World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
12097
World Ranking
13806
National Ranking
1082

Overview

Stephen J. Tucker is affiliated with the University of Oxford in the United Kingdom and specializes in research within the broad field of Biochemistry, Genetics and Molecular Biology. Their work primarily concentrates on Molecular Biology, with additional focus areas including Biomedical Engineering, Cellular and Molecular Neuroscience, Cardiology and Cardiovascular Medicine, and Atomic and Molecular Physics, and Optics.

The scientist's research topics encompass several domains, notably Ion channel regulation and function, Nanopore and Nanochannel Transport Studies, and Cardiac electrophysiology and arrhythmias. Other areas of study include Spectroscopy and Quantum Chemical Studies, Lipid Membrane Structure and Behavior, Microfluidic and Capillary Electrophoresis Applications, as well as Nicotinic Acetylcholine Receptors Study.

Stephen J. Tucker has published extensively, with frequent contributions to venues such as bioRxiv (Cold Spring Harbor Laboratory), Biophysical Journal, Nature Structural & Molecular Biology, ACS Nano, and The Journal of General Physiology. Their recent notable papers include:

  • A lower X-gate in TASK channels traps inhibitors within the vestibule, 2020, Nature
  • Structure and assembly of calcium homeostasis modulator proteins, 2020, Nature Structural & Molecular Biology
  • Structure and assembly of calcium homeostasis modulator proteins., 2020, PubMed
  • Induced Polarization in Molecular Dynamics Simulations of the 5-HT 3 Receptor Channel, 2020, Journal of the American Chemical Society
  • Electric Field Induced Wetting of a Hydrophobic Gate in a Model Nanopore Based on the 5-HT 3 Receptor Channel, 2020, ACS Nano

Collaboration is a significant aspect of the scientist's output, with frequent coauthors including Mark S.P. Sansom, Shanlin Rao, Peter Proks, Karin E. J. Rödström, and Marcus Schewe.

Best Publications

  • Truncation of Kir6.2 produces ATP-sensitive K + channels in the absence of the sulphonylurea receptor

    Stephen J. Tucker;Fiona M. Gribble;Chao Zhao;Stefan Trapp

  • The essential role of the Walker A motifs of SUR1 in K‐ATP channel activation by Mg‐ADP and diazoxide

    Fiona M. Gribble;Stephen J. Tucker;Frances M. Ashcroft

  • Tissue specificity of sulfonylureas: studies on cloned cardiac and beta-cell K(ATP) channels.

    F M Gribble;S J Tucker;S Seino;F M Ashcroft

  • PIP2 and PIP as Determinants for ATP Inhibition of KATP Channels

    Thomas Baukrowitz;Uwe Schulte;Dominik Oliver;Stefan Herlitze

  • A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura.

    Ronald G Lafrenière;M Zameel Cader;M Zameel Cader;Jean-François Poulin;Isabelle Andres-Enguix

  • K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac

    Yin Yao Dong;Ashley C. W. Pike;Alexandra Mackenzie;Alexandra Mackenzie;Conor McClenaghan

  • A Novel Method for Measurement of Submembrane ATP Concentration

    Fiona M. Gribble;Gildas Loussouarn;Stephen J. Tucker;Chao Zhao

  • Molecular determinants of KATP channel inhibition by ATP.

    Stephen J. Tucker;Fiona M. Gribble;Peter Proks;Stefan Trapp

  • Hydrophobic gating in ion channels.

    Prafulla Aryal;Mark S.P. Sansom;Stephen J. Tucker

  • The pore structure and gating mechanism of K2P channels: K2P channel gating

    Paula L Piechotta;Markus Rapedius;Phillip J Stansfeld;Murali K Bollepalli

  • Subunit positional effects revealed by novel heteromeric inwardly rectifying K+ channels.

    Mauro Pessia;Stephen J. Tucker;Kevin Lee;Chris T. Bond

  • A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K+ Channels

    Marcus Schewe;Ehsan Nematian-Ardestani;Han Sun;Han Sun;Marianne Musinszki

  • MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit.

    Fiona M. Gribble;Stephen J. Tucker;Trude Haug;Frances M. Ashcroft

  • The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation.

    Fiona M. Gribble;Stephen J. Tucker;Frances M. Ashcroft

  • Molecular Analysis of ATP-sensitive K Channel Gating and Implications for Channel Inhibition by ATP

    Stefan Trapp;Peter Proks;Stephen J. Tucker;Frances M. Ashcroft

  • The pore structure and gating mechanism of K2P channels

    Paula L Piechotta;Markus Rapedius;Phillip J Stansfeld;Murali K Bollepalli

  • A divergent CFTR homologue: highly regulated salt transport in the euryhaline teleost F. heteroclitus

    Thomas D. Singer;Stephen J. Tucker;William S. Marshall;Christopher F. Higgins

  • Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1.

    Mauro Pessia;Paola Imbrici;Maria Cristina D'Adamo;Lorena Salvatore

  • De novo point mutations in patients diagnosed with ataxic cerebral palsy

    Ricardo Parolin Schnekenberg;Ricardo Parolin Schnekenberg;Emma M. Perkins;Jack W. Miller;Wayne L. Davies;Wayne L. Davies;Wayne L. Davies

  • pH dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia.

    Stephen J. Tucker;Paola Imbrici;Lorena Salvatore;Maria Cristina D'Adamo

Frequent Co-Authors

Mark S.P. Sansom
Mark S.P. Sansom University of Oxford
Frances M. Ashcroft
Frances M. Ashcroft University of Oxford
Phillip J. Stansfeld
Phillip J. Stansfeld University of Warwick
Fiona M. Gribble
Fiona M. Gribble University of Cambridge
Nikolaus Grigorieff
Nikolaus Grigorieff Howard Hughes Medical Institute
George C. Ebers
George C. Ebers University of Oxford
Colin G. Nichols
Colin G. Nichols Washington University in St. Louis
Guy A. Rouleau
Guy A. Rouleau Montreal Neurological Institute and Hospital
Frank Reimann
Frank Reimann University of Cambridge
Lyn R. Griffiths
Lyn R. Griffiths Queensland University of Technology

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Stephen J. Tucker

Trending Scientists