Michael H. Ossipov mainly focuses on Neuroscience, Neuropathic pain, Hyperalgesia, Anesthesia and Nociception. His Neuropathic pain research is multidisciplinary, incorporating elements of Nerve impulse, Nerve injury, Sensory system, Dorsal root ganglion and Dynorphin. His research integrates issues of Endocrinology and Dynorphin A in his study of Dynorphin.
His Hyperalgesia research incorporates themes from Cholecystokinin and Spinal cord. His study in Nociception is interdisciplinary in nature, drawing from both Morphine, Central nervous system, Analgesic and Opioid. His Opioid research is multidisciplinary, incorporating perspectives in Noxious stimulus, Pharmacology and Rostral ventromedial medulla.
Michael H. Ossipov mainly investigates Anesthesia, Pharmacology, Neuropathic pain, Nociception and Neuroscience. His Anesthesia research incorporates elements of Sumatriptan, Rostral ventromedial medulla and Allodynia. In Pharmacology, Michael H. Ossipov works on issues like Clonidine, which are connected to Alpha-2 adrenergic receptor.
His work in Neuropathic pain addresses issues such as Nerve injury, which are connected to fields such as Spinal nerve and Sciatic nerve. His studies in Nociception integrate themes in fields like Dynorphin, Endocrinology and Opioid. His work carried out in the field of Neuroscience brings together such families of science as Glial cell line-derived neurotrophic factor and Nociceptor.
The scientist’s investigation covers issues in Neuropathic pain, Anesthesia, Migraine, Pharmacology and Neuroscience. His studies deal with areas such as Morphine, Nociception, Endogenous opioid, Opioid and Spinal cord as well as Neuropathic pain. His Endogenous opioid research focuses on Dynorphin and how it connects with Endocrinology and Lumbar Spinal Cord.
Michael H. Ossipov has included themes like Opioid analgesics, Dopaminergic and Nucleus accumbens in his Anesthesia study. His Pharmacology study combines topics from a wide range of disciplines, such as Chronic pain, κ-opioid receptor and Allodynia. In his study, Periaqueductal gray is strongly linked to Serotonergic, which falls under the umbrella field of Neuroscience.
His primary areas of investigation include Migraine, Calcitonin gene-related peptide, Anesthesia, Conditioned place preference and Neuropathic pain. Michael H. Ossipov interconnects Clinical endpoint, Quality of life, Pharmacology and Allodynia in the investigation of issues within Calcitonin gene-related peptide. His Conditioned place preference study combines topics in areas such as Dopaminergic, Nucleus accumbens and Rostral ventromedial medulla.
His Rostral ventromedial medulla study combines topics from a wide range of disciplines, such as Lidocaine, Nerve injury, Lesion and Spinal cord. His Neuropathic pain research is included under the broader classification of Neuroscience. His research integrates issues of Morphine, Hyperalgesia and Opioid in his study of Dopamine.
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Central modulation of pain
Michael H. Ossipov;Gregory O. Dussor;Frank Porreca.
Journal of Clinical Investigation (2010)
Chronic pain and medullary descending facilitation
Frank Porreca;Michael H Ossipov;G.F Gebhart.
Trends in Neurosciences (2002)
Potent and nontoxic antisense oligonucleotides containing locked nucleic acids
Claes R Wahlestedt;Peter Salmi;Liam Good;Johanna Kela.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Descending pain modulation and chronification of pain.
Michael H. Ossipov;Kozo Morimura;Frank Porreca.
Current Opinion in Supportive and Palliative Care (2014)
Dynorphin Promotes Abnormal Pain and Spinal Opioid Antinociceptive Tolerance
Todd W. Vanderah;Luis R. Gardell;Shannon E. Burgess;Mohab Ibrahim.
The Journal of Neuroscience (2000)
A Comparison of the Potential Role of the Tetrodotoxin-Insensitive Sodium Channels, PN3/SNS and NaN/SNS2, in Rat Models of Chronic Pain
Frank Porreca;Josephine Lai;D. I. Bian;Sandra Wegert.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain.
Shannon E. Burgess;Luis R. Gardell;Michael H. Ossipov;T. Philip Malan.
The Journal of Neuroscience (2002)
Tonic Descending Facilitation from the Rostral Ventromedial Medulla Mediates Opioid-Induced Abnormal Pain and Antinociceptive Tolerance
Todd W. Vanderah;Nova M. H. Suenaga;Michael H. Ossipov;T. Philip Malan.
The Journal of Neuroscience (2001)
Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin.
Todd W. Vanderah;Michael H. Ossipov;Josephine Lai;T.Philip Malan.
Pain (2001)
Spinal and Supraspinal Mechanisms of Neuropathic Pain
Michael H. Ossipov;Josephine Lai;T. Philip Malan;Frank Porreca.
Annals of the New York Academy of Sciences (2006)
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