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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
14269
World Ranking
10760
National Ranking
4674

Overview

Wei-Jen Tang is affiliated with the University of Chicago in the United States and conducts research primarily within the field of Biochemistry, Genetics and Molecular Biology. Their work encompasses several subfields including Molecular Biology, Food Science, Nutrition and Dietetics, Physiology, and Oncology.

The researcher's main topics of study include:

  • Proteins in Food Systems
  • Protein Structure and Dynamics
  • Alzheimer's disease research and treatments
  • Enzyme Structure and Function
  • Polysaccharides and Plant Cell Walls
  • Microbial Metabolites in Food Biotechnology
  • Trace Elements in Health

Wei-Jen Tang has contributed to multiple publication venues, with frequent appearances in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • SSRN Electronic Journal
  • Food Research International
  • Food Hydrocolloids
  • Journal of Molecular Biology

The recent papers authored or co-authored by Wei-Jen Tang include:

  • "Plant-based meat: The influence on texture by protein-polysaccharide interactions and processing techniques," published in 2025 in Food Research International
  • "Effect of chitosan with different molecular weights on the freeze-thaw stability of gluten protein: Protein structures, functional characteristics, and cryo-protective mechanism," published in 2024 in Food Hydrocolloids

Additional papers linked to their coauthors but not directly authored by Wei-Jen Tang are:

  • "Degradation of Alzheimer's Amyloid-β by a Catalytically Inactive Insulin-Degrading Enzyme," 2021, Journal of Molecular Biology
  • "Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition," 2022, Nature Communications
  • "Pseudomonas aeruginosa exoenzyme Y directly bundles actin filaments," 2020, Journal of Biological Chemistry

Wei-Jen Tang frequently collaborates with several co-authors, including:

  • Jordan M Mancl
  • Wenguang Liang
  • Minglei Zhao
  • Jianfei He
  • Hui Wei

Best Publications

  • Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits

    Wei Jen Tang;Alfred G. Gilman

  • Adenylyl cyclase amino acid sequence: possible channel- or transporter-like structure.

    John Krupinski;Françoise Coussen;Françoise Coussen;Heather A. Bakalyar;Wei Jen Tang

  • Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.

    Chester L. Drum;Shui-Zhong Yan;Joel Bard;Yue-Quan Shen

  • Expression and characterization of calmodulin-activated (type I) adenylylcyclase

    Wei Jen Tang;John Krupinski;Alfred G. Gilman

  • Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2.

    Salvatore Papa;Francesca Zazzeroni;Concetta Bubici;Shanthi Jayawardena

  • Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.

    Ronald Taussig;Wei Jen Tang;John R. Hepler;Alfred G. Gilman

  • Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism

    Yuequan Shen;Andrzej Joachimiak;Marsha Rich Rosner;Wei-Jen Tang

  • Molecular cloning and characterization of a Ca2+/calmodulin-insensitive adenylyl cyclase from rat brain.

    Paul G. Feinstein;Karen A. Schrader;Heather A. Bakalyar;Wei Jen Tang

  • Catalytic mechanism and regulation of mammalian adenylyl cyclases.

    Wei-Jen Tang;James H. Hurley

  • Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones

    Juan Pablo Maianti;Amanda McFedries;Zachariah H. Foda;Ralph Kleiner

  • Activation of the polyomavirus enhancer by a murine activator protein 1 (AP1) homolog and two contiguous proteins.

    Mark E. Martin;Jacques Piette;Moshe Yaniv;Wei-Jen Tang

  • Construction of a soluble adenylyl cyclase activated by Gs alpha and forskolin

    Wei Jen Tang;Alfred G. Gilman

  • Bacillus anthracis Edema Toxin Causes Extensive Tissue Lesions and Rapid Lethality in Mice

    Aaron M. Firoved;Georgina F. Miller;Mahtab Moayeri;Rahul Kakkar

  • Amyloid β-degrading cryptidases : insulin degrading enzyme, presequence peptidase, and neprilysin

    Enrico Malito;Raymond E. Hulse;Wei-Jen Tang

  • Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling.

    Silvia Rossi Paccani;Fiorella Tonello;Raffaella Ghittoni;Mariarita Natale

  • Chemical screening by mass spectrometry to identify inhibitors of anthrax lethal factor.

    Dal Hee Min;Wei Jen Tang;Milan Mrksich

  • Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme

    Min Ren;Qing Guo;Liang Guo;Martin Lenz

  • Two Cytoplasmic Domains of Mammalian Adenylyl Cyclase Form a GSα- and Forskolin-activated Enzyme in Vitro

    Shui-Zhong Yan;David Hahn;Zhi-Hui Huang;Wei-Jen Tang

  • Truncation and alanine-scanning mutants of type I adenylyl cyclase.

    Wei-Jen Tang;Marian Stanzel;Alfred G. Gilman

  • Phosphorylation of FADD at Serine 194 by CKIα Regulates Its Nonapoptotic Activities

    Elizabeth C. Alappat;Christine Feig;Benjamin Boyerinas;Jörg Volkland

Frequent Co-Authors

Stephen H. Leppla
Stephen H. Leppla National Institutes of Health
Roland Seifert
Roland Seifert Hannover Medical School
Marsha Rich Rosner
Marsha Rich Rosner University of Chicago
Alfred G. Gilman
Alfred G. Gilman The University of Texas Southwestern Medical Center
Milan Mrksich
Milan Mrksich Northwestern University
Burkhard König
Burkhard König University of Regensburg
Jan Florián
Jan Florián Loyola University Chicago
Bart Staels
Bart Staels University of Lille
Anthony A. Kossiakoff
Anthony A. Kossiakoff University of Chicago
Mahtab Moayeri
Mahtab Moayeri National Institutes of Health

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