biology, oncology, organic chemistry, materials chemistry, and biomedical engineering.

The scientific work of Toru Komatsu frequently addresses specific topics such as peptidase inhibition and analysis, click chemistry and applications, nanoplatforms for cancer theranostics, advanced biosensing and bioanalysis techniques, protein degradation and inhibitors, cancer, hypoxia, and metabolism, as well as luminescence and fluorescent materials.

Several recent papers illustrate Komatsu's involvement in these areas. Key publications include:

  • General Design Strategy to Precisely Control the Emission of Fluorophores via a Twisted Intramolecular Charge Transfer (TICT) Process, 2022, Journal of the American Chemical Society
  • A Fluorescent Probe for Rapid, High-Contrast Visualization of Folate-Receptor-Expressing Tumors In Vivo, 2020, Angewandte Chemie International Edition
  • Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples, 2020, Science Advances
  • Design of spontaneously blinking fluorophores for live-cell super-resolution imaging based on quantum-chemical calculations, 2020, Chemical Communications
  • Covalent Self-Labeling of Tagged Proteins with Chemical Fluorescent Dyes in BY-2 Cells and Arabidopsis Seedlings, 2020, The Plant Cell

Komatsu has published frequently in venues such as:

  • Journal of the American Chemical Society
  • Science Advances
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Chemical Science
  • Scientific Reports

The scientist has collaborated extensively with other researchers. Frequent co-authors include Yasuteru Urano, Kenjiro Hanaoka, Tasuku Ueno, Tetsuo Nagano, and Takayuki Ikeno.

Best Publications

  • Development of a highly selective fluorescence probe for hydrogen sulfide.

    Kiyoshi Sasakura;Kenjiro Hanaoka;Norihiro Shibuya;Yoshinori Mikami

  • Development of a highly sensitive fluorescence probe for hydrogen peroxide.

    Masahiro Abo;Yasuteru Urano;Kenjiro Hanaoka;Takuya Terai

  • Development of azo-based fluorescent probes to detect different levels of hypoxia.

    Wen Piao;Satoru Tsuda;Yuji Tanaka;Satoshi Maeda

  • Development of an Azo-Based Photosensitizer Activated under Mild Hypoxia for Photodynamic Therapy

    Wen Piao;Kenjiro Hanaoka;Tomotsumi Fujisawa;Satoshi Takeuchi

  • Development of a Far-Red to Near-Infrared Fluorescence Probe for Calcium Ion and its Application to Multicolor Neuronal Imaging

    Takahiro Egawa;Kenjiro Hanaoka;Yuichiro Koide;Sakiko Ujita

  • A reversible near-infrared fluorescence probe for reactive oxygen species based on Te–rhodamine

    Yuichiro Koide;Mitsuyasu Kawaguchi;Yasuteru Urano;Kenjiro Hanaoka

  • Development of a fluorescein analogue, TokyoMagenta, as a novel scaffold for fluorescence probes in red region

    Takahiro Egawa;Yuichiro Koide;Kenjiro Hanaoka;Toru Komatsu

  • Organelle-Specific, Rapid Induction of Molecular Activities and Membrane Tethering

    Toru Komatsu;Igor Kukelyansky;J Michael McCaffery;Tasuku Ueno

  • General Design Strategy to Precisely Control the Emission of Fluorophores via a Twisted Intramolecular Charge Transfer (TICT) Process.

    Unknown

  • Design and synthesis of highly sensitive fluorogenic substrates for glutathione S-transferase and application for activity imaging in living cells.

    Yuuta Fujikawa;Yasuteru Urano;Toru Komatsu;Kenjiro Hanaoka

  • An Activatable Photosensitizer Targeted to γ-Glutamyltranspeptidase.

    Mayumi Chiba;Yuki Ichikawa;Mako Kamiya;Mako Kamiya;Toru Komatsu

  • Real-time measurements of protein dynamics using fluorescence activation-coupled protein labeling method.

    Toru Komatsu;Kai Johnsson;Hiroyuki Okuno;Haruhiko Bito

  • Design strategy for a near-infrared fluorescence probe for matrix metalloproteinase utilizing highly cell permeable boron dipyrromethene

    Takuya Myochin;Kenjiro Hanaoka;Toru Komatsu;Takuya Terai

  • Development of a Series of Practical Fluorescent Chemical Tools To Measure pH Values in Living Samples

    Shodai Takahashi;Yu Kagami;Kenjiro Hanaoka;Takuya Terai

  • Highly activatable and environment-insensitive optical highlighters for selective spatiotemporal imaging of target proteins

    Tomonori Kobayashi;Toru Komatsu;Mako Kamiya;Cláudia Campos;Cláudia Campos

  • Development of a series of near-infrared dark quenchers based on Si-rhodamines and their application to fluorescent probes.

    Takuya Myochin;Kenjiro Hanaoka;Shimpei Iwaki;Tasuku Ueno

  • Reversible Off–On Fluorescence Probe for Hypoxia and Imaging of Hypoxia–Normoxia Cycles in Live Cells

    Shodai Takahashi;Wen Piao;Yuriko Matsumura;Toru Komatsu

  • Design and Synthesis of an Enzyme Activity-Based Labeling Molecule with Fluorescence Spectral Change

    Toru Komatsu;Kazuya Kikuchi;Hideo Takakusa;Kenjiro Hanaoka

  • Boron dipyrromethene as a fluorescent caging group for single-photon uncaging with long-wavelength visible light.

    Nobuhiro Umeda;Hironori Takahashi;Mako Kamiya;Tasuku Ueno

  • Selective Ablation of β‐Galactosidase‐Expressing Cells with a Rationally Designed Activatable Photosensitizer

    Yuki Ichikawa;Mako Kamiya;Fumiaki Obata;Masayuki Miura

  • Discovery and Mechanistic Characterization of Selective Inhibitors of H 2 S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide.

    Kenjiro Hanaoka;Kiyoshi Sasakura;Yusuke Suwanai;Sachiko Toma-Fukai

  • Development of 2,6-carboxy-substituted boron dipyrromethene (BODIPY) as a novel scaffold of ratiometric fluorescent probes for live cell imaging

    Toru Komatsu;Yasuteru Urano;Yuuta Fujikawa;Tomonori Kobayashi

Frequent Co-Authors

Yasuteru Urano
Yasuteru Urano University of Tokyo
Kenjiro Hanaoka
Kenjiro Hanaoka Keio University
Tetsuo Nagano
Tetsuo Nagano University of Tokyo
Takuya Terai
Takuya Terai University of Tokyo
Hirotatsu Kojima
Hirotatsu Kojima University of Tokyo
Yuji Ikegaya
Yuji Ikegaya University of Tokyo
Masanobu Uchiyama
Masanobu Uchiyama University of Tokyo
Wolf B. Frommer
Wolf B. Frommer Heinrich Heine University Düsseldorf
Hideo Kimura
Hideo Kimura University of Tokyo
Norio Matsuki
Norio Matsuki Tokyo University of Science

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