Toshihiro Nukiwa

Overview

Best Publications

• Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR

  Makoto Maemondo;Akira Inoue;Kunihiko Kobayashi;Shunichi Sugawara

  7431
  Citations

• Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

  Yoichiro Mitsuishi;Keiko Taguchi;Yukie Kawatani;Tatsuhiro Shibata

  1386
  Citations

• Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis

  Arata Azuma;Toshihiro Nukiwa;Eiyasu Tsuboi;Moritaka Suga

  1265
  Citations

• Pirfenidone in idiopathic pulmonary fibrosis

  H Taniguchi;M Ebina;Y Kondoh;T Ogura

  1170
  Citations

• Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations.

  Akira Inoue;Takuji Suzuki;Tatsuro Fukuhara;Makoto Maemondo

  732
  Citations

• Molecular basis of alpha-1-antitrypsin deficiency

  Mark Brantly;Toshihiro Nukiwa;Ronald G. Crystal

  679
  Citations

• First-Line Gefitinib for Patients With Advanced Non–Small-Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Mutations Without Indication for Chemotherapy

  Akira Inoue;Kunihiko Kobayashi;Kazuhiro Usui;Makoto Maemondo

  661
  Citations

• Updated overall survival results from a randomized phase III trial comparing gefitinib with carboplatin–paclitaxel for chemo-naïve non-small cell lung cancer with sensitive EGFR gene mutations (NEJ002)

  A. Inoue;K. Kobayashi;M. Maemondo;S. Sugawara

  653
  Citations

• Severe acute interstitial pneumonia and gefitinib.

  Akira Inoue;Yasuo Saijo;Makoto Maemondo;Kazunori Gomi

  632
  Citations

• Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-squamous non-small-cell lung cancer (NEJ026): interim analysis of an open-label, randomised, multicentre, phase 3 trial

  Haruhiro Saito;Tatsuro Fukuhara;Naoki Furuya;Kana Watanabe

  603
  Citations

• Characteristics of a Large Cohort of Patients with Autoimmune Pulmonary Alveolar Proteinosis in Japan

  Yoshikazu Inoue;Bruce C. Trapnell;Ryushi Tazawa;Toru Arai

  589
  Citations

• A Japanese Lung Cancer Registry Study: Prognosis of 13,010 Resected Lung Cancers

  Hisao Asamura;Tomoyuki Goya;Yoshihiko Koshiishi;Yasunori Sohara

  478
  Citations

• Gefitinib Alone Versus Gefitinib Plus Chemotherapy for Non-Small-Cell Lung Cancer With Mutated Epidermal Growth Factor Receptor: NEJ009 Study.

  Yukio Hosomi;Satoshi Morita;Shunichi Sugawara;Terufumi Kato

  419
  Citations

• Epidemiology of sarcoidosis in Japan

  T Morimoto;A Azuma;S Abe;J Usuki

  409
  Citations

• Fcgamma receptor IIB-deficient mice develop Goodpasture's syndrome upon immunization with type IV collagen: a novel murine model for autoimmune glomerular basement membrane disease.

  Akira Nakamura;Takae Yuasa;Azusa Ujike;Masao Ono

  360
  Citations

• Proinflammatory Cytokine IL-1β Promotes Tumor Growth of Lewis Lung Carcinoma by Induction of Angiogenic Factors: In Vivo Analysis of Tumor-Stromal Interaction

  Yasuo Saijo;Masashi Tanaka;Makoto Miki;Kazuhiro Usui

  342
  Citations

• Heterogeneous increase in CD34-positive alveolar capillaries in idiopathic pulmonary fibrosis.

  Masahito Ebina;Minoru Shimizukawa;Naoko Shibata;Yuichiro Kimura

  340
  Citations

• Infiltration of COX-2–expressing macrophages is a prerequisite for IL-1β–induced neovascularization and tumor growth

  Shintaro Nakao;Takashi Kuwano;Chikako Tsutsumi-Miyahara;Shu Ichi Ueda

  329
  Citations

• Alveolar macrophages release an insulin-like growth factor I-type molecule.

  W N Rom;P Basset;G A Fells;T Nukiwa

  316
  Citations

• A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis.

  T Mushiroda;S Wattanapokayakit;A Takahashi;T Nukiwa

  308
  Citations