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Biology and Biochemistry

D-Index
55
Citations
14075
World Ranking
14859
National Ranking
165

Overview

Jan Gorodkin is affiliated with the University of Copenhagen in Denmark. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Genetics, Biomedical Engineering, Cancer Research, and Biotechnology.

Their work covers several main topics, including:

  • RNA and protein synthesis mechanisms
  • CRISPR and Genetic Engineering
  • RNA modifications and cancer
  • Advanced biosensing and bioanalysis techniques
  • Inflammatory Bowel Disease
  • Cancer-related molecular mechanisms research
  • RNA Research and Splicing

Recent publications by Jan Gorodkin include:

  • "RNAcentral 2021: secondary structure integration, improved sequence search and new member databases," 2020, Nucleic Acids Research
  • "Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning," 2021, Nature Communications
  • "Good guide, bad guide: spacer sequence-dependent cleavage efficiency of Cas12a," 2020, Nucleic Acids Research
  • "CRISPR/Cas9 gRNA activity depends on free energy changes and on the target PAM context," 2022, Nature Communications
  • "Human pathways in animal models: possibilities and limitations," 2021, Nucleic Acids Research

Frequent co-authors collaborating with Jan Gorodkin are:

  • Christian Anthon
  • Stefan E. Seemann
  • Giulia I. Corsi
  • Nadezhda T. Doncheva
  • Adrian Sven Geissler

Their work has appeared predominantly in the following publication venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nucleic Acids Research
  • Frontiers in Immunology
  • Bioinformatics

Best Publications

  • Human polymorphism at microRNAs and microRNA target sites.

    Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang

  • Cytoscape StringApp: Network Analysis and Visualization of Proteomics Data.

    Nadezhda T. Doncheva;John H. Morris;Jan Gorodkin;Lars J. Jensen

  • Analyses of pig genomes provide insight into porcine demography and evolution

    Martien A. M. Groenen;Alan L. Archibald;Hirohide Uenishi;Christopher K. Tuggle

  • Comparing two K-category assignments by a K-category correlation coefficient

    J. Gorodkin

  • Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing.

    Rasmus Wernersson;Mikkel H Schierup;Frank G Jørgensen;Jan Gorodkin

  • RNAcentral 2021: secondary structure integration, improved sequence search and new member databases

    Blake A Sweeney;Anton I Petrov;Carlos E Ribas

  • RNAcentral: a hub of information for non-coding RNA sequences

    Blake A Sweeney;Anton I Petrov;Boris Burkov

  • Finding the most significant common sequence and structure motifs in a set of RNA sequences

    Jan Gorodkin;L.J. Heyer;G.D. Stormo

  • Displaying the information contents of structural RNA alignments: the structure logos.

    Jan Gorodkin;Laurie J. Heyer;Søren Brunak;Gary D. Stormo

  • Pairwise local structural alignment of RNA sequences with sequence similarity less than 40

    Jakob Hull Havgaard;Rune B. Lyngsø;Gary D. Stormo;Jan Gorodkin

  • Protein-driven inference of miRNA–disease associations

    Søren Mørk;Sune Pletscher-Frankild;Albert Palleja Caro;Jan Gorodkin

  • Thousands of corresponding human and mouse genomic regions unalignable in primary sequence contain common RNA structure

    Elfar Torarinsson;Milena Sawera;Jakob H. Havgaard;Merete Fredholm

  • Discovering common stem-loop motifs in unaligned RNA sequences

    Jan Gorodkin;Shawn L. Stricklin;Gary D. Stormo

  • Protein distance constraints predicted by neural networks and probability density functions.

    O Lund;K Frimand;J Gorodkin;H Bohr

  • Multiple structural alignment and clustering of RNA sequences

    Elfar Torarinsson;Jakob H. Havgaard;Jan Gorodkin

  • Profiling of Ribose Methylations in RNA by High‐Throughput Sequencing

    Ulf Birkedal;Mikkel Christensen-Dalsgaard;Nicolai Krogh;Radhakrishnan Sabarinathan

  • Transcriptomic landscape of lncRNAs in inflammatory bowel disease

    Aashiq H Mirza;Claus Hb Berthelsen;Stefan E Seemann;Xiaoyong Pan

  • SRPDB (Signal Recognition Particle Database)

    Jan Gorodkin;Bjarne Knudsen;Christian W Zwieb;Tore Samuelsson

  • TISSUES 2.0: an integrative web resource on mammalian tissue expression

    Oana Palasca;Alberto Santos;Christian Stolte;Jan Gorodkin

  • RNAsnp: Efficient Detection of Local RNA Secondary Structure Changes Induced by SNPs

    Radhakrishnan Sabarinathan;Hakim Tafer;Stefan E. Seemann;Ivo L. Hofacker;Ivo L. Hofacker

Frequent Co-Authors

Peter F. Stadler
Peter F. Stadler Leipzig University
Ivo L. Hofacker
Ivo L. Hofacker University of Vienna
Merete Fredholm
Merete Fredholm University of Copenhagen
Walter L. Ruzzo
Walter L. Ruzzo University of Washington
Rolf Backofen
Rolf Backofen University of Freiburg
Søren Brunak
Søren Brunak University of Copenhagen
Flemming Pociot
Flemming Pociot Steno Diabetes Center
Poul Hyttel
Poul Hyttel University of Copenhagen
Niels Tommerup
Niels Tommerup University of Copenhagen
Lars Bolund
Lars Bolund Aarhus University

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