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Genetics

D-Index
108
Citations
39811
World Ranking
566
National Ranking
23

Overview

Manfred Kayser is affiliated with Erasmus University Rotterdam in the Netherlands, focusing on areas within biochemistry, genetics, and molecular biology. Their research spans a range of subjects primarily centered on molecular biology, genetics, cell biology, dermatology, and archeology.

The scientist's work has a strong emphasis on forensic and genetic research, epigenetics and DNA methylation, and molecular biology techniques and applications. Additional topics of interest include genetic associations and epidemiology, melanin and skin pigmentation, skin protection and aging, as well as forensic anthropology and bioarchaeology studies.

Manfred Kayser has contributed to numerous publications in several key scientific venues. Frequent publication venues include Forensic Science International Genetics, bioRxiv (Cold Spring Harbor Laboratory), Aging, Nature Communications, and Clinical Epigenetics.

Several notable recent papers demonstrate the range and focus of their research:

  • "GenNet framework: interpretable deep learning for predicting phenotypes from genetic data," 2021, Communications Biology
  • "Development of the VISAGE enhanced tool and statistical models for epigenetic age estimation in blood, buccal cells and bones," 2021, Aging
  • "Recent advances in Forensic DNA Phenotyping of appearance, ancestry and age," 2023, Forensic Science International Genetics
  • "Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color," 2021, Science Advances
  • "Development and validation of the VISAGE AmpliSeq basic tool to predict appearance and ancestry from DNA," 2020, Forensic Science International Genetics

The scientist has collaborated frequently with several coauthors, including Athina Vidaki, Arwin Ralf, Walther Parson, Fan Liu, and M. Arfan Ikram.

Best Publications

  • Updated Comprehensive Phylogenetic Tree of Global Human Mitochondrial DNA Variation

    Mannis van Oven;Manfred Kayser

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • DNA Commission of the International Society of Forensic Genetics (ISFG): an update of the recommendations on the use of Y-STRs in forensic analysis.

    Leonor Gusmão;J. Butler;Angel Carracedo;P. Gill

  • Evaluation of Y-chromosomal STRs: a multicenter study

    M. Kayser;A. Caglià;D. Corach;N. Fretwell

  • DNA Commission of the International Society of Forensic Genetics: recommendations on forensic analysis using Y-chromosome STRs.

    P. Gill;C. Brenner;B. Brinkmann;Bruce Budowle

  • Denisova Admixture and the First Modern Human Dispersals into Southeast Asia and Oceania

    David Reich;Nick Patterson;Martin Kircher;Frederick Delfin

  • Y-Chromosomal Diversity in Europe Is Clinal and Influenced Primarily by Geography, Rather than by Language

    Zoë H. Rosser;Tatiana Zerjal;Matthew E. Hurles;Maarja Adojaan

  • Whole-genome sequence variation, population structure and demographic history of the Dutch population

    Laurent C. Francioli;Androniki Menelaou;Sara L. Pulit;Freerk van Dijk

  • Correlation between genetic and geographic structure in Europe.

    Oscar Lao;Timothy T. Lu;Michael Nothnagel;Olaf Junge

  • Effect of sleep deprivation on the human metabolome.

    Sarah K. Davies;Joo Ern Ang;Victoria L. Revell;Ben Holmes

  • Characteristics and frequency of germline mutations at microsatellite loci from the human Y chromosome, as revealed by direct observation in father/son pairs.

    Manfred Kayser;Lutz Roewer;Minttu Hedman;Lotte Henke

  • The HIrisPlex system for simultaneous prediction of hair and eye colour from DNA

    Susan Walsh;Fan Liu;Andreas Wollstein;Leda Kovatsi

  • The effective mutation rate at Y chromosome short tandem repeats, with application to human population-divergence time.

    Lev A. Zhivotovsky;Peter A. Underhill;Cengiz Cinnioğlu;Manfred Kayser

  • Mutability of Y-chromosomal microsatellites: rates, characteristics, molecular bases and forensic implications

    Kaye N. Ballantyne;Miriam Goedbloed;Rixun Fang;Onno Schaap

  • Chromosome Y microsatellites: population genetic and evolutionary aspects.

    P. de Knijff;M. Kayser;A. Caglià;D. Corach

  • IrisPlex: A sensitive DNA tool for accurate prediction of blue and brown eye colour in the absence of ancestry information

    Susan Walsh;Fan Liu;Kaye N. Ballantyne;Mannis van Oven

  • MicroRNA markers for forensic body fluid identification obtained from microarray screening and quantitative RT-PCR confirmation.

    Dmitry Zubakov;Anton W. M. Boersma;Ying Choi;Patricia F. van Kuijk

  • Improving human forensics through advances in genetics, genomics and molecular biology

    Manfred Kayser;Peter de Knijff

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    H. Lango Allen;K. Estrada;G. Lettre;S. I. Berndt

Frequent Co-Authors

André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Albert Hofman
Albert Hofman Harvard University
Walther Parson
Walther Parson Innsbruck Medical University
Peter de Knijff
Peter de Knijff Leiden University Medical Center
Tim D. Spector
Tim D. Spector King's College London
Nicholas G. Martin
Nicholas G. Martin QIMR Berghofer Medical Research Institute
Pirro G. Hysi
Pirro G. Hysi King's College London
M. Arfan Ikram
M. Arfan Ikram Erasmus University Rotterdam
Fernando Rivadeneira
Fernando Rivadeneira Erasmus University Rotterdam
Jiali Han
Jiali Han Indiana University – Purdue University Indianapolis

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