What is he best known for?
The fields of study he is best known for:
Cahir J. O'Kane mainly focuses on Cell biology, Autophagy, PI3K/AKT/mTOR pathway, Huntingtin and Genetics.
Cahir J. O'Kane works in the field of Cell biology, focusing on Signal transduction in particular.
His Autophagy research includes elements of Parkinson's disease, Alpha-synuclein, Gene knockdown and Sirolimus.
His research in PI3K/AKT/mTOR pathway intersects with topics in Immunology, Polyglutamine tract, Neurodegeneration and Programmed cell death.
His Huntingtin study introduces a deeper knowledge of Mutant.
His biological study spans a wide range of topics, including Enhancer and Regulation of gene expression, Regulatory sequence.
His most cited work include:
- Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. (1930 citations)
- Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects (712 citations)
- Detection in situ of genomic regulatory elements in Drosophila. (672 citations)
What are the main themes of his work throughout his whole career to date?
Cahir J. O'Kane focuses on Cell biology, Genetics, Neuroscience, Gene and Autophagy.
His studies in Cell biology integrate themes in fields like Biochemistry, Mutant and Neurodegeneration.
The various areas that Cahir J. O'Kane examines in his Mutant study include Mutation and Cell.
His Neuroscience research is multidisciplinary, incorporating elements of Calyx, Anatomy and Mushroom bodies.
His study looks at the relationship between Gene and fields such as Molecular biology, as well as how they intersect with chemical problems.
His Autophagy research incorporates elements of Huntingtin, PI3K/AKT/mTOR pathway, Gene knockdown and Sirolimus.
He most often published in these fields:
- Cell biology (51.38%)
- Genetics (31.19%)
- Neuroscience (21.10%)
What were the highlights of his more recent work (between 2016-2021)?
- Endoplasmic reticulum (11.01%)
- Neuroscience (21.10%)
- Cell biology (51.38%)
In recent papers he was focusing on the following fields of study:
Cahir J. O'Kane spends much of his time researching Endoplasmic reticulum, Neuroscience, Cell biology, Axon and Hereditary spastic paraplegia.
As part of one scientific family, Cahir J. O'Kane deals mainly with the area of Neuroscience, narrowing it down to issues related to the Mushroom bodies, and often Olfactory Learning.
His research combines Neurodegeneration and Cell biology.
The study incorporates disciplines such as Reticulon, Axoplasmic transport and Mutant in addition to Axon.
His Hereditary spastic paraplegia research includes themes of Intracellular, Function and Proteasome.
In his study, Drosophila and Drosophila melanogaster is inextricably linked to Motor neuron, which falls within the broad field of Neuromuscular junction.
Between 2016 and 2021, his most popular works were:
- Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins (35 citations)
- Axonal Endoplasmic Reticulum Dynamics and Its Roles in Neurodegeneration. (13 citations)
- GAL4 Drivers Specific for Type Ib and Type Is Motor Neurons in Drosophila. (13 citations)
In his most recent research, the most cited papers focused on:
Cahir J. O'Kane mainly investigates Cell biology, Endoplasmic reticulum, Axon, Neurodegeneration and Reticulon.
His Cell biology study frequently links to adjacent areas such as Cell physiology.
The Neurodegeneration study combines topics in areas such as Phenotype and Organelle.
Cahir J. O'Kane has included themes like Ultrastructure, Protein family, Mutant and Hereditary spastic paraplegia in his Reticulon study.
Cahir J. O'Kane mostly deals with Wild type in his studies of Mutant.
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