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D-Index & Metrics

Genetics

D-Index
44
Citations
25025
World Ranking
4236
National Ranking
1825

Overview

Harrison Brand is affiliated with Harvard University in the United States and has a significant focus on the fields of Biochemistry, Genetics, and Molecular Biology. Their extensive research portfolio includes 188 publications primarily distributed in subfields such as Genetics (127 publications), Molecular Biology (57 publications), Pediatrics, Perinatology and Child Health (9 publications), Plant Science (8 publications), and Surgery (8 publications).

The primary topics covered in their research encompass:

  • Genomics and Rare Diseases
  • Genomic variations and chromosomal abnormalities
  • Craniofacial Disorders and Treatments
  • Cleft Lip and Palate Research
  • Genomics and Phylogenetic Studies
  • Genetics and Neurodevelopmental Disorders
  • Genetic Associations and Epidemiology

Brand has contributed to multiple research papers, including highly cited works from 2020 to 2023. Notable publications include:

  • The mutational constraint spectrum quantified from variation in 141,456 humans, 2020, Nature
  • Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism, 2020, Cell
  • A structural variation reference for medical and population genetics, 2020, Nature
  • A genomic mutational constraint map using variation in 76,156 human genomes, 2023, Nature
  • High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios, 2022, Cell

The venues where Brand frequently publishes reflect a broad engagement with the genetics research community. They have 28 publications in bioRxiv (Cold Spring Harbor Laboratory), 10 in The American Journal of Human Genetics, 8 in Nature, 6 in Genetics in Medicine, and 4 in Nature Genetics.

Collaborations constitute an important part of Brand's research activities. Frequent coauthors include:

  • Michael E. Talkowski (72 joint publications)
  • Ryan L. Collins (37 joint publications)
  • Jack Fu (32 joint publications)
  • Xuefang Zhao (31 joint publications)
  • Anne O'Donnell-Luria (26 joint publications)

Best Publications

  • The mutational constraint spectrum quantified from variation in 141,456 humans

    Konrad J. Karczewski;Laurent C. Francioli;Grace Tiao;Beryl B. Cummings

  • The mutational constraint spectrum quantified from variation in 141,456 humans

    Konrad J. Karczewski;em> ..] Laurent C. Francioli;Daniel G. MacArthur

  • Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

    F. Kyle Satterstrom;F. Kyle Satterstrom;Jack A. Kosmicki;Jiebiao Wang;Michael S. Breen

  • A structural variation reference for medical and population genetics

    Ryan L Collins;Ryan L Collins;Harrison Brand;Harrison Brand;Konrad J Karczewski;Konrad J Karczewski;Xuefang Zhao;Xuefang Zhao

  • Multi-platform discovery of haplotype-resolved structural variation in human genomes

    Mark J.P. Chaisson;Mark J.P. Chaisson;Ashley D. Sanders;Xuefang Zhao;Xuefang Zhao;Ankit Malhotra

  • Haplotype-resolved diverse human genomes and integrated analysis of structural variation.

    Peter Ebert;Peter A. Audano;Qihui Zhu;Bernardo Rodriguez-Martin

  • Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing

    Adrian Veres;Bridget S. Gosis;Qiurong Ding;Ryan Collins

  • Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9

    Pankaj Kumar Mandal;Pankaj Kumar Mandal;Leonardo Manuel Ramos Ferreira;Ryan Collins;Torsten B Meissner

  • Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

    F. Kyle Satterstrom;Jack A. Kosmicki;Jiebiao Wang;Michael S Breen;Michael S Breen

  • CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors.

    Aarathi Sugathan;Marta Biagioli;Christelle Golzio;Serkan Erdin

  • An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder.

    Donna M. Werling;Harrison Brand;Harrison Brand;Joon Yong An;Matthew R. Stone

  • Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder

    Joon Yong An;Kevin Lin;Lingxue Zhu;Donna M. Werling

  • The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies

    Claire Redin;Claire Redin;Harrison Brand;Harrison Brand;Ryan L Collins;Ryan L Collins;Tammy Kammin

  • Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly

    Tatsiana Aneichyk;Tatsiana Aneichyk;William T. Hendriks;Rachita Yadav;Rachita Yadav;David Shin

  • Mutations in DCHS1 cause mitral valve prolapse

    Ronen Durst;Ronen Durst;Kimberly Sauls;David S. Peal;Annemarieke DeVlaming

  • Defining the diverse spectrum of inversions, complex structural variation, and chromothripsis in the morbid human genome.

    Ryan L. Collins;Ryan L. Collins;Harrison Brand;Harrison Brand;Claire E. Redin;Claire E. Redin;Carrie Hanscom;Carrie Hanscom

  • Loss of δ-catenin function in severe autism

    Tychele N. Turner;Kamal Sharma;Edwin C. Oh;Yangfan P. Liu

  • SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome

    Natalie D. Shaw;Natalie D. Shaw;Harrison Brand;Harrison Brand;Zachary A. Kupchinsky;Hemant Bengani

  • A cross-disorder dosage sensitivity map of the human genome

    Ryan L. Collins;Ryan L. Collins;Joseph T. Glessner;Joseph T. Glessner;Eleonora Porcu;Eleonora Porcu;Lisa-Marie Niestroj

  • SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome (vol 49, pg 238, 2017)

    ND Shaw;H Brand;ZA Kupchinsky;H Bengani

Frequent Co-Authors

Michael E. Talkowski
Michael E. Talkowski Harvard University
Benjamin M. Neale
Benjamin M. Neale Harvard University
Konrad J. Karczewski
Konrad J. Karczewski Harvard University
Mark J. Daly
Mark J. Daly Massachusetts General Hospital
Bernie Devlin
Bernie Devlin University of Pittsburgh
Jessica Alföldi
Jessica Alföldi Broad Institute
James F. Gusella
James F. Gusella Harvard University
Daniel G. MacArthur
Daniel G. MacArthur Garvan Institute of Medical Research
Joseph T. Glessner
Joseph T. Glessner Children's Hospital of Philadelphia

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