Randall W. King mainly investigates Cell biology, Biochemistry, Mitosis, Ubiquitin and Proteasome. His Cell biology research is multidisciplinary, incorporating elements of Chromosome segregation, Biochemical switches in the cell cycle, Maturation promoting factor, Cleavage furrow and Cdc20 Proteins. His Cdc20 Proteins research is multidisciplinary, relying on both Cyclin A2, Cyclin B, Cyclin A, Anaphase-promoting complex and Cyclin D.
His Mitosis research includes themes of Nondisjunction, Anaphase, Cytokinesis and Cyclin. His work in Ubiquitin ligase, Ubiquitin-conjugating enzyme and Deubiquitinating enzyme is related to Ubiquitin. Randall W. King has researched Ubiquitin-conjugating enzyme in several fields, including Protein ubiquitination, Cell culture, Protein degradation and Cyclin B1.
His scientific interests lie mostly in Cell biology, Biochemistry, Mitosis, Proteasome and Ubiquitin. The various areas that Randall W. King examines in his Cell biology study include Chromosome segregation, Spindle checkpoint, Anaphase-promoting complex, Cyclin B1 and Cell cycle. His research integrates issues of Metaphase, APC/C activator protein CDH1 and Cdc20 Proteins in his study of Anaphase-promoting complex.
The Mitosis study combines topics in areas such as Spindle apparatus, Mitotic exit, Anaphase, CDC20 and Cyclin-dependent kinase. His Proteasome research incorporates elements of Deubiquitinating enzyme, Protein degradation, Proteolysis and Proteasome activity. His study in Ubiquitin is interdisciplinary in nature, drawing from both Xenopus and Enzyme.
Cell biology, Ubiquitin, Ubiquitin ligase, Spindle checkpoint and Anaphase-promoting complex are his primary areas of study. His Mitosis study, which is part of a larger body of work in Cell biology, is frequently linked to Selective modulation, bridging the gap between disciplines. The concepts of his Mitosis study are interwoven with issues in Cell cycle checkpoint and Mitotic exit.
His research in Ubiquitin intersects with topics in Xenopus, Enzyme and Proteasome. His studies deal with areas such as Cell cycle, Cell Cycle Protein and Receptor tyrosine kinase as well as Spindle checkpoint. His biological study spans a wide range of topics, including APC/C activator protein CDH1, CDC20 and Cyclin B1.
His primary scientific interests are in Proteasome, Ubiquitin, Ubiquitin ligase, Deubiquitinating enzyme and Cell biology. His Proteasome study incorporates themes from Proteolysis and Ubiquitin-conjugating enzyme. His Ubiquitin-conjugating enzyme research is multidisciplinary, incorporating elements of Biophysics, Ubiquitins, Substrate and Deubiquitination.
His Ubiquitin ligase study combines topics in areas such as Securin and CDC20. Randall W. King interconnects Autophagy, Mutant, Protein degradation and Cyclin B in the investigation of issues within Deubiquitinating enzyme. In general Cell biology study, his work on Mitosis often relates to the realm of Tauopathy, thereby connecting several areas of interest.
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Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen
Thomas U. Mayer;Tarun M. Kapoor;Stephen J. Haggarty;Randall W. King.
How proteolysis drives the cell cycle
Randall W. King;Raymond J. Deshaies;Jan-Michael Peters;Marc W. Kirschner.
A 20s complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
Randall W King;Jan-Michael Peters;Stuart Tugendreich;Mark Rolfe.
Enhancement of proteasome activity by a small-molecule inhibitor of USP14
Byung Hoon Lee;Min Jae Lee;Soyeon Park;Dong Chan Oh;Dong Chan Oh.
Mitosis in transition
Randall W. King;Peter K. Jackson;Marc W. Kirschner.
Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor
Sandra L. Holloway;Michael Glotzer;Randall W. King;Andrew W. Murray.
A Nonapoptotic Cell Death Process, Entosis, that Occurs by Cell-in-Cell Invasion
Michael Overholtzer;Arnaud A. Mailleux;Ghassan Mouneimne;Guillaume Normand.
Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines
Qinghua Shi;Randall W. King.
Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology
Donald S. Kirkpatrick;Nathaniel A. Hathaway;John Hanna;Suzanne Elsasser.
Nature Cell Biology (2006)
Deubiquitinating Enzyme Ubp6 Functions Noncatalytically to Delay Proteasomal Degradation
John Hanna;Nathaniel A. Hathaway;Yoshiko Tone;Bernat Crosas;Bernat Crosas.
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