Michael H. Ossipov

Overview

Best Publications

• Central modulation of pain

  Michael H. Ossipov;Gregory O. Dussor;Frank Porreca

  1416
  Citations

• Chronic pain and medullary descending facilitation

  Frank Porreca;Michael H Ossipov;G.F Gebhart

  1145
  Citations

• Potent and nontoxic antisense oligonucleotides containing locked nucleic acids

  Claes R Wahlestedt;Peter Salmi;Liam Good;Johanna Kela

  894
  Citations

• Descending pain modulation and chronification of pain.

  Michael H. Ossipov;Kozo Morimura;Frank Porreca

  747
  Citations

• The role of calcitonin gene-related peptide in peripheral and central pain mechanisms including migraine.

  Smriti Iyengar;Michael H. Ossipov;Kirk W. Johnson

  627
  Citations

• Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8.

  Josephine Lai;Michael S Gold;Chang Sook Kim;Di Bian

  589
  Citations

• Efficacy and safety of galcanezumab for the prevention of episodic migraine: Results of the EVOLVE-2 Phase 3 randomized controlled clinical trial:

  Vladimir Skljarevski;Manjit Matharu;Brian A Millen;Michael H Ossipov

  506
  Citations

• A Comparison of the Potential Role of the Tetrodotoxin-Insensitive Sodium Channels, PN3/SNS and NaN/SNS2, in Rat Models of Chronic Pain

  Frank Porreca;Josephine Lai;D. I. Bian;Sandra Wegert

  490
  Citations

• CGRP and the Trigeminal System in Migraine.

  Smriti Iyengar;Kirk W. Johnson;Michael H. Ossipov;Sheena K. Aurora

  479
  Citations

• Dynorphin Promotes Abnormal Pain and Spinal Opioid Antinociceptive Tolerance

  Todd W. Vanderah;Luis R. Gardell;Shannon E. Burgess;Mohab Ibrahim

  411
  Citations

• Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain.

  Shannon E. Burgess;Luis R. Gardell;Michael H. Ossipov;T. Philip Malan

  403
  Citations

• Tonic Descending Facilitation from the Rostral Ventromedial Medulla Mediates Opioid-Induced Abnormal Pain and Antinociceptive Tolerance

  Todd W. Vanderah;Nova M. H. Suenaga;Michael H. Ossipov;T. Philip Malan

  390
  Citations

• Spinal and Supraspinal Mechanisms of Neuropathic Pain

  Michael H. Ossipov;Josephine Lai;T. Philip Malan;Frank Porreca

  371
  Citations

• Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin.

  Todd W. Vanderah;Michael H. Ossipov;Josephine Lai;T.Philip Malan

  369
  Citations

• Pronociceptive actions of dynorphin maintain chronic neuropathic pain.

  Zaijie Wang;Luis R. Gardell;Michael H. Ossipov;Todd W. Vanderah

  361
  Citations

• Pain relief produces negative reinforcement through activation of mesolimbic reward–valuation circuitry

  Edita Navratilova;Jennifer Y. Xie;Alec Okun;Chaoling Qu

  346
  Citations

• Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats.

  Michael H. Ossipov;Di Bian;T.Philip Malan;Josephine Lai

  319
  Citations

• Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: blockade by MK-801 but not naloxone

  Todd W Vandera;Tinna Laughlin;Jason M. Lashbrook;Michael L. Nichols

  317
  Citations

• Sustained morphine exposure induces a spinal dynorphin-dependent enhancement of excitatory transmitter release from primary afferent fibers.

  Luis R. Gardell;Ruizhong Wang;Shannon E. Burgess;Michael H. Ossipov

  316
  Citations

• Underlying mechanisms of pronociceptive consequences of prolonged morphine exposure.

  Michael H. Ossipov;Josephine Lai;Tamara King;Todd W. Vanderah

  311
  Citations