Tse-Hua Tan

Overview

Best Publications

• Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

  C A Finlay;P W Hinds;T H Tan;D Eliyahu

  1504
  Citations

• The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation.

  Yi-Rong Chen;Xiaoping Wang;Dennis Templeton;Roger J. Davis

  1221
  Citations

• Persistent Activation of c-Jun N-terminal Kinase 1 (JNK1) in γ Radiation-induced Apoptosis

  Yi Rong Chen;Christian F. Meyer;Tse Hua Tan

  628
  Citations

• Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin

  Yi Rong Chen;Tse Hua Tan

  539
  Citations

• Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism.

  Rong Yu;Chi Chen;Yin Yuan Mo;Vidya Hebbar

  413
  Citations

• Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product

  Steven Ruben;Harry Poteat;Tse-Hua Tan;Kyoshi Kawakami

  380
  Citations

• Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade.

  Mickey C.T. Hu;Wan R. Qiu;Xiaoping Wang;Christian F. Meyer

  308
  Citations

• Molecular Mechanisms of c-Jun N-terminal Kinase-mediated Apoptosis Induced by Anticarcinogenic Isothiocyanates *

  Y.-R. Chen;W. Wang;A.-N. T. Kong;T.-H. Tan

  306
  Citations

• Activation of the Hematopoietic Progenitor Kinase-1 (HPK1)-dependent, Stress-activated c-Jun N-terminal Kinase (JNK) Pathway by Transforming Growth Factor β (TGF-β)-activated Kinase (TAK1), a Kinase Mediator of TGF β Signal Transduction

  Wenfu Wang;Guisheng Zhou;Mickey C.-T. Hu;Zhengbin Yao

  299
  Citations

• Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4

  Xiaohong Zhang;Yukiyasu Ozawa;Heehyoung Lee;Yu-Der Wen

  294
  Citations

• DUSPs, to MAP kinases and beyond

  Ching-Yu Huang;Tse-Hua Tan;Tse-Hua Tan

  292
  Citations

• The c-Jun N-terminal kinase pathway and apoptotic signaling (review).

  Chen Yr;Tan Th

  276
  Citations

• Activation of caspase-3 and c-Jun NH2-terminal kinase-1 signaling pathways in tamoxifen-induced apoptosis of human breast cancer cells.

  Sandhya Mandlekar;Rong Yu;Tse-Hua Tan;Ah-Ng Tony Kong

  269
  Citations

• The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65.

  Paritosh Ghosh;Tse Hua Tan;Nancy R. Rice;Antonio Sica

  267
  Citations

• p38 Mitogen-activated Protein Kinase Negatively Regulates the Induction of Phase II Drug-metabolizing Enzymes That Detoxify Carcinogens

  Rong Yu;Sandhya Mandlekar;Wei Lei;William E. Fahl

  256
  Citations

• Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion.

  Hsin-Sheng Yang;Connie P. Matthews;Timothy Clair;Qing Wang

  247
  Citations

• A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway.

  Zhengbin Yao;Guisheng Zhou;Xuhong Sunny Wang;Amy Brown

  246
  Citations

• Activation of mitogen-activated protein kinases by green tea polyphenols: potential signaling pathways in the regulation of antioxidant-responsive element-mediated phase II enzyme gene expression.

  R Yu;J J Jiao;J L Duh;K Gudehithlu

  237
  Citations

• Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase.

  Xuhong Sunny Wang;K. Diener;D. Jannuzzi;D. Trollinger

  221
  Citations

• Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells

  Alexander A Shtil;Sandhya Mandlekar;Rong Yu;Robert J Walter

  218
  Citations