His primary scientific interests are in Cell biology, Gene, Stem cell, Tumor Protein p73 and Carcinogenesis. His Cell biology research incorporates themes from Mitotic spindle assembly checkpoint, Spindle checkpoint, Mitotic spindle checkpoint, Kinetochore and Morphogenesis. His biological study spans a wide range of topics, including Membrane protein, Molecular biology, DNA damage and Neuroblastoma.
His Stem cell study incorporates themes from Immunology, Germline and Adult stem cell. He interconnects Suppressor, Cancer research and Candidate gene in the investigation of issues within Tumor Protein p73. In Carcinogenesis, Frank McKeon works on issues like Pathology, which are connected to Fallopian tube, Serous Tubal Intraepithelial Carcinoma and Serous carcinoma.
His scientific interests lie mostly in Cell biology, Stem cell, Pathology, Cancer research and Cancer. His research integrates issues of Apoptosis, Biochemistry, Binding site and Transcription factor in his study of Cell biology. His biological study deals with issues like Calcineurin, which deal with fields such as Phosphatase, Cyclosporin a and Signal transduction.
He has researched Stem cell in several fields, including Cloning, Cellular differentiation, Adult stem cell and Immunology. Many of his research projects under Pathology are closely connected to Immunophenotyping with Immunophenotyping, tying the diverse disciplines of science together. His Cancer research research also works with subjects such as
Frank McKeon mainly focuses on Stem cell, Cancer research, Pathology, Lung and Cloning. Stem cell is a subfield of Cell biology that Frank McKeon explores. His research in Cell biology is mostly focused on Autologous transplantation.
His Cancer research research includes elements of Cancer, Genetic model, Transcription factor, Resistant cancer and Serous ovarian cancer. His work carried out in the field of Lung brings together such families of science as Inflammation, COPD, Cystic fibrosis and Circadian rhythm. His study looks at the intersection of Cloning and topics like Biopsy with Cell culture, Somatic cell, Survival rate, Clinical significance and Malignancy.
Frank McKeon spends much of his time researching Stem cell, Cloning, Cell biology, Autologous transplantation and Adult stem cell. Stem cell connects with themes related to Pathology in his study. His work is dedicated to discovering how Cloning, Biopsy are connected with Gastroenterology and other disciplines.
His biological study focuses on Regenerative medicine. His research in Autologous transplantation tackles topics such as Drug discovery which are related to areas like Epithelium, Somatic evolution in cancer and Organoid. His Adult stem cell research incorporates themes from Dysplasia, Intestinal metaplasia and Barrett's esophagus.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.
Annie Yang;Mourad Kaghad;Yunmei Wang;Emily Gillett.
Molecular Cell (1998)
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
Annie Yang;Ronen Schweitzer;Deqin Sun;Mourad Kaghad.
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers.
Mourad Kaghad;Helene Bonnet;Annie Yang;Laurent Creancier.
p63 identifies keratinocyte stem cells
Graziella Pellegrini;Elena Dellambra;Osvaldo Golisano;Enrica Martinelli.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD.
Hong Gang Wang;Nuzhat Pathan;Iryna M. Ethell;Stanislaw Krajewski.
p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
Annie Yang;Nancy Walker;Roderick Bronson;Mourad Kaghad.
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
Elsa Renee Flores;Kenneth Y Tsai;Denise Crowley;Denise Crowley;Shomit Sengupta;Shomit Sengupta.
A candidate precursor to serous carcinoma that originates in the distal fallopian tube.
Y Lee;A Miron;R Drapkin;M R Nucci.
The Journal of Pathology (2007)
p63 Is Essential for the Proliferative Potential of Stem Cells in Stratified Epithelia
Makoto Senoo;Filipa Pinto;Christopher P. Crum;Frank McKeon.
Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins.
Frank D. McKeon;Marc W. Kirschner;Daniel Caput.
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: