World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
78
Citations
40750
World Ranking
1663
National Ranking
765

Overview

Jason D. Lieb is affiliated with the University of Chicago in the United States. Their research primarily focuses on fields within Biochemistry, Genetics, and Molecular Biology, with a particular emphasis on Molecular Biology. They have contributed to subfields including Aging, Immunology, Plant Science, and the Endocrine and Autonomic Systems.

The scientist's main research topics cover a variety of areas, including:

  • Genetics, Aging, and Longevity in Model Organisms
  • Nuclear Structure and Function
  • RNA Research and Splicing
  • Genomics and Chromatin Dynamics
  • RNA and protein synthesis mechanisms
  • Fungal and yeast genetics research
  • CRISPR and Genetic Engineering

Jason D. Lieb has authored numerous publications, with a strong presence in the UNC Libraries and Developmental Cell, as well as Circulation Research. Recent papers include:

  • Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria (2020, Developmental Cell)
  • Evidence for compensatory upregulation of expressed X-linked genes in mammals, Caenorhabditis elegans and Drosophila melanogaster (2020, UNC Libraries)
  • Zelda is differentially required for chromatin accessibility, transcription factor binding, and gene expression in the early Drosophila embryo (2020, UNC Libraries)
  • The function and regulation of the GATA factor ELT-2 in the C. elegans endoderm (2020, UNC Libraries)
  • Systematic evaluation of factors influencing ChIP-seq fidelity (2020, UNC Libraries)

Throughout their career, Jason D. Lieb has frequently collaborated with other researchers, including:

  • Sevinç Ercan
  • Kohta Ikegami
  • Paul G. Giresi
  • Daniel J. McKay
  • Sheera Adar

The scientist's work spans 50 publications in Biochemistry, Genetics and Molecular Biology, with 44 specifically in Molecular Biology. Their extensive contributions to the UNC Libraries collection, with 46 publications, indicate a substantial output in both archival and cutting-edge research contexts.

Best Publications

  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

    Ewan Birney;John A. Stamatoyannopoulos;Anindya Dutta;Roderic Guigó

  • The accessible chromatin landscape of the human genome

    Robert E. Thurman;Eric Rynes;Richard Humbert;Jeff Vierstra

  • An integrated encyclopedia of DNA elements in the human genome

    Ian Dunham;Anshul Kundaje;Shelley F. Aldred;Patrick J. Collins

  • ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

    Stephen G. Landt;Georgi K. Marinov;Anshul Kundaje;Pouya Kheradpour

  • A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

    Richard M. Myers;John Stamatoyannopoulos;Michael Snyder;Ian Dunham

  • The DNA-encoded nucleosome organization of a eukaryotic genome

    Noam Kaplan;Irene K. Moore;Yvonne Fondufe-Mittendorf;Andrea J. Gossett

  • Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project

    Mark B. Gerstein;Zhi John Lu;Eric L. Van Nostrand;Chao Cheng

  • FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin

    Paul G. Giresi;Jonghwan Kim;Ryan M. McDaniell;Vishwanath R. Iyer

  • Unlocking the Secrets of the Genome

    Susan E. Celniker;Laura A. L. Dillon;Mark B. Gerstein;Kristin C. Gunsalus

  • Promoter-specific binding of Rap1 revealed by genome-wide maps of protein–DNA association

    Jason D. Lieb;Xiaole Liu;David Botstein;Patrick O. Brown

  • Evidence for nucleosome depletion at active regulatory regions genome-wide.

    Cheol Koo Lee;Yoichiro Shibata;Bhargavi Rao;Brian D. Strahl

  • ChIP-chip: considerations for the design, analysis, and application of genome-wide chromatin immunoprecipitation experiments.

    Michael J Buck;Jason D Lieb

  • Defining functional DNA elements in the human genome

    Manolis Kellis;Barbara Wold;Michael P. Snyder;Bradley E. Bernstein

  • What are super-enhancers?

    Sebastian Pott;Jason D Lieb

  • A map of open chromatin in human pancreatic islets

    Kyle J. Gaulton;Takao Nammo;Lorenzo Pasquali;Jeremy M. Simon

  • Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity

    Lingyun Song;Zhancheng Zhang;Linda L. Grasfeder;Alan P. Boyle

  • Nucleosome dynamics define transcriptional enhancers.

    Housheng Hansen He;Clifford A. Meyer;Hyunjin Shin;Shannon T. Bailey

  • A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters.

    Gwenael Badis;Esther T. Chan;Harm van Bakel;Lourdes Pena-Castillo

  • An assessment of histone-modification antibody quality

    Thea A. Egelhofer;Aki Minoda;Aki Minoda;Sarit Klugman;Sarit Klugman;Kyungjoon Lee

  • Integrating regulatory motif discovery and genome-wide expression analysis

    Erin M. Conlon;X. Shirley Liu;Jason D. Lieb;Jun S. Liu

Frequent Co-Authors

Gregory E. Crawford
Gregory E. Crawford Duke University
Terrence S. Furey
Terrence S. Furey University of North Carolina at Chapel Hill
Vishwanath R. Iyer
Vishwanath R. Iyer The University of Texas at Austin
Ewan Birney
Ewan Birney European Molecular Biology Laboratory
Mark Gerstein
Mark Gerstein Yale University
Anshul Kundaje
Anshul Kundaje Stanford University
Michael Snyder
Michael Snyder Stanford University
Bradley E. Bernstein
Bradley E. Bernstein Broad Institute
Peggy J. Farnham
Peggy J. Farnham University of Southern California

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