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Alexander Hüttenhofer

Alexander Hüttenhofer

D-Index & Metrics

Molecular Biology

D-Index
49
Citations
10635
World Ranking
2618
National Ranking
14

Overview

Alexander Hüttenhofer is a researcher affiliated with Innsbruck Medical University in Austria. Their work primarily spans the fields of biochemistry, genetics, and molecular biology, with a particular focus on molecular biology and cancer research as key subfields.

The scientist's research topics include:

  • MicroRNA in disease regulation
  • RNA research and splicing
  • Cancer-related molecular mechanisms research
  • CRISPR and genetic engineering
  • RNA regulation and disease
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms

Alexander Hüttenhofer has published across several scientific venues, with frequent appearances in:

  • Molecular Cell
  • Cells
  • Molecular Therapy - Nucleic Acids
  • Nature Structural & Molecular Biology

Notable recent publications include:

  • "SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts" (2020, Molecular Cell)
  • "Intragenic MicroRNAs Autoregulate Their Host Genes in Both Direct and Indirect Ways-A Cross-Species Analysis" (2020, Cells)
  • "Differentially expressed ncRNAs as key regulators in infection of human bronchial epithelial cells by the SARS-CoV-2 Delta variant" (2025, Molecular Therapy - Nucleic Acids)
  • "tRNA as an assembly chaperone for a macromolecular transcription-processing complex" (2025, Nature Structural & Molecular Biology)

Throughout their career, Hüttenhofer has collaborated with several frequent co-authors, including:

  • Kai K. Kummer
  • Katharina Hutter
  • Michael Lohmüller
  • Almina Jukic
  • Felix Eichin

Best Publications

  • Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization.

    Jérôme Cavaillé;Karin Buiting;Martin Kiefmann;Marc Lalande

  • Non-coding RNAs: hope or hype?

    Alexander Hüttenhofer;Peter Schattner;Norbert Polacek

  • RNomics in Escherichia coli detects new sRNA species and indicates parallel transcriptional output in bacteria

    Jörg Vogel;Verena Bartels;Thean Hock Tang;Gennady Churakov

  • The IC-SNURF–SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A

    Maren Runte;Alexander Hüttenhofer;Stephanie Groß;Martin Kiefmann

  • Mapping of conserved RNA secondary structures predicts thousands of functional noncoding RNAs in the human genome

    Stefan Washietl;Ivo L Hofacker;Melanie Lukasser;Alexander Hüttenhofer

  • Identification of 86 candidates for small non-messenger RNAs from the archaeon Archaeoglobus fulgidus

    Thean-Hock Tang;Jean-Pierre Bachellerie;Timofey Rozhdestvensky;Marie-Line Bortolin

  • RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse

    Alexander Hüttenhofer;Martin Kiefmann;Sebastian Meier‐Ewert;Sebastian Meier‐Ewert;John O'Brien;John O'Brien

  • ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs

    Patrice Vitali;Patrice Vitali;Eugenia Basyuk;Elodie Le Meur;Edouard Bertrand

  • Identification of novel non-coding RNAs as potential antisense regulators in the archaeon Sulfolobus solfataricus

    Thean-Hock Tang;Norbert Polacek;Marek Zywicki;Marek Zywicki;Harald Huber

  • Binding of L7Ae protein to the K-turn of archaeal snoRNAs: a shared RNA binding motif for C/D and H/ACA box snoRNAs in Archaea

    Timofey S. Rozhdestvensky;Thean Hock Tang;Inna V. Tchirkova;Jürgen Brosius

  • Experimental approaches to identify non-coding RNAs

    Alexander Hüttenhofer;Jörg Vogel

  • Small ncRNA transcriptome analysis from Aspergillus fumigatus suggests a novel mechanism for regulation of protein synthesis

    Christoph Jöchl;Mathieu Rederstorff;Jana Hertel;Peter F. Stadler

  • The small RNA PhrS stimulates synthesis of the Pseudomonas aeruginosa quinolone signal

    Elisabeth Sonnleitner;Nicolas Gonzalez;Theresa Sorger-Domenigg;Stephan Heeb

  • Experimental RNomics: identification of 140 candidates for small non-messenger RNAs in the plant Arabidopsis thaliana.

    Claudia Marker;Anja Zemann;Tanja Terhörst;Martin Kiefmann

  • Poly(A)-binding protein is associated with neuronal BC1 and BC200 ribonucleoprotein particles.

    Ravi Sondekoppa Muddashetty;Tasneem Khanam;Alexander Kondrashov;Marsha Bundman

  • RNomics: identification and function of small, non-messenger RNAs.

    Alexander Hüttenhofer;Jürgen Brosius;Jean Pierre Bachellerie

  • Identification of small non-coding RNAs from mitochondria and chloroplasts

    Birgit Lung;Anja Zemann;Monika J. Madej;Markus Schuelke

  • RNomics in Archaea reveals a further link between splicing of archaeal introns and rRNA processing

    Thean Hock Tang;Timofey S. Rozhdestvensky;Béatrice Clouet d’Orval;Marie-Line Bortolin

  • Anopheles gambiae miRNAs as actors of defence reaction against Plasmodium invasion

    Flore Winter;Sonia Edaye;Alexander Hüttenhofer;Christine Brunel

  • Nucleotide modifications within bacterial messenger RNAs regulate their translation and are able to rewire the genetic code

    Thomas Philipp Hoernes;Nina Clementi;Klaus Faserl;Heidelinde Glasner

Frequent Co-Authors

Peter F. Stadler
Peter F. Stadler Leipzig University
Herbert Lindner
Herbert Lindner Innsbruck Medical University
Ivo L. Hofacker
Ivo L. Hofacker University of Vienna
Florian Kronenberg
Florian Kronenberg Innsbruck Medical University
Timothy W. Bredy
Timothy W. Bredy University of Queensland
Udo Bläsi
Udo Bläsi University of Vienna
Hubertus Haas
Hubertus Haas Innsbruck Medical University
Lukas A. Huber
Lukas A. Huber Innsbruck Medical University
Alexander S. Mankin
Alexander S. Mankin University of Illinois at Chicago
Nicolas Singewald
Nicolas Singewald University of Innsbruck

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