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Zachary F. Mainen

Zachary F. Mainen

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Neuroscience
Portugal
2022

D-Index & Metrics

Neuroscience

D-Index
60
Citations
20272
World Ranking
3767
National Ranking
7

Research.com Recognitions

  • 2022 - Research.com Neuroscience in Portugal Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Zachary F. Mainen is affiliated with the Champalimaud Foundation in Portugal. Their research primarily focuses on neuroscience with a significant emphasis on cognitive neuroscience, cellular and molecular neuroscience, and sensory systems. The scientist has contributed to the understanding of neural dynamics and brain function, olfactory and sensory function studies, memory and neural mechanisms, neuroendocrine regulation and behavior, neurobiology and insect physiology research, advanced chemical sensor technologies, and neural and behavioral psychology studies.

Mainen has an extensive publication record with frequent contributions to venues such as bioRxiv (Cold Spring Harbor Laboratory), eLife, Neuron, Nature, and Zenodo (CERN European Organization for Nuclear Research).

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Neuron
  • Nature
  • Zenodo (CERN European Organization for Nuclear Research)

Their recent papers include the following:

  • Standardized and reproducible measurement of decision-making in mice, 2021, eLife
  • Spatial maps in piriform cortex during olfactory navigation, 2021, Nature
  • Phasic Activation of Dorsal Raphe Serotonergic Neurons Increases Pupil Size, 2020, Current Biology
  • Inference-Based Decisions in a Hidden State Foraging Task: Differential Contributions of Prefrontal Cortical Areas, 2020, Neuron
  • A Brain-Wide Map of Neural Activity during Complex Behaviour, 2023, bioRxiv (Cold Spring Harbor Laboratory)

Frequent coauthors in their research include Anne K. Churchland, Fanny Cazettes, Niccolò Bonacchi, Matteo Carandini, and Guido T. Meijer.

  • Anne K. Churchland
  • Fanny Cazettes
  • Niccolò Bonacchi
  • Matteo Carandini
  • Guido T. Meijer

Zachary F. Mainen's work explores various dimensions of neuroscience, including the measurement and analysis of decision-making behaviors, spatial mapping in sensory cortices, and the neural basis of pupil size modulation. Their investigations cover multiple scales from cellular and molecular mechanisms to complex cognitive functions.

Mainen holds membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Reliability of spike timing in neocortical neurons

    Zachary F. Mainen;Terrence J. Sejnowski;Terrence J. Sejnowski

  • Influence of dendritic structure on firing pattern in model neocortical neurons

    Zachary F. Mainen;Terrence J. Sejnowski;Terrence J. Sejnowski

  • Neural correlates, computation and behavioural impact of decision confidence

    Adam Kepecs;Naoshige Uchida;Naoshige Uchida;Hatim A. Zariwala;Hatim A. Zariwala;Zachary F. Mainen;Zachary F. Mainen

  • Speed and accuracy of olfactory discrimination in the rat

    Naoshige Uchida;Zachary F Mainen

  • Synthesis of Models for Excitable Membranes, Synaptic Transmission and Neuromodulation Using a Common Kinetic Formalism

    Alain Destexhe;Zachary F. Mainen;Terrence J. Sejnowski;Terrence J. Sejnowski

  • Demixed principal component analysis of neural population data

    Dmitry Kobak;Wieland Brendel;Wieland Brendel;Christos Constantinidis;Claudia E. Feierstein

  • An efficient method for computing synaptic conductances based on a kinetic model of receptor binding

    A. Destexhe;Z. F. Mainen;T. J. Sejnowski

  • Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice

    Daniel Huber;Daniel Huber;Leopoldo Petreanu;Leopoldo Petreanu;Nima Ghitani;Sachin P. Ranade

  • A model of spike initiation in neocortical pyramidal neurons.

    Zachary F. Mainen;Zachary F. Mainen;Jasdan Joerges;John R. Huguenard;Terrence J. Sejnowski;Terrence J. Sejnowski

  • LTP mechanisms: from silence to four-lane traffic

    Roberto Malinow;Zachary F Mainen;Yasunori Hayashi

  • Estimating intracellular calcium concentrations and buffering without wavelength ratioing.

    M. Maravall;Z.F. Mainen;B.L. Sabatini;K. Svoboda

  • EARLY EVENTS IN OLFACTORY PROCESSING

    Rachel I. Wilson;Zachary F. Mainen

  • The Sniff as a Unit of Olfactory Processing

    Adam Kepecs;Naoshige Uchida;Zachary F. Mainen

  • Synaptic calcium transients in single spines indicate that NMDA receptors are not saturated.

    Zachary F. Mainen;Roberto Malinow;Karel Svoboda

  • Confidence as Bayesian Probability: From Neural Origins to Behavior.

    Florent Meyniel;Mariano Sigman;Zachary F. Mainen

  • A computational framework for the study of confidence in humans and animals

    Adam Kepecs;Zachary F. Mainen

  • Big behavioral data: psychology, ethology and the foundations of neuroscience

    Alex Gomez-Marin;Joseph J Paton;Adam R Kampff;Rui M Costa

  • Representation of Spatial Goals in Rat Orbitofrontal Cortex

    Claudia E. Feierstein;Claudia E. Feierstein;Michael C. Quirk;Naoshige Uchida;Dara L. Sosulski

  • Neural antecedents of self-initiated actions in secondary motor cortex

    Masayoshi Murakami;M Inês Vicente;Gil M Costa;Zachary F Mainen

  • Odor Representations in Olfactory Cortex: Distributed Rate Coding and Decorrelated Population Activity

    Keiji Miura;Zachary F. Mainen;Naoshige Uchida;Naoshige Uchida

Frequent Co-Authors

Naoshige Uchida
Naoshige Uchida Harvard University
Karel Svoboda
Karel Svoboda Allen Institute
Terrence J. Sejnowski
Terrence J. Sejnowski Salk Institute for Biological Studies
Adam Kepecs
Adam Kepecs Washington University in St. Louis
Alexandre Pouget
Alexandre Pouget University of Geneva
Anthony M. Zador
Anthony M. Zador Cold Spring Harbor Laboratory
Anne K. Churchland
Anne K. Churchland University of California, Los Angeles
Johan N. Lundström
Johan N. Lundström Karolinska Institute
Roberto Malinow
Roberto Malinow University of California, San Diego
Alain Destexhe
Alain Destexhe Centre national de la recherche scientifique, CNRS

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