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Biology and Biochemistry

D-Index
66
Citations
34068
World Ranking
8438
National Ranking
3797

Overview

Justin R. Cross is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research spans a multidisciplinary approach involving biochemistry, genetics, molecular biology, and medicine, with significant contributions across these fields.

The scientist's main fields of study include Biochemistry, Genetics and Molecular Biology with 96 publications, and Medicine with 77 publications. Their work focuses on several subfields including Molecular Biology, Immunology, Cancer Research, Oncology, and Hematology.

Primary topics covered in their research are:

  • Cancer, Hypoxia, and Metabolism
  • Gut microbiota and health
  • Immune Cell Function and Interaction
  • Mitochondrial Function and Pathology
  • RNA modifications and cancer
  • Metabolism and Genetic Disorders
  • Hematopoietic Stem Cell Transplantation

Some of the recent papers published by Justin R. Cross include:

  • Connecting copper and cancer: from transition metal signalling to metalloplasia, 2021, Nature reviews. Cancer
  • Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells, 2020, Nature
  • Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen, 2020, Nature Immunology
  • Microbiota modulate sympathetic neurons via a gut-brain circuit, 2020, Nature
  • Copper depletion modulates mitochondrial oxidative phosphorylation to impair triple negative breast cancer metastasis, 2021, Nature Communications

Frequent co-authors of this scientist include:

  • Jonathan U. Peled
  • Sara Violante
  • Marcel R.M. van den Brink
  • Sergio Giralt
  • Peter Adintori

Justin R. Cross has published extensively in several key venues, with multiple publications in:

  • Blood (15 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (14 publications)
  • Nature (6 publications)
  • Cancer Research (4 publications)
  • Cell Reports (3 publications)

The scientist has also contributed to book publications, notably:

  • In Celebration of Women in Molecular and Cellular Reproduction, 2024, Frontiers Media

Best Publications

  • Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

    Nicholas Arpaia;Clarissa Campbell;Xiying Fan;Stanislav Dikiy

  • The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

    Patrick S. Ward;Jay Patel;David R. Wise;Omar Abdel-Wahab

  • ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

    Kathryn E. Wellen;Georgia Hatzivassiliou;Uma M. Sachdeva;Thi V. Bui

  • Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.

    Charlie G. Buffie;Vanni Bucci;Vanni Bucci;Richard R. Stein;Peter T. McKenney

  • Toll-like Receptor-Induced Changes in Glycolytic Metabolism Regulate Dendritic Cell Activation

    Connie M. Krawczyk;Connie M. Krawczyk;Thomas Holowka;Jie Sun;Julianna Blagih

  • Connecting copper and cancer: from transition metal signalling to metalloplasia.

    Eva J Ge;Ashley I Bush;Angela Casini;Paul A Cobine

  • Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability

    David R. Wise;Patrick S. Ward;Jessica E. S. Shay;Justin R. Cross

  • Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells

    Bryce W. Carey;Lydia W. S. Finley;Justin R. Cross;C. David Allis

  • Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia.

    Bianca D. Santomasso;Jae H. Park;Darin Salloum;Isabelle Riviere

  • Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer

    Qing Chen;Adrienne Boire;Xin Jin;Manuel Valiente

  • Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease

    Robert R. Jenq;Robert R. Jenq;Ying Taur;Ying Taur;Sean M. Devlin;Doris M. Ponce;Doris M. Ponce

  • Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids

    Jurre J. Kamphorst;Justin R. Cross;Jing Fan;Elisa de Stanchina

  • Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells

    Clarissa Campbell;Peter T. McKenney;Peter T. McKenney;Daniel Konstantinovsky;Olga I. Isaeva

  • Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation

    Benjamin R. Sabari;Zhanyun Tang;He Huang;Vladimir Yong-Gonzalez

  • Hypoxia Induces Production of L-2-Hydroxyglutarate

    Andrew M. Intlekofer;Raymond G. Dematteo;Sriram Venneti;Lydia W.S. Finley

  • Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen.

    Santosha A. Vardhana;Madeline A. Hwee;Mirela Berisa;Daniel K. Wells

  • Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia

    Jiangbin Ye;Jing Fan;Sriram Venneti;Ying Wooi Wan

  • Commensal bacteria make GPCR ligands that mimic human signalling molecules

    Louis J. Cohen;Louis J. Cohen;Daria Esterhazy;Seong-Hwan Kim;Christophe Lemetre

  • Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion

    Ji Zhang;Jing Fan;Sriram Venneti;Justin R. Cross

  • The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis.

    Eve-Ellen Govek;Eve-Ellen Govek;Sarah E Newey;Colin J Akerman;Justin R Cross

Frequent Co-Authors

Craig B. Thompson
Craig B. Thompson Memorial Sloan Kettering Cancer Center
Marcel R.M. van den Brink
Marcel R.M. van den Brink Memorial Sloan Kettering Cancer Center
Eric G. Pamer
Eric G. Pamer Memorial Sloan Kettering Cancer Center
Ying Taur
Ying Taur Memorial Sloan Kettering Cancer Center
Sergio Giralt
Sergio Giralt Memorial Sloan Kettering Cancer Center
Chao Lu
Chao Lu Hong Kong Polytechnic University
Miguel-Angel Perales
Miguel-Angel Perales Memorial Sloan Kettering Cancer Center
Robert R. Jenq
Robert R. Jenq The University of Texas MD Anderson Cancer Center
Lisa M. DeAngelis
Lisa M. DeAngelis Memorial Sloan Kettering Cancer Center
Scott W. Lowe
Scott W. Lowe Memorial Sloan Kettering Cancer Center

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