D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 80 Citations 38,446 181 World Ranking 2505 National Ranking 1349

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His primary scientific interests are in Cell biology, Gene, Stem cell, Tumor Protein p73 and Carcinogenesis. His Cell biology research incorporates themes from Mitotic spindle assembly checkpoint, Spindle checkpoint, Mitotic spindle checkpoint, Kinetochore and Morphogenesis. His biological study spans a wide range of topics, including Membrane protein, Molecular biology, DNA damage and Neuroblastoma.

His Stem cell study incorporates themes from Immunology, Germline and Adult stem cell. He interconnects Suppressor, Cancer research and Candidate gene in the investigation of issues within Tumor Protein p73. In Carcinogenesis, Frank McKeon works on issues like Pathology, which are connected to Fallopian tube, Serous Tubal Intraepithelial Carcinoma and Serous carcinoma.

His most cited work include:

  • p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development (1892 citations)
  • p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. (1793 citations)
  • Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. (1503 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Cell biology, Stem cell, Pathology, Cancer research and Cancer. His research integrates issues of Apoptosis, Biochemistry, Binding site and Transcription factor in his study of Cell biology. His biological study deals with issues like Calcineurin, which deal with fields such as Phosphatase, Cyclosporin a and Signal transduction.

He has researched Stem cell in several fields, including Cloning, Cellular differentiation, Adult stem cell and Immunology. Many of his research projects under Pathology are closely connected to Immunophenotyping with Immunophenotyping, tying the diverse disciplines of science together. His Cancer research research also works with subjects such as

  • Carcinogenesis which intersects with area such as Mutation,
  • Gene that intertwine with fields like Molecular biology.

He most often published in these fields:

  • Cell biology (35.53%)
  • Stem cell (29.95%)
  • Pathology (31.47%)

What were the highlights of his more recent work (between 2016-2021)?

  • Stem cell (29.95%)
  • Cancer research (21.32%)
  • Pathology (31.47%)

In recent papers he was focusing on the following fields of study:

Frank McKeon mainly focuses on Stem cell, Cancer research, Pathology, Lung and Cloning. Stem cell is a subfield of Cell biology that Frank McKeon explores. His research in Cell biology is mostly focused on Autologous transplantation.

His Cancer research research includes elements of Cancer, Genetic model, Transcription factor, Resistant cancer and Serous ovarian cancer. His work carried out in the field of Lung brings together such families of science as Inflammation, COPD, Cystic fibrosis and Circadian rhythm. His study looks at the intersection of Cloning and topics like Biopsy with Cell culture, Somatic cell, Survival rate, Clinical significance and Malignancy.

Between 2016 and 2021, his most popular works were:

  • Iron addiction: a novel therapeutic target in ovarian cancer (109 citations)
  • Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis. (18 citations)
  • A Summary of the 2016 James W. Freston Conference of the American Gastroenterological Association: Intestinal Metaplasia in the Esophagus and Stomach: Origins, Differences, Similarities and Significance (8 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

Frank McKeon spends much of his time researching Stem cell, Cloning, Cell biology, Autologous transplantation and Adult stem cell. Stem cell connects with themes related to Pathology in his study. His work is dedicated to discovering how Cloning, Biopsy are connected with Gastroenterology and other disciplines.

His biological study focuses on Regenerative medicine. His research in Autologous transplantation tackles topics such as Drug discovery which are related to areas like Epithelium, Somatic evolution in cancer and Organoid. His Adult stem cell research incorporates themes from Dysplasia, Intestinal metaplasia and Barrett's esophagus.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.

Annie Yang;Mourad Kaghad;Yunmei Wang;Emily Gillett.
Molecular Cell (1998)

2633 Citations

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

Annie Yang;Ronen Schweitzer;Deqin Sun;Mourad Kaghad.
Nature (1999)

2622 Citations

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers.

Mourad Kaghad;Helene Bonnet;Annie Yang;Laurent Creancier.
Cell (1997)

2275 Citations

p63 identifies keratinocyte stem cells

Graziella Pellegrini;Elena Dellambra;Osvaldo Golisano;Enrica Martinelli.
Proceedings of the National Academy of Sciences of the United States of America (2001)

1591 Citations

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD.

Hong Gang Wang;Nuzhat Pathan;Iryna M. Ethell;Stanislaw Krajewski.
Science (1999)

1473 Citations

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

Annie Yang;Nancy Walker;Roderick Bronson;Mourad Kaghad.
Nature (2000)

1264 Citations

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

Elsa Renee Flores;Kenneth Y Tsai;Denise Crowley;Denise Crowley;Shomit Sengupta;Shomit Sengupta.
Nature (2002)

997 Citations

A candidate precursor to serous carcinoma that originates in the distal fallopian tube.

Y Lee;A Miron;R Drapkin;M R Nucci.
The Journal of Pathology (2007)

961 Citations

p63 Is Essential for the Proliferative Potential of Stem Cells in Stratified Epithelia

Makoto Senoo;Filipa Pinto;Christopher P. Crum;Frank McKeon.
Cell (2007)

928 Citations

Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins.

Frank D. McKeon;Marc W. Kirschner;Daniel Caput.
Nature (1986)

898 Citations

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