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Chemistry

D-Index
80
Citations
29339
World Ranking
3364
National Ranking
1108

Overview

Lee Josephson is affiliated with Harvard University in the United States. Their research spans numerous fields, predominantly within Medicine and Biochemistry, Genetics and Molecular Biology. Subfields in which they have published include Molecular Biology, Physiology, Neurology, Pharmacology, and Radiology, Nuclear Medicine and Imaging.

Their research topics cover a range of areas with notable focus on:

  • Alzheimer's disease research and treatments
  • Neuroscience and Neuropharmacology Research
  • Radiopharmaceutical Chemistry and Applications
  • Chemical Synthesis and Analysis
  • Cannabis and Cannabinoid Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Adenosine and Purinergic Signaling

Recent papers authored or coauthored by Lee Josephson include:

  • Radiochemistry for positron emission tomography, 2023, Nature Communications
  • Recent developments on PET radiotracers for TSPO and their applications in neuroimaging, 2020, Acta Pharmaceutica Sinica B
  • The Repertoire of Small-Molecule PET Probes for Neuroinflammation Imaging: Challenges and Opportunities beyond TSPO, 2021, Journal of Medicinal Chemistry
  • [18F]-Alfatide PET imaging of integrin αvβ3 for the non-invasive quantification of liver fibrosis, 2020, Journal of Hepatology
  • In Vitro Evaluation of [3H]CPPC as a Tool Radioligand for CSF-1R, 2021, ACS Chemical Neuroscience

Lee Josephson frequently collaborates with other researchers. Their most consistent coauthors include Steven H. Liang, Jian Rong, Tuo Shao, Zhen Chen, and Ming-Rong Zhang.

Their publications appear regularly in established venues, including:

  • Journal of Medicinal Chemistry
  • Acta Pharmaceutica Sinica B
  • International Journal of Nanomedicine
  • Acta Pharmacologica Sinica
  • Bioorganic & Medicinal Chemistry Letters

Best Publications

  • Ultrasmall superparamagnetic iron oxide: characterization of a new class of contrast agents for MR imaging.

    R Weissleder;G Elizondo;J Wittenberg;C A Rabito

  • High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates.

    Lee Josephson;Ching-Hsuan Tung;and Anna Moore;Ralph Weissleder

  • Cell-specific targeting of nanoparticles by multivalent attachment of small molecules.

    Ralph Weissleder;Kimberly Kelly;Eric Yi Sun;Timur Shtatland

  • Vanadate is a potent (Na,K)-ATPase inhibitor found in ATP derived from muscle.

    L C Cantley;L Josephson;R Warner;M Yanagisawa

  • Magnetic relaxation switches capable of sensing molecular interactions

    J. Manuel Perez;Lee Josephson;Terrence O'Loughlin;Dagmar Högemann

  • Magnetic particles for use in separations

    Mark Steven Chagnon;Ernest Victor Groman;Lee Josephson;Roy Arthur Whitehead

  • A Multimodal Nanoparticle for Preoperative Magnetic Resonance Imaging and Intraoperative Optical Brain Tumor Delineation

    Moritz F. Kircher;Umar Mahmood;Raymond S. King;Ralph Weissleder

  • Viral-Induced Self-Assembly of Magnetic Nanoparticles Allows the Detection of Viral Particles in Biological Media

    J Manuel Perez;F Joseph Simeone;Yoshinaga Saeki;Lee Josephson

  • A characterization of vanadate interactions with the (Na,K)-ATPase. Mechanistic and regulatory implications.

    L C Cantley;L G Cantley;L Josephson

  • Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging.

    R Weissleder;G Elizondo;J Wittenberg;A S Lee

  • Detection of Vascular Adhesion Molecule-1 Expression Using a Novel Multimodal Nanoparticle

    Kimberly A. Kelly;Jennifer R. Allport;Andrew Tsourkas;Vivek R. Shinde-Patil

  • Magnetic Nanosensors for the Detection of Oligonucleotide Sequences.

    Lee Josephson;J. Manuel Perez;Ralph Weissleder

  • Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes.

    Lee Josephson;Moritz F Kircher;Umar Mahmood;Yi Tang

  • Multivalent effects of RGD peptides obtained by nanoparticle display.

    Xavier Montet;Martin Funovics;Karin Montet-Abou;Ralph Weissleder

  • In Vivo High Resolution Three-Dimensional Imaging of Antigen-Specific Cytotoxic T-Lymphocyte Trafficking to Tumors

    Moritz F. Kircher;Jennifer R. Allport;Edward E. Graves;Victoria Love

  • Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V–Cy5.5 conjugate

    Vasilis Ntziachristos;Eyk A. Schellenberger;Jorge Ripoll;Doreen Yessayan

  • Differential conjugation of tat peptide to superparamagnetic nanoparticles and its effect on cellular uptake

    Ming Zhao;Moritz F Kircher;Lee Josephson;Ralph Weissleder

  • DNA-Based Magnetic Nanoparticle Assembly Acts as a Magnetic Relaxation Nanoswitch Allowing Screening of DNA-Cleaving Agents

    J. Manuel Perez;Terence O'loughin;F. Joseph Simeone;Ralph Weissleder

  • Magnetic Nanoparticle Sensors

    Isaac Koh;Lee Josephson

  • Tat peptide directs enhanced clearance and hepatic permeability of magnetic nanoparticles.

    Patrick Wunderbaldinger;Lee Josephson;Ralph Weissleder

  • Isolation of a potent (Na -K) stimulated ATPase inhibitor from striated muscle

    Lee Josephson;Lewis C. Cantley

  • Use of Magnetic Nanoparticles as Nanosensors to Probe for Molecular Interactions

    J. Manuel Perez;Lee Josephson;Ralph Weissleder

  • Nanoparticle imaging of integrins on tumor cells.

    Xavier Montet;Karin Montet-Abou;Fred Reynolds;Ralph Weissleder

  • A Characterization of Vanadate Interactions with the (Na,K)-ATPase

    Lewis C. Cantley;Lloyd G. Cantley;Lee Josephson

Frequent Co-Authors

Ralph Weissleder
Ralph Weissleder Harvard University
Alexei A. Bogdanov
Alexei A. Bogdanov University of Massachusetts Chan Medical School
Georges El Fakhri
Georges El Fakhri Harvard University
Lewis C. Cantley
Lewis C. Cantley Harvard University
Matthias Nahrendorf
Matthias Nahrendorf Harvard University
Vasilis Ntziachristos
Vasilis Ntziachristos Technical University of Munich
Anthony Rosenzweig
Anthony Rosenzweig Harvard University
Elena Aikawa
Elena Aikawa Brigham and Women's Hospital
Ronglih Liao
Ronglih Liao Stanford University
Ching-Hsuan Tung
Ching-Hsuan Tung Cornell University

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