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Larry M. Karnitz

Larry M. Karnitz

Mayo Clinic
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
9847
World Ranking
15696
National Ranking
6541

Larry M. Karnitz publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Larry M. Karnitz sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 99 publications — 5th percentile

5% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Larry M. Karnitz D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Larry M. Karnitz sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 54 D-Index — 22nd percentile

22% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Larry M. Karnitz is a researcher affiliated with the Mayo Clinic in the United States. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broader fields, Karnitz has focused on subfields such as Molecular Biology, Oncology, Cancer Research, Reproductive Medicine, and Pulmonary and Respiratory Medicine.

Their research explores several main topics, including:

  • DNA Repair Mechanisms
  • PARP inhibition in cancer therapy
  • Ovarian cancer diagnosis and treatment
  • Cancer, Lipids, and Metabolism
  • RNA modifications and cancer
  • Mitochondrial Function and Pathology
  • CRISPR and Genetic Engineering

Karnitz has contributed to the scientific literature with multiple publications, including studies published in notable venues such as Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Clinical Cancer Research, Cell Reports Medicine, and Nature Metabolism. Their frequent publication venues include:

  • Cancer Research (6 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (2 publications)
  • Clinical Cancer Research (2 publications)
  • Cell Reports Medicine (1 publication)
  • Nature Metabolism (1 publication)

Representative recent papers authored or co-authored by Karnitz include:

  • Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer, 2021, Cell Reports Medicine
  • Enzymatic activation of pyruvate kinase increases cytosolic oxaloacetate to inhibit the Warburg effect, 2021, Nature Metabolism
  • VLX600 Disrupts Homologous Recombination and Synergizes with PARP Inhibitors and Cisplatin by Inhibiting Histone Lysine Demethylases, 2021, Molecular Cancer Therapeutics
  • Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance, 2021, NAR Cancer
  • Repurposing Ceritinib Induces DNA Damage and Enhances PARP Inhibitor Responses in High-Grade Serous Ovarian Carcinoma, 2021, Cancer Research

Throughout their career, Karnitz has frequently collaborated with several co-authors, including:

  • Scott H. Kaufmann (13 collaborations)
  • Xiaonan Hou (9 collaborations)
  • Catherine J. Huntoon (7 collaborations)
  • S. John Weroha (7 collaborations)
  • Arun Kanakkanthara (6 collaborations)

Best Publications

  • The Rad9–Hus1–Rad1 (9–1–1) clamp activates checkpoint signaling via TopBP1

    Sinny Delacroix;Jill M. Wagner;Masahiko Kobayashi;Ken Ichi Yamamoto

  • An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function

    Bradley T. Scroggins;Kenneth Robzyk;Dongxia Wang;Monica G. Marcu

  • The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1.

    Ericka C. Busby;Dru F. Leistritz;Robert T. Abraham;Larry M. Karnitz

  • Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex.

    Edgardo R. Parrilla-Castellar;Sonnet J.H. Arlander;Larry Karnitz

  • Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events.

    J P Secrist;L A Burns;L Karnitz;G A Koretzky

  • Human Homologs of Schizosaccharomyces pombe Rad1, Hus1, and Rad9 Form a DNA Damage-responsive Protein Complex

    Elias Volkmer;Larry M. Karnitz

  • Ovarian Cancer-associated Mutations Disable Catalytic Activity of CDK12, a Kinase That Promotes Homologous Recombination Repair and Resistance to Cisplatin and Poly(ADP-ribose) Polymerase Inhibitors

    Poorval M. Joshi;Shari L. Sutor;Catherine J. Huntoon;Larry M. Karnitz

  • Effects of p56lck deficiency on the growth and cytolytic effector function of an interleukin-2-dependent cytotoxic T-cell line.

    Larry Karnitz;Shari L. Sutor;Toshihiko Torigoe;John C. Reed

  • T-cell antigen receptor ligation induces tyrosine phosphorylation of phospholipase C-gamma 1.

    J P Secrist;L Karnitz;R T Abraham

  • ATR Inhibition Broadly Sensitizes Ovarian Cancer Cells to Chemotherapy Independent of BRCA Status

    Catherine J. Huntoon;Karen S. Flatten;Andrea E. Wahner Hendrickson;Amelia M. Huehls

  • Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress.

    Sonnet J.H. Arlander;Alex K. Eapen;Benjamin T. Vroman;Robert J. McDonald

  • Molecular Pathways: Targeting ATR in Cancer Therapy

    Larry M. Karnitz;Lee Zou

  • The Bile Acid Taurochenodeoxycholate Activates a Phosphatidylinositol 3-Kinase-dependent Survival Signaling Cascade

    Christian Rust;Larry M. Karnitz;Carlos V. Paya;Jorge Moscat

  • Reconstitution and molecular analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA damage responsive checkpoint complex.

    Matthew A. Burtelow;Pia M.K. Roos-Mattjus;Matthew Rauen;Jeremy R. Babendure

  • Fc receptor stimulation of phosphatidylinositol 3-kinase in natural killer cells is associated with protein kinase C-independent granule release and cell-mediated cytotoxicity.

    Joy D. Bonnema;Larry M. Karnitz;Renee A. Schoon;Robert T. Abraham

  • Fc gamma receptor activation induces the tyrosine phosphorylation of both phospholipase C (PLC)-gamma 1 and PLC-gamma 2 in natural killer cells.

    Adrian T. Ting;Larry M. Karnitz;Renee A. Schoon;Robert T. Abraham

  • Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway.

    L M Karnitz;L A Burns;S L Sutor;J Blenis

  • Pharmacological abrogation of S-phase checkpoint enhances the anti-tumor activity of gemcitabine in vivo.

    David J. Matthews;F. Michael Yakes;Jason Chen;Michele Tadano

  • Gemcitabine-Induced Activation of Checkpoint Signaling Pathways That Affect Tumor Cell Survival

    Larry M. Karnitz;Karen S. Flatten;Jill M. Wagner;David Loegering

  • Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia cells to cytarabine

    Ruben A. Mesa;David Loegering;Heather L. Powell;Karen Flatten

Frequent Co-Authors

Scott H. Kaufmann
Scott H. Kaufmann Mayo Clinic
Robert T. Abraham
Robert T. Abraham Pfizer (United States)
B. Douglas Smith
B. Douglas Smith Johns Hopkins University
Judith E. Karp
Judith E. Karp Johns Hopkins University
David A. Loegering
David A. Loegering Mayo Clinic
Paul J. Leibson
Paul J. Leibson Mayo Clinic
Charles Erlichman
Charles Erlichman Mayo Clinic
James G. Herman
James G. Herman University of Pittsburgh
Ann L. Oberg
Ann L. Oberg Mayo Clinic
Mark R. Litzow
Mark R. Litzow Mayo Clinic

External Links

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Best Scientists Citing Larry M. Karnitz

Scott H. Kaufmann

Scott H. Kaufmann

Mayo Clinic

Publications: 51

Arthur Weiss

Arthur Weiss

University of California, San Francisco

Publications: 29

Robert T. Abraham

Robert T. Abraham

Pfizer (United States)

Publications: 27

Daniel D. Billadeau

Daniel D. Billadeau

Mayo Clinic

Publications: 25

Lee Zou

Lee Zou

Duke University

Publications: 23

Paul J. Leibson

Paul J. Leibson

Mayo Clinic

Publications: 23

Aziz Sancar

Aziz Sancar

University of North Carolina at Chapel Hill

Publications: 21

Judith E. Karp

Judith E. Karp

Johns Hopkins University

Publications: 20

David Cortez

David Cortez

Vanderbilt University

Publications: 19

Gregory J. Gores

Gregory J. Gores

Mayo Clinic

Publications: 19

Paul Workman

Paul Workman

Institute of Cancer Research

Publications: 19

Yves Pommier

Yves Pommier

National Institutes of Health

Publications: 19

Gary A. Koretzky

Gary A. Koretzky

Cornell University

Publications: 18

Junjie Chen

Junjie Chen

The University of Texas MD Anderson Cancer Center

Publications: 17

Tomas Mustelin

Tomas Mustelin

University of Washington

Publications: 17

Lawrence E. Samelson

Lawrence E. Samelson

National Institutes of Health

Publications: 16

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