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Neuroscience

D-Index
67
Citations
21476
World Ranking
2841
National Ranking
75

Overview

Graham Knott is affiliated with the École Polytechnique Fédérale de Lausanne in Switzerland. Their research spans multiple fields centered around medicine, neuroscience, and biochemistry, genetics, and molecular biology, where they have contributed to significant areas of study in neuroscience and molecular biology.

The main areas of study for Knott include:

  • Medicine
  • Neuroscience
  • Biochemistry, Genetics and Molecular Biology

The subfields within these broader topics are focused on:

  • Cellular and Molecular Neuroscience
  • Molecular Biology
  • Neurology
  • Cognitive Neuroscience
  • Cell Biology

Knott's research topics frequently revolve around:

  • Parkinson's Disease Mechanisms and Treatments
  • Neural dynamics and brain function
  • Neuroscience and Neuropharmacology Research
  • Urinary Tract Infections Management
  • Urinary Bladder and Prostate Research
  • Photoreceptor and optogenetics research
  • Cellular transport and secretion

The scientist has authored several notable papers, including:

  • The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration (2020, Proceedings of the National Academy of Sciences)
  • Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease (2020, Cell Metabolism)
  • Mitofusin-2 in the Nucleus Accumbens Regulates Anxiety and Depression-like Behaviors Through Mitochondrial and Neuronal Actions (2020, Biological Psychiatry)
  • Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection (2021, eLife)
  • ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels (2022, Nature Communications)

Frequent co-authors contributing to their collaborative work are:

  • Jérôme Blanc
  • Catherine Maclachlan
  • Kunal Sharma
  • Vivek V. Thacker
  • John D. McKinney

The venues in which Knott has frequently published include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • eLife
  • Science Advances
  • Communications Biology

Best Publications

  • Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex

    Joshua T. Trachtenberg;Brian E. Chen;Graham W. Knott;Guoping Feng

  • Transient and Persistent Dendritic Spines in the Neocortex In Vivo

    Anthony J.G.D. Holtmaat;Joshua T. Trachtenberg;Linda Wilbrecht;Gordon M. Shepherd

  • Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window

    Anthony Holtmaat;Anthony Holtmaat;Tobias Bonhoeffer;David K Chow;Jyoti Chuckowree

  • Serial section scanning electron microscopy of adult brain tissue using focused ion beam milling.

    Graham Knott;Herschel Marchman;David Wall;Ben Lich

  • Experience-dependent and cell-type-specific spine growth in the neocortex.

    Anthony Holtmaat;Linda Wilbrecht;Graham W. Knott;Egbert Welker

  • Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period.

    Bidisha Chattopadhyaya;Graziella Di Cristo;Hiroyuki Higashiyama;Graham W. Knott

  • The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration

    Anne-Laure Mahul-Mellier;Johannes Burtscher;Niran Maharjan;Laura Weerens

  • Spine growth precedes synapse formation in the adult neocortex in vivo.

    Graham W Knott;Anthony Holtmaat;Linda Wilbrecht;Egbert Welker

  • Formation of dendritic spines with GABAergic synapses induced by whisker stimulation in adult mice.

    Graham W. Knott;Charles Quairiaux;Christel Genoud;Egbert Welker

  • Synaptic proximity enables NMDAR signalling to promote brain metastasis

    Qiqun Zeng;Iacovos P. Michael;Peng Zhang;Sadegh Saghafinia

  • Cell Type-Specific Structural Plasticity of Axonal Branches and Boutons in the Adult Neocortex

    Vincenzo De Paola;Anthony Holtmaat;Graham Knott;Sen Song

  • Ultrastructural analysis of adult mouse neocortex comparing aldehyde perfusion with cryo fixation

    Natalya Korogod;Carl C H Petersen;Graham W Knott

  • GAD67-Mediated GABA Synthesis and Signaling Regulate Inhibitory Synaptic Innervation in the Visual Cortex

    Bidisha Chattopadhyaya;Bidisha Chattopadhyaya;Graziella Di Cristo;Cai Zhi Wu;Graham Knott

  • Connexin 30 sets synaptic strength by controlling astroglial synapse invasion

    Ulrike Pannasch;Dominik Freche;Glenn Dallérac;Grégory Ghézali

  • Plasticity of Astrocytic Coverage and Glutamate Transporter Expression in Adult Mouse Cortex

    Christel Genoud;Charles Quairiaux;Pascal Steiner;Pascal Steiner;Harald Hirling

  • Rapid Functional Maturation of Nascent Dendritic Spines

    Karen Zito;Volker Scheuss;Graham Knott;Travis Hill

  • Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease.

    Juliette Le Douce;Marianne Maugard;Julien Veran;Julien Veran;Marco Matos;Marco Matos

  • The relationship between PSD-95 clustering and spine stability in vivo.

    Michele Cane;Bohumil Maco;Graham Knott;Anthony Holtmaat

  • Induction of Spine Growth and Synapse Formation by Regulation of the Spine Actin Cytoskeleton

    Karen Zito;Graham Knott;Gordon M.G. Shepherd;Shirish Shenolikar

  • PSD-95 promotes synaptogenesis and multiinnervated spine formation through nitric oxide signaling

    Irina Nikonenko;Irina Nikonenko;Bernadett Boda;Sylvain Steen;Graham Knott;Graham Knott

Frequent Co-Authors

Norman R. Saunders
Norman R. Saunders Monash University
Katarzyna M. Dziegielewska
Katarzyna M. Dziegielewska University of Melbourne
Anthony Holtmaat
Anthony Holtmaat University of Geneva
Egbert Welker
Egbert Welker University of Lausanne
Karel Svoboda
Karel Svoboda Allen Institute
Carl C. H. Petersen
Carl C. H. Petersen École Polytechnique Fédérale de Lausanne
Linda Wilbrecht
Linda Wilbrecht University of California, Berkeley
Zoltán Molnár
Zoltán Molnár University of Oxford
Joshua T. Trachtenberg
Joshua T. Trachtenberg University of California, Los Angeles
Mark D. Habgood
Mark D. Habgood Monash University

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