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Biology and Biochemistry

D-Index
54
Citations
11499
World Ranking
15551
National Ranking
426

Overview

Mark D. Hulett is affiliated with La Trobe University in Australia and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology. Their work spans several subfields including Molecular Biology, Immunology, Cell Biology, Microbiology, and Plant Science.

The major research topics covered by Mark D. Hulett include:

  • Proteoglycans and glycosaminoglycans research
  • Antimicrobial Peptides and Activities
  • Glycosylation and Glycoproteins Research
  • Biochemical and Structural Characterization
  • Cell Adhesion Molecules Research
  • Fibroblast Growth Factor Research
  • Neuroinflammation and Neurodegeneration Mechanisms

Frequent collaborators in their research include:

  • Ivan K. H. Poon
  • Thanh Kha Phan
  • Tien K. Nguyen
  • Alyce J. Mayfosh
  • Amy A. Baxter

Mark D. Hulett's publications are regularly found in scientific venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biomolecules
  • Nature Communications
  • Small
  • International Journal of Molecular Sciences

Notable recent papers include:

  • "Heparanase and the hallmarks of cancer," 2020, Journal of Translational Medicine
  • "Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in COVID-19," 2022, Nature Communications
  • "TREML4 receptor regulates inflammation and innate immune cell death during polymicrobial sepsis," 2020, Nature Immunology
  • "The Heparanase Regulatory Network in Health and Disease," 2021, International Journal of Molecular Sciences
  • "An Ultrasound-Responsive Theranostic Cyclodextrin-Loaded Nanoparticle for Multimodal Imaging and Therapy for Atherosclerosis," 2022, Small

Best Publications

  • Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis.

    Mark D. Hulett;Craig Freeman;Brenton J. Hamdorf;Rohan T. Baker

  • Heparanase: a key enzyme involved in cell invasion.

    Christopher R. Parish;Craig Freeman;Mark D. Hulett

  • Molecular basis of Fc receptor function.

    Mark D. Hulett;P. Mark Hogarth

  • Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma

    Hina Kalra;Christopher G. Adda;Michael Liem;Ching-Seng Ang

  • Molecular mechanisms of late apoptotic/necrotic cell clearance.

    Ivan Ka Ho. Poon;Ivan Ka Ho. Poon;Mark Darren. Hulett;Mark Darren. Hulett;Christopher R. Parish

  • Histidine-rich glycoprotein: A novel adaptor protein in plasma that modulates the immune, vascular and coagulation systems.

    Allison L Jones;Mark D Hulett;Christopher R Parish

  • A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure

    Georgia K. Atkin-Smith;Rochelle Tixeira;Stephanie Paone;Suresh Mathivanan

  • Immunotherapy of Cytotoxic T Cell–resistant Tumors by T Helper 2 Cells An Eotaxin and STAT6-dependent Process

    Joerg Mattes;Mark Hulett;Wei Xie;Simon Hogan

  • HYBRID Fc RECEPTOR MOLECULES

    Phillip Mark Hogarth;Mark Darren Hulett;Francesco Libero Ierino;Ian Farquhar Campbell Mckenzie

  • Crystal structure of the human leukocyte Fc receptor, Fc gammaRIIa.

    K. F. Maxwell;M. S. Powell;M. D. Hulett;P. A. Barton

  • Histidine-rich glycoprotein: the Swiss Army knife of mammalian plasma

    Ivan K. H. Poon;Ivan K. H. Poon;Kruti K. Patel;David S. Davis;Christopher R. Parish

  • Soluble heparan sulfate fragments generated by heparanase trigger the release of pro-inflammatory cytokines through TLR-4.

    Katharine J. Goodall;Ivan K. H. Poon;Simon Phipps;Mark D. Hulett

  • Endothelial cell apoptosis and the role of endothelial cell-derived extracellular vesicles in the progression of atherosclerosis.

    Stephanie Paone;Amy A Baxter;Mark D Hulett;Ivan K H Poon

  • Identification of active site residues of the pro-metastatic endoglycosidase heparanase

    Mark D. Hulett;June R. Hornby;Stephen J. Ohms;Johannes Zuegg

  • Phosphoinositide-mediated oligomerization of a defensin induces cell lysis.

    Ivan K H Poon;Amy A. Baxter;Fung T. Lay;Grant D. Mills

  • Convergent evolution of defensin sequence, structure and function

    Thomas M. A. Shafee;Fung T. Lay;Thanh Kha Phan;Marilyn A. Anderson

  • The defensins consist of two independent, convergent protein superfamilies

    Thomas M. A. Shafee;Fung T. Lay;Mark D. Hulett;Marilyn A. Anderson

  • Identification of residues in the first domain of human Fc alpha receptor essential for interaction with IgA.

    Bruce D. Wines;Mark D. Hulett;Gary P. Jamieson;Halina M. Trist

  • Moving beyond size and phosphatidylserine exposure: evidence for a diversity of apoptotic cell-derived extracellular vesicles in vitro

    Ivan K. H. Poon;Michael A. F. Parkes;Lanzhou Jiang;Georgia K. Atkin-Smith

  • The MS4A family: counting past 1, 2 and 3.

    Li Eon Kuek;Melanie Leffler;Graham A Mackay;Mark D Hulett

Frequent Co-Authors

Christopher R. Parish
Christopher R. Parish Australian National University
Marilyn A. Anderson
Marilyn A. Anderson La Trobe University
P. Mark Hogarth
P. Mark Hogarth Burnet Institute
Ian F. C. McKenzie
Ian F. C. McKenzie University of Melbourne
Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Suresh Mathivanan
Suresh Mathivanan La Trobe University
Levon M. Khachigian
Levon M. Khachigian University of New South Wales
Klaus I. Matthaei
Klaus I. Matthaei Australian National University
Weisan Chen
Weisan Chen La Trobe University
Marco J. Herold
Marco J. Herold Walter and Eliza Hall Institute of Medical Research

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