D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 59 Citations 17,030 150 World Ranking 1350 National Ranking 691

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Enzyme

Melanie Ehrlich mostly deals with DNA methylation, Molecular biology, Genetics, DNA and DNA hypomethylation. Her DNA methylation study combines topics from a wide range of disciplines, such as Cancer, Satellite DNA, Methylation and Epigenetics. In her research on the topic of Methylation, Epigenomics is strongly related with RNA-Directed DNA Methylation.

Her Molecular biology research is multidisciplinary, incorporating perspectives in Heterochromatin, 5-Methylcytosine and Gene. Melanie Ehrlich has included themes like High-performance liquid chromatography and Chromatography in her DNA study. The DNA hypomethylation study combines topics in areas such as Methyltransferase and DNA methyltransferase.

Her most cited work include:

  • DNA methylation in cancer: too much, but also too little. (1199 citations)
  • Amount and distribution of 5-methylcytosine in human DNA from different types of tissues or cells (824 citations)
  • The 5-methylcytosine content of DNA from human tumors (686 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of investigation include Molecular biology, DNA methylation, DNA, Genetics and Methylation. Her research in Molecular biology intersects with topics in Somatic cell, Satellite DNA, DNMT3B, Heterochromatin and Consensus sequence. Her studies deal with areas such as Chromatin, Promoter and Epigenetics as well as DNA methylation.

Her DNA research integrates issues from 5-Methylcytosine and Binding site. Her study looks at the intersection of DNA hypomethylation and topics like Carcinogenesis with DNA demethylation. The various areas that Melanie Ehrlich examines in her Biochemistry study include Cell culture and Chromatography.

She most often published in these fields:

  • Molecular biology (51.27%)
  • DNA methylation (44.94%)
  • DNA (39.24%)

What were the highlights of her more recent work (between 2015-2021)?

  • Epigenetics (24.68%)
  • Enhancer (15.19%)
  • Gene (20.25%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Epigenetics, Enhancer, Gene, DNA methylation and Chromatin. Her Epigenetics research is classified as research in Genetics. Her study in the fields of Genome, Bacteriophage, Restriction enzyme and DNA under the domain of Genetics overlaps with other disciplines such as Delftia.

Her research ties Cancer research and DNA methylation together. The concepts of her Promoter study are interwoven with issues in Carcinogenesis, Cancer, Methylation, Tissue-Specific Gene Expression and Reporter gene. Melanie Ehrlich has researched DNA hypomethylation in several fields, including Molecular biology and MYOD1 Gene.

Between 2015 and 2021, her most popular works were:

  • DNA hypermethylation in disease: mechanisms and clinical relevance (63 citations)
  • Association of 5-hydroxymethylation and 5-methylation of DNA cytosine with tissue-specific gene expression (39 citations)
  • DNA Hypomethylation in Intragenic and Intergenic Enhancer Chromatin of Muscle-Specific Genes Usually Correlates with their Expression. (20 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

The scientist’s investigation covers issues in Chromatin, Epigenetics, DNA methylation, Promoter and Enhancer. Her Chromatin research incorporates elements of Cancer stem cell and Cell biology. Her Epigenetics study improves the overall literature in Genetics.

The study incorporates disciplines such as Carcinogenesis, Cancer, Cancer research and CpG Island Methylator Phenotype in addition to Promoter. Her work investigates the relationship between Enhancer and topics such as Regulation of gene expression that intersect with problems in Molecular biology, DNA hypomethylation and MYOD1 Gene. Her study in Gene expression is interdisciplinary in nature, drawing from both Methylation and Transdifferentiation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

DNA methylation in cancer: too much, but also too little.

Melanie Ehrlich.
Oncogene (2002)

1793 Citations

Amount and distribution of 5-methylcytosine in human DNA from different types of tissues or cells

Melanie Ehrlich;Miguel A. Gama-Sosa;Lan Hsiang Huang;Rose Marie Midgett.
Nucleic Acids Research (1982)

1337 Citations

The 5-methylcytosine content of DNA from human tumors

Miguel A. Gama-Sosa;Valerie A. Slagel;Ronald W. Trewyn;Ronald Oxenhandler.
Nucleic Acids Research (1983)

1020 Citations

5-Methylcytosine in eukaryotic DNA

Melanie Ehrlich;Richard Y.-H. Wang.
Science (1981)

947 Citations

DNA hypomethylation in cancer cells.

Melanie Ehrlich.
Epigenomics (2009)

923 Citations

Analysis of repetitive element DNA methylation by MethyLight

Daniel J. Weisenberger;Mihaela Campan;Tiffany I. Long;Myungjin Kim.
Nucleic Acids Research (2005)

776 Citations

Reduced Genomic 5-Methylcytosine Content in Human Colonic Neoplasia

Andrew P. Feinberg;Charles W. Gehrke;Kenneth C. Kuo;Melanie Ehrlich.
Cancer Research (1988)

686 Citations

Quantitative reversed-phase high performance liquid chromatographic determination of major and modified deoxyribonucleosides in DNA

Kenneth C. Kuo;Roy A. McCune;Charles W. Gehrke;Rosemarie Midgett.
Nucleic Acids Research (1980)

346 Citations

Comparison of bisulfite modification of 5-methyldeoxycytidine and deoxycytidine residues

Richard Y.-H. Wang;Charles W. Gehrke;Melanie Ehrlich.
Nucleic Acids Research (1980)

341 Citations

Hypomethylation of pericentromeric DNA in breast adenocarcinomas

Ajita Narayan;Weizhen Ji;Xian Yang Zhang;Aizen Marrogi.
International Journal of Cancer (1998)

298 Citations

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