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Molecular Biology

D-Index
54
Citations
8057
World Ranking
2345
National Ranking
1160

Research.com Recognitions

  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Michael J. Smerdon is a researcher affiliated with Washington State University in the United States. Their work primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with a particular emphasis on Molecular Biology. Their research covers various subfields, including Genetics, Cancer Research, and Plant Science.

The main topics addressed in their research include:

  • Genomics and Chromatin Dynamics
  • DNA Repair Mechanisms
  • Chromatin Remodeling and Cancer
  • Advanced Biosensing and Bioanalysis Techniques
  • Bacterial Genetics and Biotechnology
  • Carcinogens and Genotoxicity Assessment
  • Plant Genetic and Mutation Studies

Smerdon has contributed to several scientific publications. Some of their recent papers include:

  • "Distinct roles for RSC and SWI/SNF chromatin remodelers in genomic excision repair," 2021, published in Genome Research
  • "A half century of exploring DNA excision repair in chromatin," 2023, published in Journal of Biological Chemistry
  • "Versatile cell-based assay for measuring DNA alkylation damage and its repair," 2021, published in Scientific Reports
  • "Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity," 2020, published in UNC Libraries

Their frequent co-authors include:

  • John J. Wyrick
  • Wioletta Czaja
  • Peng Mao
  • Kaitlynne A. Bohm
  • Amelia J. Hodges

Smerdon has published in various scientific venues, with notable contributions to:

  • Genome Research
  • Journal of Biological Chemistry
  • Scientific Reports
  • UNC Libraries

In 2010, Michael J. Smerdon was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • The oxidative DNA lesion 8,5'-(S)-cyclo-2'-deoxyadenosine is repaired by the nucleotide excision repair pathway and blocks gene expression in mammalian cells.

    Philip J. Brooks;Dean S. Wise;David A. Berry;Joseph V. Kosmoski

  • The octadecanoid signalling pathway in plants mediates a response to ultraviolet radiation.

    Antonio Conconi;Michael J. Smerdon;Gregg A. Howe;Clarence A. Ryan

  • DNA repair and the role of chromatin structure

    Michael J. Smerdon

  • Site-specific DNA repair at the nucleosome level in a yeast minichromosome

    Michael J. Smerdon;Fritz Thoma

  • Nucleosome rearrangement in human chromatin during UV-induced DNA- reapir synthesis.

    Michael J. Smerdon;Michael W. Lieberman

  • UV-induced formation of pyrimidine dimers in nucleosome core DNA is strongly modulated with a period of 10. 3 bases

    James M. Gale;Karen A. Nissen;Michael J. Smerdon

  • Rad4-Rad23 interaction with SWI/SNF links ATP-dependent chromatin remodeling with nucleotide excision repair.

    Feng Gong;Deirdre Fahy;Michael J Smerdon

  • Suppressed catalytic activity of base excision repair enzymes on rotationally positioned uracil in nucleosomes

    Brian C. Beard;Samuel H. Wilson;Michael J. Smerdon

  • Enhanced DNA repair synthesis in hyperacetylated nucleosomes

    Brinda Ramanathan;M. J. Smerdon

  • Rpb4 and Rpb9 mediate subpathways of transcription‐coupled DNA repair in Saccharomyces cerevisiae

    Shisheng Li;Michael J. Smerdon

  • Modulation of DNA Damage and DNA Repair in Chromatin

    Michael J. Smerdon;Antonio Conconi

  • Sodium butyrate stimulates DNA repair in UV-irradiated normal and xeroderma pigmentosum human fibroblasts.

    M J Smerdon;S Y Lan;R E Calza;R Reeves

  • Chromosomal landscape of UV damage formation and repair at single-nucleotide resolution

    Peng Mao;Michael J. Smerdon;Steven A. Roberts;John J. Wyrick

  • Distribution of ultraviolet-induced DNA repair synthesis in nuclease sensitive and resistant regions of human chromatin.

    Michael J. Smerdon;Thea D. Tlsty;Michael W. Lieberman

  • ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma

    Peng Mao;Alexander J. Brown;Shingo Esaki;Svetlana Lockwood

  • Changes in nuclear protein acetylation in u.v.-damaged human cells.

    Brinda Ramanathan;Michael J. Smerdon

  • Rotational dynamics of DNA on the nucleosome surface markedly impact accessibility to a DNA repair enzyme

    John M. Hinz;Yesenia Rodriguez;Michael J. Smerdon

  • UV induced (6-4) photoproducts are distributed differently than cyclobutane dimers in nucleosomes.

    James M. Gale;Michael J. Smerdon

  • The Structural Location of DNA Lesions in Nucleosome Core Particles Determines Accessibility by Base Excision Repair Enzymes

    Yesenia Rodriguez;Michael J. Smerdon

  • Transcription-coupled repair in RNA polymerase I-transcribed genes of yeast.

    Antonio Conconi;Vyacheslav A. Bespalov;Michael J. Smerdon

Frequent Co-Authors

Michael W. Lieberman
Michael W. Lieberman Baylor College of Medicine
Raymond Reeves
Raymond Reeves Washington State University
Samuel H. Wilson
Samuel H. Wilson National Institutes of Health
Rajendra Prasad
Rajendra Prasad Amity University
Samuel H. Wilson
Samuel H. Wilson Research Triangle Park Foundation
David L. Mitchell
David L. Mitchell The University of Texas MD Anderson Cancer Center
Clarence A. Ryan
Clarence A. Ryan Washington State University
Miroslav Radman
Miroslav Radman Université Paris Cité
Piotr A. Mieczkowski
Piotr A. Mieczkowski University of North Carolina at Chapel Hill
Alan R. Lehmann
Alan R. Lehmann University of Sussex

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