What is he best known for?
The fields of study he is best known for:
- Gene
- Amino acid
- Biochemistry
Stephen J. Tucker mainly investigates Potassium channel, Biochemistry, Biophysics, Protein subunit and Kir6.2.
Sulfonylurea receptor is the focus of his Potassium channel research.
Stephen J. Tucker is studying Adenosine triphosphate, which is a component of Biochemistry.
Stephen J. Tucker is interested in Gating, which is a branch of Biophysics.
His studies examine the connections between Protein subunit and genetics, as well as such issues in Inward-rectifier potassium ion channel, with regards to KCNJ10 and ROMK.
His Kir6.2 research is multidisciplinary, incorporating elements of Photoaffinity labeling, ATP synthase alpha/beta subunits, Intracellular and Gi alpha subunit.
His most cited work include:
- Truncation of Kir6.2 produces ATP-sensitive K + channels in the absence of the sulphonylurea receptor (693 citations)
- PIP2 and PIP as Determinants for ATP Inhibition of KATP Channels (467 citations)
- The essential role of the Walker A motifs of SUR1 in K‐ATP channel activation by Mg‐ADP and diazoxide (317 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Biophysics, Potassium channel, Gating, Ion channel and Biochemistry.
In his research on the topic of Biophysics, Molecular biology is strongly related with Xenopus.
Stephen J. Tucker has researched Potassium channel in several fields, including Genetics, Intracellular, Cell biology and Protein subunit.
Stephen J. Tucker has included themes like Helix bundle, Voltage-gated ion channel, Intracellular pH, Stereochemistry and KcsA potassium channel in his Gating study.
His Ion channel study combines topics in areas such as Chemical physics, Membrane, Lipid bilayer and Nanotechnology.
His Sulfonylurea receptor research includes elements of Diazoxide and ATP-sensitive potassium channel.
He most often published in these fields:
- Biophysics (47.28%)
- Potassium channel (46.20%)
- Gating (34.24%)
What were the highlights of his more recent work (between 2017-2021)?
- Ion channel (26.63%)
- Biophysics (47.28%)
- Chemical physics (8.70%)
In recent papers he was focusing on the following fields of study:
Stephen J. Tucker spends much of his time researching Ion channel, Biophysics, Chemical physics, Gating and Nanopore.
His work carried out in the field of Ion channel brings together such families of science as Missense mutation, Nanoscopic scale, Xenopus and Permeation.
He studies Biophysics, focusing on Potassium channel in particular.
His Potassium channel research incorporates elements of Genetics, Aura, Mutation, KCNJ5 Gene and Mutant.
The study incorporates disciplines such as Wetting, Dewetting and Radius in addition to Chemical physics.
His Gating research is multidisciplinary, incorporating perspectives in Membrane, Depolarization and Intracellular.
Between 2017 and 2021, his most popular works were:
- Rare NaV1.7 variants associated with painful diabetic peripheral neuropathy. (66 citations)
- A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels. (40 citations)
- CHAP: A Versatile Tool for the Structural and Functional Annotation of Ion Channel Pores (37 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Amino acid
- Ion channel
His main research concerns Ion channel, Biophysics, Chemical physics, Biological membrane and Nanopore.
The various areas that Stephen J. Tucker examines in his Ion channel study include Flumazenil, De wetting, Ion flow and Nanotechnology.
When carried out as part of a general Biophysics research project, his work on Membrane potential and Potassium channel is frequently linked to work in Vestibule and Vascular smooth muscle, therefore connecting diverse disciplines of study.
His Chemical physics study combines topics from a wide range of disciplines, such as Nanoscopic scale and Lipid bilayer.
His biological study spans a wide range of topics, including CALHM1, Bilayer and Connexin, Innexin, Pannexin.
He combines subjects such as Wetting, Dewetting, Steric effects, Radius and Permeation with his study of Nanopore.
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