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Immunology

D-Index
74
Citations
25523
World Ranking
2036
National Ranking
77

Overview

Francesca Aloisi is affiliated with the Istituto Superiore di Sanità in Italy. Their research primarily focuses on the interplay between infectious agents and autoimmune conditions, with a particular emphasis on multiple sclerosis (MS).

Their body of work encompasses several main fields of study:

  • Medicine
  • Immunology and Microbiology

Within these fields, Aloisi's subfields of research include:

  • Immunology
  • Pathology and Forensic Medicine
  • Oncology
  • Epidemiology
  • Infectious Diseases

The core topics addressed in Aloisi's research are:

  • Multiple Sclerosis Research Studies
  • Polyomavirus and related diseases
  • T-cell and B-cell Immunology
  • Immune Response and Inflammation
  • Herpesvirus Infections and Treatments
  • Interferon and immune responses
  • COVID-19 Clinical Research Studies

Some of the recent papers published by Aloisi include:

  • Epstein-Barr virus as a cause of multiple sclerosis: opportunities for prevention and therapy, 2023, The Lancet Neurology
  • MINI-review of Epstein-Barr virus involvement in multiple sclerosis etiology and pathogenesis, 2022, Journal of Neuroimmunology

Aloisi has collaborated frequently with several researchers, including:

  • Caterina Veroni
  • Barbara Serafini
  • Barbara Rosicarelli
  • Marco Salvetti
  • Luca Maddaloni

These collaborations appear in diverse publication venues, some of which Aloisi has frequently contributed to:

  • Journal of Neuroimmunology
  • European Urology Open Science
  • The Lancet Neurology
  • Frontiers in Immunology
  • Frontiers in Cellular Neuroscience

The research topics pursued by Aloisi mainly bridge immunological mechanisms with neurological conditions, with a recurring focus on Epstein-Barr virus as a significant factor in multiple sclerosis pathogenesis. The interaction of immune cells, especially T and B lymphocytes, and the inflammatory response within the central nervous system feature prominently in Aloisi's published work.

The scientist's contributions reveal an emphasis on understanding infectious triggers and their immunological consequences in chronic neurological diseases, grounded within a broader medical and microbiological framework.

Best Publications

  • Immune function of microglia

    Francesca Aloisi

  • Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology.

    Roberta Magliozzi;Owain Howell;Abhilash Vora;Barbara Serafini

  • Detection of Ectopic B-cell Follicles with Germinal Centers in the Meninges of Patients with Secondary Progressive Multiple Sclerosis

    Barbara Serafini;Barbara Rosicarelli;Roberta Magliozzi;Egidio Stigliano

  • Astrocytes are active players in cerebral innate immunity

    Cinthia Farina;Francesca Aloisi;Edgar Meinl

  • Lymphoid neogenesis in chronic inflammatory diseases

    Francesca Aloisi;Ricardo Pujol-Borrell

  • Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

    Owain W. Howell;Cheryl A. Reeves;Richard Nicholas;Daniele Carassiti

  • Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain

    Barbara Serafini;Barbara Rosicarelli;Diego Franciotta;Roberta Magliozzi

  • A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis

    Roberta Magliozzi;Owain W. Howell;Cheryl Reeves;Federico Roncaroli

  • Selective release of glutamate from cerebellar granule cells differentiating in culture

    V. Gallo;M. T. Ciotti;A. Coletti;F. Aloisi

  • BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma

    Markus Krumbholz;Diethilde Theil;Tobias Derfuss;Andreas Rosenwald

  • Autoradiographic localization and depolarization-induced release of acidic amino acids in differentiating cerebellar granule cell cultures.

    G. Levi;F. Aloisi;M.T. Ciotti;V. Gallo

  • Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes.

    Francesca Aloisi;Francesco Ria;Luciano Adorini

  • Production of hemolymphopoietic cytokines (IL-6, IL-8, colony-stimulating factors) by normal human astrocytes in response to IL-1 beta and tumor necrosis factor-alpha.

    Francesca Aloisi;Alessandra Carè;Giovanna Borsellino;Paolo Gallo

  • Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.

    Roberta Magliozzi;Sandra Columba-Cabezas;Barbara Serafini;Francesca Aloisi

  • Sex-based differences in autoimmune diseases.

    Elena Ortona;Marina Pierdominici;Angela Maselli;Caterina Veroni

  • Relationship of apolipoprotein E and age at onset to Parkinson disease neuropathology.

    Barbara Serafini;Barbara Rosicarelli;Roberta Magliozzi;Egidio Stigliano

  • Microglia Are More Efficient Than Astrocytes in Antigen Processing and in Th1 But Not Th2 Cell Activation

    Francesca Aloisi;Francesco Ria;Giuseppe Penna;Luciano Adorini

  • Preferential expression and function of Toll-like receptor 3 in human astrocytes.

    Cinthia Farina;Markus Krumbholz;Thomas Giese;Gunther Hartmann

  • IL-12 Production by Central Nervous System Microglia is Inhibited by Astrocytes

    F Aloisi;G Penna;J Cerase;B Menéndez Iglesias

  • Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis.

    Barbara Serafini;Sandra Columba-Cabezas;Francesca Di Rosa;Francesca Aloisi

  • B cells and multiple sclerosis.

    Diego Franciotta;Marco Salvetti;Francesco Lolli;Barbara Serafini

Frequent Co-Authors

Giulio Levi
Giulio Levi Istituto Superiore di Sanità
Luciano Adorini
Luciano Adorini Intercept Pharmaceuticals (United States)
Richard Reynolds
Richard Reynolds Imperial College London
Eliana M. Coccia
Eliana M. Coccia Istituto Superiore di Sanità
Edgar Meinl
Edgar Meinl Ludwig-Maximilians-Universität München
Giuseppe Penna
Giuseppe Penna European Institute of Oncology
Cesare Peschle
Cesare Peschle Istituto Superiore di Sanità
Hartmut Wekerle
Hartmut Wekerle Max Planck Society
Diego Franciotta
Diego Franciotta University of Pavia
Giovanna Borsellino
Giovanna Borsellino Max Delbrück Center for Molecular Medicine

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