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Genetics

D-Index
66
Citations
17093
World Ranking
2606
National Ranking
90

Overview

Richard A. Sturm is affiliated with the University of Queensland in Australia. Their academic work spans multiple fields related to medicine and molecular biology, with a focus on oncology, cell biology, dermatology, and epidemiology.

The research primarily addresses several key topics, including:

  • Cutaneous Melanoma Detection and Management
  • Melanin and Skin Pigmentation
  • Melanoma and MAPK Pathways
  • Cancer Genomics and Diagnostics
  • Skin Protection and Aging
  • Sirtuins and Resveratrol in Medicine
  • Autophagy in Disease and Therapy

Their frequent co-authors include:

  • H. Peter Soyer (22 co-publications)
  • Mitchell Stark (16 co-publications)
  • Darren J. Smit (10 co-publications)
  • Kasturee Jagirdar (9 co-publications)
  • Aideen McInerney-Leo (9 co-publications)

Richard A. Sturm has published extensively in various scientific venues, with the most frequent publication outlets being:

  • British Journal of Dermatology (5 papers)
  • Journal of Investigative Dermatology (5 papers)
  • Journal of the European Academy of Dermatology and Venereology (3 papers)
  • Pigment Cell & Melanoma Research (2 papers)
  • Journal of Medical Genetics (2 papers)

Recent publications include:

  • The Eumelanin Human Skin Colour Scale: a proof-of-concept study (2022, British Journal of Dermatology)
  • The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics (2021, Journal of Clinical Investigation)
  • Germline and somatic albinism variants in amelanotic/hypomelanotic melanoma: Increased carriage of TYR and OCA2 variants (2020, PLoS ONE)
  • Genome-Scale DNA Methylation Analysis Identifies Repeat Element Alterations that Modulate the Genomic Stability of Melanocytic Nevi (2021, Journal of Investigative Dermatology)
  • On Naevi and Melanomas: Two Sides of the Same Coin? (2021, Frontiers in Medicine)

The research output reflects engagement with molecular mechanisms underlying melanoma and skin pigmentation, as well as genomic and epigenomic studies aimed at understanding melanoma progression and diagnostics.

Overall, the work of Richard A. Sturm integrates interdisciplinary approaches combining dermatology, molecular biology, and oncology. The focus on melanoma detection, the molecular basis of pigmentation, and cancer genomics illustrates a complex research portfolio dedicated to advancing knowledge in these intersecting areas of health science.

Best Publications

  • The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products

    W Herr;R A Sturm;R G Clerc;L M Corcoran

  • The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

    R A Sturm;G Das;W Herr

  • Melanocortin-1 Receptor Polymorphisms and Risk of Melanoma: Is the Association Explained Solely by Pigmentation Phenotype?

    James S. Palmer;James S. Palmer;David L. Duffy;Neil F. Box;Joanne F. Aitken

  • Human pigmentation genes: identification, structure and consequences of polymorphic variation

    Richard A Sturm;Rohan D Teasdale;Neil F Box

  • Molecular genetics of human pigmentation diversity

    Richard A. Sturm

  • A Single SNP in an Evolutionary Conserved Region within Intron 86 of the HERC2 Gene Determines Human Blue-Brown Eye Color

    Richard A. Sturm;David L. Duffy;Zhen Zhen Zhao;Fabio P.N. Leite

  • Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European

    Inigo Olalde;Morten Erik Allentoft;Federico Sanchez-Quinto;Gabriel Santpere

  • Characterization of Melanocyte Stimulating Hormone Receptor Variant Alleles in Twins with Red Hair

    Neil F. Box;Jason R. Wyeth;Louise E. O'Gorman;Nicholas G. Martin

  • MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations

    Neil F. Box;David L. Duffy;Wei Chen;Mitchell Stark

  • The POU domain is a bipartite DNA-binding structure

    Richard A. Sturm;Winship Herr

  • Interactive effects of MC1R and OCA2 on melanoma risk phenotypes

    David L. Duffy;Neil F. Box;Wei Chen;James S. Palmer

  • A three-single-nucleotide polymorphism haplotype in intron 1 of OCA2 explains most human eye-color variation

    David L. Duffy;Grant W. Montgomery;Wei Chen;Zhen Zhen Zhao

  • Skin colour and skin cancer - MC1R, the genetic link.

    Sturm Ra

  • Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma.

    David L. Duffy;Zhen Z. Zhao;Richard A. Sturm;Richard A. Sturm;Nicholas K. Hayward

  • A 100-kD HeLa cell octamer binding protein (OBP100) interacts differently with two separate octamer-related sequences within the SV40 enhancer.

    R Sturm;T Baumruker;B R Franza;W Herr

  • Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia- Associated Transcription Factor-Negative Melanoma Cells

    Jane Goodall;Suzanne Carreira;Laurence Denat;Dominique Kobi

  • HUMAN PIGMENTATION GENETICS : THE DIFFERENCE IS ONLY SKIN DEEP

    Richard A. Sturm;Neil F. Box;Michele Ramsay

  • Mutation in and lack of expression of tyrosinase-related protein-1 (TRP-1) in melanocytes from an individual with brown oculocutaneous albinism: a new subtype of albinism classified as "OCA3".

    R. E. Boissy;H. Q. Zhao;W. S. Oetting;L. M. Austin

  • Genetics of human iris colour and patterns

    Richard A. Sturm;Mats Larsson;Mats Larsson

  • Eye colour: portals into pigmentation genes and ancestry.

    Richard A. Sturm;Tony N. Frudakis

Frequent Co-Authors

David L. Duffy
David L. Duffy QIMR Berghofer Medical Research Institute
H. Peter Soyer
H. Peter Soyer University of Queensland
Peter G. Parsons
Peter G. Parsons QIMR Berghofer Medical Research Institute
Nicholas G. Martin
Nicholas G. Martin QIMR Berghofer Medical Research Institute
Grant W. Montgomery
Grant W. Montgomery University of Queensland
Nicholas K. Hayward
Nicholas K. Hayward QIMR Berghofer Medical Research Institute
Adèle C. Green
Adèle C. Green QIMR Berghofer Medical Research Institute
Brian Gabrielli
Brian Gabrielli University of Queensland
Meenhard Herlyn
Meenhard Herlyn The Wistar Institute
Anjali K. Henders
Anjali K. Henders University of Queensland

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