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Biology and Biochemistry

D-Index
62
Citations
28988
World Ranking
10513
National Ranking
4561

Overview

Robert R. Jenq is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research spans medicine and biochemistry, genetics, and molecular biology, with a focus on several interrelated subfields. These include molecular biology, oncology, hematology, epidemiology, and immunology.

The primary topics of Jenq's work reflect a strong interest in the interaction between the microbiome and cancer, as well as hematopoietic stem cell transplantation and immune-related treatments. Main research topics include:

  • Gut microbiota and health
  • Hematopoietic Stem Cell Transplantation
  • Neutropenia and Cancer Infections
  • Clostridium difficile and Clostridium perfringens research
  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • Probiotics and Fermented Foods

Jenq has contributed to multiple recent papers that are noted for their publication in high-impact journals and significant citation numbers. Selected recent publications include:

  • "Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response," 2021, Science
  • "Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation," 2020, New England Journal of Medicine
  • "Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial," 2021, Nature Medicine
  • "Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade," 2021, Nature Medicine
  • "Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer," 2022, Cancer Cell

Research collaborations are a notable aspect of Jenq's scientific output. Frequent co-authors include Christine B. Peterson, Nadim J. Ajami, Chia-Chi Chang, Liangliang Zhang, and Jennifer A. Wargo.

Jenq's contributions have appeared predominantly in journals specializing in hematology, cancer research, and immunology. The most frequent publication venues are Blood, bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Nature Medicine, and Transplantation and Cellular Therapy.

Best Publications

  • Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

    V. Gopalakrishnan;V. Gopalakrishnan;C. N. Spencer;C. N. Spencer;L. Nezi;A. Reuben

  • Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.

    Charlie G. Buffie;Vanni Bucci;Vanni Bucci;Richard R. Stein;Peter T. McKenney

  • Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes

    Erick Riquelme;Erick Riquelme;Yu Zhang;Liangliang Zhang;Maria Montiel

  • Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

    Caroline A. Lindemans;Caroline A. Lindemans;Marco Calafiore;Anna M. Mertelsmann;Margaret H. O'Connor

  • Intestinal Domination and the Risk of Bacteremia in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

    Ying Taur;Joao B. Xavier;Lauren Lipuma;Carles Ubeda

  • Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans

    Carles Ubeda;Ying Taur;Robert R. Jenq;Michele J. Equinda

  • The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation.

    Ying Taur;Ying Taur;Robert R Jenq;Robert R Jenq;Miguel Angel Perales;Miguel Angel Perales;Eric R. Littmann

  • Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease

    Robert R. Jenq;Robert R. Jenq;Ying Taur;Ying Taur;Sean M. Devlin;Doris M. Ponce;Doris M. Ponce

  • Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease.

    Nathan D. Mathewson;Robert R Jenq;Anna V. Mathew;Mark Koenigsknecht

  • Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

    Yinghong Wang;Diana H. Wiesnoski;Beth A. Helmink;Vancheswaran Gopalakrishnan

  • Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation

    Jonathan U Peled;Antonio L C Gomes;Sean M Devlin;Eric R Littmann

  • Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation

    Robert R. Jenq;Robert R. Jenq;Carles Ubeda;Carles Ubeda;Ying Taur;Ying Taur;Clarissa C. Menezes

  • Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease.

    Alan M. Hanash;Jarrod A. Dudakov;Guoqiang Hua;Margaret H. O’Connor

  • Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice

    Yusuke Shono;Melissa D. Docampo;Jonathan U. Peled;Jonathan U. Peled;Suelen M. Perobelli

  • Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial.

    Tina Cascone;William N. William;Annikka Weissferdt;Cheuk H. Leung

  • Intestinal Microbiota Containing Barnesiella Species Cures Vancomycin-Resistant Enterococcus faecium Colonization

    Carles Ubeda;Carles Ubeda;Vanni Bucci;Silvia Caballero;Silvia Caballero;Ana Djukovic

  • Interleukin-22 drives endogenous thymic regeneration in mice

    Jarrod A. Dudakov;Jarrod A. Dudakov;Alan M. Hanash;Robert R. Jenq;Robert R. Jenq;Lauren F. Young

  • Allogeneic haematopoietic stem cell transplantation: individualized stem cell and immune therapy of cancer

    Robert R. Jenq;Marcel R. M. van den Brink

  • Reconstitution of the gut microbiota of antibiotic-treated patients by autologous fecal microbiota transplant

    Ying Taur;Katharine Coyte;Katharine Coyte;Katharine Coyte;Jonas Schluter;Elizabeth Robilotti

  • Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation

    Jonathan U. Peled;Sean M. Devlin;Anna Staffas;Melissa Lumish

Frequent Co-Authors

Marcel R.M. van den Brink
Marcel R.M. van den Brink Memorial Sloan Kettering Cancer Center
Eric G. Pamer
Eric G. Pamer Memorial Sloan Kettering Cancer Center
Ying Taur
Ying Taur Memorial Sloan Kettering Cancer Center
Sergio Giralt
Sergio Giralt Memorial Sloan Kettering Cancer Center
Miguel-Angel Perales
Miguel-Angel Perales Memorial Sloan Kettering Cancer Center
Chen Liu
Chen Liu Yale University
George F. Murphy
George F. Murphy Brigham and Women's Hospital
Kim Anh Do
Kim Anh Do The University of Texas MD Anderson Cancer Center
Jennifer A. Wargo
Jennifer A. Wargo The University of Texas MD Anderson Cancer Center
Ernst Holler
Ernst Holler University of Regensburg

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