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Ludger Klein-Hitpass

Ludger Klein-Hitpass

D-Index & Metrics

Genetics

D-Index
64
Citations
13896
World Ranking
2801
National Ranking
199

Overview

Ludger Klein-Hitpass is affiliated with the University of Duisburg-Essen in Germany. Their research spans multiple fields within biomedical science, focusing primarily on Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology.

Their work covers a range of subfields, including Immunology, Molecular Biology, Genetics, Oncology, and Pulmonary and Respiratory Medicine. The main research topics addressed by Ludger Klein-Hitpass involve Immune Response and Inflammation, Epigenetics and DNA Methylation, Identity, Memory, and Therapy, Chronic Lymphocytic Leukemia Research, Glioma Diagnosis and Treatment, Advanced Electron Microscopy Techniques and Applications, and Sarcoma Diagnosis and Treatment.

Frequent coauthors in their publications include Ulrich Dührsen, Patricia Johansson, Bettina Budeus, Jan Dürig, and Inken Wohlers. These collaborations appear consistently across their recent scientific contributions.

Notable recent papers authored or coauthored by Ludger Klein-Hitpass include:

  • CDKN2A deletion in supratentorial ependymoma with RELA alteration indicates a dismal prognosis: a retrospective analysis of the HIT ependymoma trial cohort (2020, Acta Neuropathologica)
  • Acute myeloid leukemia-induced remodeling of the human bone marrow niche predicts clinical outcome (2020, Blood Advances)
  • Targeted bisulfite sequencing: A novel tool for the assessment of DNA methylation with high sensitivity and increased coverage (2020, Psychoneuroendocrinology)
  • Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted Sequencing (2020, Cancers)
  • Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemia (2020, Therapeutic Advances in Hematology)

Their publications have appeared frequently in journals such as Frontiers in Immunology, Acta Neuropathologica, Blood Advances, Psychoneuroendocrinology, and Cancers, demonstrating interdisciplinary reach within clinical and molecular biomedical research.

Best Publications

  • An estrogen-responsive element derived from the 5' flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells.

    L Klein-Hitpass;M Schorpp;U Wagner;G U Ryffel

  • A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor

    Ludger Klein-Hitpass;Gerhart U. Ryffel;Ellen Heitlinger;Andrew C.B. Cato

  • Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3.

    Marcel Martin;Marcel Martin;Lars Maßhöfer;Petra Temming;Sven Rahmann

  • Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy

    Johannes H. Schulte;Soyoung Lim;Alexander Schramm;Nicolaus Friedrichs

  • LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression

    Jan J Molenaar;Raquel Domingo-Fernández;Marli E Ebus;Sven Lindner

  • Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells

    Hui Zeng;Raif Yücel;Christian Kosan;Ludger Klein‐Hitpass

  • ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia

    J Dürig;H Nückel;M Cremer;A Führer

  • MYCN regulates oncogenic MicroRNAs in neuroblastoma.

    Johannes H. Schulte;Sebastian Horn;Tobias Otto;Birgit Samans

  • The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element.

    Jurgen Behrens;Oliver Lowrick;Ludger Klein-Hitpass;Walter Birchmeier

  • Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemia.

    R Schroers;F Griesinger;L Trümper;D Haase

  • The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex.

    Ludger Klein-Hitpass;Sophia Y. Tsai;Nancy L. Weigel;George F. Allan

  • A comprehensive molecular study on Coffin-Siris and Nicolaides-Baraitser syndromes identifies a broad molecular and clinical spectrum converging on altered chromatin remodeling.

    Dagmar Wieczorek;Nina Bögershausen;Filippo Beleggia;Sabine Steiner-Haldenstätt

  • Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions.

    Antje Sucker;Fang Zhao;Natalia Pieper;Christina Heeke

  • The Transcriptional Profile of Mesenchymal Stem Cell Populations in Primary Osteoporosis Is Distinct and Shows Overexpression of Osteogenic Inhibitors

    Peggy Benisch;Tatjana Schilling;Ludger Klein-Hitpass;Sönke P. Frey

  • Two types of antiprogestins identified by their differential action in transcriptionally active extracts from T47D cells

    Ludger Klein-Hitpass;Andrew C.B. Cato;David Henderson;Gerhart U. Ryffel

  • Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degeneration

    Julia Kohler;Cvetan Popov;Barbara Klotz;Paolo Alberton

  • Protein Kinase C-β-Dependent Activation of NF-κB in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B Cells In Vivo

    Gloria Lutzny;Thomas Kocher;Marc Schmidt-Supprian;Martina Rudelius

  • Smoking and cancer-related gene expression in bronchial epithelium and non-small-cell lung cancers.

    M. Woenckhaus;L. Klein-Hitpass;U. Grepmeier;J. Merk

  • The Transcriptional Repressor Gfi1 Affects Development of Early, Uncommitted c-Kit+ T Cell Progenitors and CD4/CD8 Lineage Decision in the Thymus

    Raif Yücel;Holger Karsunky;Ludger Klein-Hitpass;Tarik Möröy

  • Connexin43 Interacts with NOV A POSSIBLE MECHANISM FOR NEGATIVE REGULATION OF CELL GROWTH IN CHORIOCARCINOMA CELLS

    Alexandra Gellhaus;Xuesen Dong;Sven Propson;Karen Maass

Frequent Co-Authors

Ulrich Dührsen
Ulrich Dührsen University of Duisburg-Essen
Gerhart U. Ryffel
Gerhart U. Ryffel University of Duisburg-Essen
Bernhard Horsthemke
Bernhard Horsthemke University of Duisburg-Essen
Ralf Küppers
Ralf Küppers University of Duisburg-Essen
Johannes H. Schulte
Johannes H. Schulte Charité - University Medicine Berlin
Tarik Möröy
Tarik Möröy University of Montreal
Reiner Siebert
Reiner Siebert University of Ulm
Benedikt Brors
Benedikt Brors German Cancer Research Center
Gerd Schmitz
Gerd Schmitz University of Regensburg
Philip Rosenstiel
Philip Rosenstiel Kiel University

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