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Kazuyasu Sakaguchi

Kazuyasu Sakaguchi

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
25917
World Ranking
8950
National Ranking
601

Overview

Kazuyasu Sakaguchi is affiliated with Hokkaido University in Japan and primarily conducts research in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans several subfields including Molecular Biology, Oncology, Neurology, Nutrition and Dietetics, and Biophysics.

The research topics covered in their publications include:

  • Cancer-related Molecular Pathways
  • Ubiquitin and proteasome pathways
  • Neuroblastoma Research and Treatments
  • Epigenetics and DNA Methylation
  • Trace Elements in Health
  • ATP Synthase and ATPases Research
  • Cell Image Analysis Techniques

Recent papers by Sakaguchi include the following:

  • Metal-dependent Ser/Thr protein phosphatase PPM family: Evolution, structures, diseases and inhibitors (2020), published in Pharmacology & Therapeutics
  • PPM1D Is a Therapeutic Target in Childhood Neural Tumors (2021), published in Cancers
  • Characterization of a C-Terminal SUMO-Interacting Motif Present in Select PIAS-Family Proteins (2020), published in Structure
  • Zinc controls PML nuclear body formation through regulation of a paralog specific auto-inhibition in SUMO1 (2022), published in Nucleic Acids Research
  • Bilayer Hydrogel Composed of Elastin-Mimetic Polypeptides as a Bio-Actuator with Bidirectional and Reversible Bending Behaviors (2023), published in Molecules

Their frequent co-authors include:

  • Rui Kamada
  • James G. Omichinski
  • Jose Isagani B. Janairo
  • Haytham M. Wahba
  • Itsumi Tani

Sakaguchi's publications often appear in the following venues:

  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biochemical and Biophysical Research Communications
  • Pharmacology & Therapeutics
  • Cancers

Best Publications

  • Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

    Christine E. Canman;Dae Sik Lim;Karlene A. Cimprich;Yoichi Taya

  • Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry

    Donald F. Hunt;Robert A. Henderson;Jeffrey Shabanowitz;Kazuyasu Sakaguchi

  • DNA damage activates p53 through a phosphorylation–acetylation cascade

    Kazuyasu Sakaguchi;Julio E. Herrera;Shin’ichi Saito;Toru Miki

  • Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection.

    Y Kawakami;S Eliyahu;C H Delgado;P F Robbins

  • Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes.

    Yutaka Kawakami;Siona Eliyahu;Kazuyasu Sakaguchi;Paul F. Robbins

  • DNA DAMAGE INDUCES PHOSPHORYLATION OF THE AMINO TERMINUS OF P53

    Janet D. Siliciano;Christine E. Canman;Yoichi Taya;Kazuyasu Sakaguchi

  • Phosphorylation of human p53 by p38 kinase coordinates N‐terminal phosphorylation and apoptosis in response to UV radiation

    Bulavin Dv;Saito S;Hollander Mc;Sakaguchi K;Sakaguchi K

  • Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad

    Donald F. Hunt;Hanspeter Michel;Tracey A. Dickinson;Jeffrey Shabanowitz

  • Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression.

    Y. Kawakami;S. Eliyahu;C. Jennings;K. Sakaguchi

  • HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation.

    Robert A. Henderson;Hanspeter Michel;Kazuyasu Sakaguchi;Jeffrey Shabanowitz

  • Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

    S P Lees-Miller;K Sakaguchi;S J Ullrich;E Appella

  • Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

    M Fiscella;H Zhang;S Fan;K Sakaguchi

  • Induction of tumor-reactive CTL from peripheral blood and tumor-infiltrating lymphocytes of melanoma patients by in vitro stimulation with an immunodominant peptide of the human melanoma antigen MART-1.

    Licia Rivoltini;Yutaka Kawakami;Kazuyasu Sakaguchi;Scott Southwood

  • High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

    GM Clore;JG Omichinski;K Sakaguchi;N Zambrano

  • Vasostatin, a Calreticulin Fragment, Inhibits Angiogenesis and Suppresses Tumor Growth

    Sandra E. Pike;Lei Yao;Karen D. Jones;Barry Cherney

  • Definition of specific peptide motifs for four major HLA-A alleles.

    R T Kubo;A Sette;H M Grey;E Appella

  • Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase. Effect on Mdm2 binding.

    Kazuyasu Sakaguchi;Shin'ichi Saito;Yuichiro Higashimoto;Siddhartha Roy

  • Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41.

    Isabel Muñoz-Barroso;Stewart Durell;Kazuyasu Sakaguchi;Ettore Appella

  • Phosphorylation of Serine 392 Stabilizes the Tetramer Formation of Tumor Suppressor Protein p53

    Kazuyasu Sakaguchi;Hiroshi Sakamoto;Marc S. Lewis;Carl W. Anderson

  • Refined solution structure of the oligomerization domain of the tumour suppressor p53.

    G M Clore;J Ernst;R Clubb;J G Omichinski

Frequent Co-Authors

Ettore Appella
Ettore Appella National Institutes of Health
Carl W. Anderson
Carl W. Anderson Brookhaven National Laboratory
Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
Kohei Uosaki
Kohei Uosaki National Institute for Materials Science
Angela M. Gronenborn
Angela M. Gronenborn University of Pittsburgh
Donald F. Hunt
Donald F. Hunt University of Virginia
Yutaka Kawakami
Yutaka Kawakami International University Of Health And Welfare Atami Hospital
Howard M. Grey
Howard M. Grey La Jolla Institute For Allergy & Immunology
Steven A. Rosenberg
Steven A. Rosenberg National Institutes of Health
Jeffrey Shabanowitz
Jeffrey Shabanowitz University of Virginia

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