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Philippe Saas

Philippe Saas

D-Index & Metrics

Immunology

D-Index
60
Citations
12573
World Ranking
3336
National Ranking
157

Overview

Philippe Saas is affiliated with Inserm in France, contributing extensively to the fields of Medicine, Immunology, and Microbiology. Their research spans across Immunology, Oncology, Molecular Biology, Genetics, and Epidemiology, reflecting a broad and interdisciplinary approach to biomedical sciences.

The scientist's work has focused on several key topics, including:

  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Phagocytosis and Immune Regulation
  • CAR-T Cell Therapy Research
  • Immune Cells in Cancer
  • T-cell and B-cell Immunology
  • Cancer Immunotherapy and Biomarkers

They have published articles in various scientific venues, among which the most frequent include:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Frontiers in Immunology
  • Journal of Investigative Dermatology
  • Revue du Rhumatisme
  • Annals of the Rheumatic Diseases

Some of their recent publications illustrate the scope and depth of their research:

  • "Plasmacytoid dendritic cells proliferation associated with acute myeloid leukemia: phenotype profile and mutation landscape," 2020, Haematologica
  • "Pro-Resolving Factors Released by Macrophages After Efferocytosis Promote Mucosal Wound Healing in Inflammatory Bowel Disease," 2021, Frontiers in Immunology
  • "Interplay between Liver X Receptor and Hypoxia Inducible Factor 1α Potentiates Interleukin-1β Production in Human Macrophages," 2020, Cell Reports
  • "Transcriptomic and genomic heterogeneity in blastic plasmacytoid dendritic cell neoplasms: from ontogeny to oncogenesis," 2021, Blood Advances
  • "CD28/4-1BB CD123 CAR T cells in blastic plasmacytoid dendritic cell neoplasm," 2020, Leukemia

Philippe Saas has collaborated frequently with several co-authors, including Cécile Chagué, Sylvain Perruche, Francis Bonnefoy, Étienne Daguindau, and Caroline Laheurte. These repeated collaborations indicate established research relationships in their scientific community.

Best Publications

  • Human Leukocyte Antigen‐G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+ Regulatory T Cells

    Zohair Selmani;Abderrahim Naji;Ines Zidi;Benoit Favier

  • Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?

    P Saas;P R Walker;M Hahne;A L Quiquerez

  • Role of Fas ligand (CD95L) in immune escape: the tumor cell strikes back

    P R Walker;P Saas;P Y Dietrich

  • Administration of herpes simplex–thymidine kinase–expressing donor T cells with a T-cell–depleted allogeneic marrow graft

    Pierre Tiberghien;Christophe Ferrand;Bruno Lioure;Noël Milpied

  • CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells.

    Sylvain Perruche;Pin Zhang;Yongzhong Liu;Philippe Saas

  • Inhibition of IgE-induced activation of human mast cells by IL-10.

    B. Royer;S. Varadaradjalou;P. Saas;J. J. Guillosson

  • Th1 and Th17 lymphocytes expressing CD161 are implicated in giant cell arteritis and polymyalgia rheumatica pathogenesis.

    Maxime Samson;Sylvain Audia;Jennifer Fraszczak;Malika Trad

  • Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood

    Anna Lluis;Martin Depner;Beatrice Gaugler;Philippe Saas

  • Relevance of Toll-like receptor-4 polymorphisms in renal transplantation.

    Didier Ducloux;Marina Deschamps;Maria Yannaraki;Christophe Ferrand

  • Extended diagnostic criteria for plasmacytoid dendritic cell leukaemia.

    Francine Garnache‐Ottou;Jean Feuillard;Christophe Ferrand;Sabeha Biichle

  • Role of STAT3 in CD4+CD25+FOXP3+ Regulatory Lymphocyte Generation: Implications in Graft-versus-Host Disease and Antitumor Immunity

    Jean-René Pallandre;Emilie Brillard;Gilles Créhange;Amandine Radlovic

  • CD95 (Fas/Apo-1) as a receptor governing astrocyte apoptotic or inflammatory responses: a key role in brain inflammation?

    Philippe Saas;José Boucraut;Anne-Lise Quiquerez;Valérie Schnuriger

  • Intravenous apoptotic spleen cell infusion induces a TGF-beta-dependent regulatory T-cell expansion.

    F Kleinclauss;S Perruche;E Masson;M de Carvalho Bittencourt

  • Intravenous injection of apoptotic leukocytes enhances bone marrow engraftment across major histocompatibility barriers

    Marcelo de Carvalho Bittencourt;Sylvain Perruche;Emmanuel Contassot;Stéphanie Fresnay

  • TWEAK stimulation of astrocytes and the proinflammatory consequences.

    Philippe Saas;José Boucraut;Paul R. Walker;Anne‐Lise Quiquerez

  • Tumor expression of Fas ligand (CD95L) and the consequences

    Paul R Walker;Philippe Saas;Pierre-Yves Dietrich

  • High serum vascular endothelial growth factor correlates with disease activity of spondylarthropathies.

    M. Drouart;P. Saas;M. Billot;J.‐P. Cedoz

  • Expression of the myeloid-associated marker CD33 is not an exclusive factor for leukemic plasmacytoid dendritic cells

    Francine Garnache-Ottou;Laurence Chaperot;Sabeha Biichle;Christophe Ferrand

  • Plasmacytoid dendritic cell leukaemia/lymphoma: towards a well defined entity?

    Francine Garnache-Ottou;Jean Feuillard;Philippe Saas

  • Analysis of Spontaneous Tumor-Specific CD4 T-cell Immunity in Lung Cancer Using Promiscuous HLA-DR Telomerase-Derived Epitopes: Potential Synergistic Effect with Chemotherapy Response

    Yann Godet;Elizabeth Fabre;Magalie Dosset;Michele Lamuraglia

Frequent Co-Authors

Pierre Tiberghien
Pierre Tiberghien University of Franche-Comté
Pierre-Yves Dietrich
Pierre-Yves Dietrich University of Geneva
Christophe Borg
Christophe Borg Centre Hospitalier Universitaire de Besançon
Jean Feuillard
Jean Feuillard University of Limoges
Laurent Lagrost
Laurent Lagrost Grenoble Alpes University
Elizabeth Macintyre
Elizabeth Macintyre Necker-Enfants Malades Hospital
Michel Arock
Michel Arock École Normale Supérieure Paris-Saclay
Olivier Micheau
Olivier Micheau University of Burgundy

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