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Jessica Alföldi

Jessica Alföldi

D-Index & Metrics

Biology and Biochemistry

D-Index
44
Citations
25888
World Ranking
19182
National Ranking
7830

Overview

Jessica Alföldi is affiliated with the Broad Institute in the United States and specializes in research predominantly within Biochemistry, Genetics, and Molecular Biology. Their body of work spans multiple interconnected subfields, including Genetics, Molecular Biology, Cancer Research, Pulmonary and Respiratory Medicine, and Ecology.

The primary focus of their research encompasses several significant topics, such as:

  • Genomics and Rare Diseases
  • Genomics and Phylogenetic Studies
  • Genomic variations and chromosomal abnormalities
  • Cancer Genomics and Diagnostics
  • Genetic Associations and Epidemiology
  • Genomics and Chromatin Dynamics
  • Genetic diversity and population structure

Jessica Alföldi has contributed extensively to scientific literature, with publications featured in various venues. The most frequent publication platforms include:

  • Nature
  • Nature Communications
  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Cell

Among their recent and notable papers are:

  • "The mutational constraint spectrum quantified from variation in 141,456 humans," 2020, Nature
  • "A structural variation reference for medical and population genetics," 2020, Nature
  • "A genomic mutational constraint map using variation in 76,156 human genomes," 2023, Nature
  • "Progressive Cactus is a multiple-genome aligner for the thousand-genome era," 2020, Nature
  • "A genome-wide mutational constraint map quantified from variation in 76,156 human genomes," 2022, bioRxiv (Cold Spring Harbor Laboratory)

Their collaborations include frequent co-authorship with several scientists, joining efforts in various publications. Notable coauthors are:

  • Laurent C. Francioli (19 coauthored works)
  • Beryl B. Cummings (19 coauthored works)
  • Konrad J. Karczewski (17 coauthored works)
  • Nicholas A. Watts (17 coauthored works)
  • Ryan L. Collins (16 coauthored works)

This compilation reflects Jessica Alföldi's research contributions, collaborations, and focus areas that are integral to ongoing developments in genomics and molecular biology at the Broad Institute and beyond.

Best Publications

  • The mutational constraint spectrum quantified from variation in 141,456 humans

    Konrad J. Karczewski;Laurent C. Francioli;Grace Tiao;Beryl B. Cummings

  • A high-resolution map of human evolutionary constraint using 29 mammals.

    Kerstin Lindblad-Toh;Manuel Garber;Or Zuk;Michael F. Lin;Michael F. Lin

  • A structural variation reference for medical and population genetics

    Ryan L Collins;Ryan L Collins;Harrison Brand;Harrison Brand;Konrad J Karczewski;Konrad J Karczewski;Xuefang Zhao;Xuefang Zhao

  • The genomic substrate for adaptive radiation in African cichlid fish

    David Brawand;David Brawand;Catherine E. Wagner;Catherine E. Wagner;Yang I. Li;Milan Malinsky;Milan Malinsky

  • The African coelacanth genome provides insights into tetrapod evolution

    Chris T. Amemiya;Chris T. Amemiya;Jessica Alfoldi;Alison P. Lee;Shaohua Fan

  • The genome of the green anole lizard and a comparative analysis with birds and mammals

    Jessica Alföldi;Federica Di Palma;Manfred Grabherr;Christina Williams

  • The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

    Ingo Braasch;Andrew R Gehrke;Jeramiah J Smith;Kazuhiko Kawasaki

  • Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators

    Daniel W. Bellott;Jennifer F. Hughes;Helen Skaletsky;Laura G. Brown

  • Progressive Cactus is a multiple-genome aligner for the thousand-genome era

    Joel Armstrong;Glenn Hickey;Mark Diekhans;Ian T. Fiddes

  • Convergent evolution of the genomes of marine mammals

    Andrew D Foote;Andrew D Foote;Yue Liu;Gregg W C Thomas;Tomáš Vinař

  • Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication.

    Miguel Carneiro;Carl Johan Rubin;Federica Di Palma;Federica Di Palma;Frank W. Albert

  • A comparative genomics multitool for scientific discovery and conservation

    Diane P. Genereux;Aitor Serres;Joel Armstrong;Jeremy Johnson

  • Genome-wide synteny through highly sensitive sequence alignment

    Manfred G. Grabherr;Pamela Russell;Miriah Meyer;Evan Mauceli

  • FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome.

    Valentin Wucher;Fabrice Legeai;Benoît Hédan;Guillaume Rizk

  • Sequencing the Mouse Y Chromosome Reveals Convergent Gene Acquisition and Amplification on Both Sex Chromosomes

    Y.Q. Shirleen Soh;Jessica Alföldi;Tatyana Pyntikova;Laura G. Brown;Laura G. Brown

  • An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts.

    Marc P. Hoeppner;Andrew Lundquist;Andrew Lundquist;Mono Pirun;Jennifer R. S. Meadows

  • A comprehensive genomic history of extinct and living elephants

    Eleftheria Palkopoulou;Eleftheria Palkopoulou;Mark Lipson;Swapan Mallick;Swapan Mallick;Svend Nielsen

  • Comparative genomics as a tool to understand evolution and disease

    Jessica Alföldi;Kerstin Lindblad-Toh;Kerstin Lindblad-Toh

  • Sequencing the Mouse Y Chromosome Reveals Convergent Gene Acquisition and Amplification on Both Sex Chromosomes

    Tatyana Pyntikova;Laura G. Brown;Tina Graves;Patrick J. Minx

  • Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators

    Jennifer F. Hughes;Helen Skaletsky;Laura G. Brown;Tatyana Pyntikova

Frequent Co-Authors

Kerstin Lindblad-Toh
Kerstin Lindblad-Toh Uppsala University
Konrad J. Karczewski
Konrad J. Karczewski Harvard University
Daniel G. MacArthur
Daniel G. MacArthur Garvan Institute of Medical Research
Federica Di Palma
Federica Di Palma Earlham Institute
Mark J. Daly
Mark J. Daly Massachusetts General Hospital
Eric S. Lander
Eric S. Lander Broad Institute
Benjamin M. Neale
Benjamin M. Neale Harvard University
Aarno Palotie
Aarno Palotie University of Helsinki
Harrison Brand
Harrison Brand Harvard University

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