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D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
19103
World Ranking
5088
National Ranking
122

Research.com Recognitions

  • 2003 - Gottschalk Medal, Australian Academy of Science

Overview

Levon M. Khachigian is affiliated with the University of New South Wales in Australia. Their research spans fields including Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on subfields such as Molecular Biology, Oncology, Immunology, Physiology, and Pathology and Forensic Medicine.

The scientist's main topics of research include:

  • Angiogenesis and VEGF in Cancer
  • CAR-T cell therapy research
  • Cancer-related molecular mechanisms research
  • Cardiac Ischemia and Reperfusion
  • RNA Research and Splicing
  • Peptidase Inhibition and Analysis
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Recent publications by Levon M. Khachigian include:

  • Emerging therapeutic strategies for unmet need in neovascular age-related macular degeneration, 2023, Journal of Translational Medicine
  • Early Growth Response-1, an Integrative Sensor in Cardiovascular and Inflammatory Disease, 2021, Journal of the American Heart Association
  • Neutralizing the pathological effects of extracellular histones with small polyanions, 2020, Nature Communications

Frequent co-authors in their publications are:

  • Yue Li
  • Connor H. O'Meara
  • Zuhayr Jafri
  • Muntasir Billah
  • Ravinay Bhindi

Their work has been published significantly in journals such as:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • International Journal of Molecular Sciences
  • Journal of Translational Medicine
  • Vascular Pharmacology
  • Journal of the American Heart Association

Levon M. Khachigian was awarded the Gottschalk Medal by the Australian Academy of Science in 2003.

Best Publications

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

    Erik Arner;Carsten O. Daub;Kristoffer Vitting-Seerup;Robin Andersson

  • Egr-1-Induced Endothelial Gene Expression: A Common Theme in Vascular Injury

    Levon M. Khachigian;Volkhard Lindner;Amy J. Williams;Tucker Collins

  • Coronary in-stent restenosis: Current status and future strategies

    Harry C Lowe;Stephen N Oesterle;Levon M Khachigian

  • Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress.

    Levon M. Khachigian;Nitzan Resnick;Michael A. Gimbrone;Tucker Collins

  • Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth

    Roger G Fahmy;Crispin R Dass;Lun-Quan Sun;Colin N Chesterman

  • Sp1 Phosphorylation and Its Regulation of Gene Transcription

    Nicole Y. Tan;Levon M. Khachigian

  • Interplay of Sp1 and Egr-1 in the Proximal Platelet-derived Growth Factor A-Chain Promoter in Cultured Vascular Endothelial Cells

    Levon M. Khachigian;Amy J. Williams;Tucker Collins

  • New DNA enzyme targeting Egr-1 mRNA inhibits vascular smooth muscle proliferation and regrowth after injury

    Fernando S. Santiago;Harry C. Lowe;Mary M. Kavurma;Colin N. Chesterman

  • Early Growth Response-1 in Cardiovascular Pathobiology

    Levon M. Khachigian

  • FANTOM5 CAGE profiles of human and mouse samples

    Shuhei Noguchi;Takahiro Arakawa;Shiro Fukuda;Masaaki Furuno

  • DNAzyme targeting c-jun suppresses skin cancer growth

    Hong Cai;Fernando S. Santiago;Leonel Prado-Lourenco;Bo Wang;Bo Wang

  • Egr-1 is Activated in Endothelial Cells Exposed to Fluid Shear Stress and Interacts With a Novel Shear-Stress-Response Element in the PDGF A-Chain Promoter

    Levon M. Khachigian;Keith R. Anderson;Nancy J. Halnon;Michael A. Gimbrone

  • Collagen antibody-induced arthritis

    Levon M Khachigian

  • Galectin-1 interacts with the {alpha}5{beta}1 fibronectin receptor to restrict carcinoma cell growth via induction of p21 and p27.

    Christian Fischer;Hugo Sanchez-Ruderisch;Martina Welzel;Bertram Wiedenmann

  • Dominantly Inherited Constitutional Epigenetic Silencing of MLH1 in a Cancer-Affected Family Is Linked to a Single Nucleotide Variant within the 5'UTR

    Megan P. Hitchins;Robert W. Rapkins;Chau-To Kwok;Sameer Srivastava

  • Signaling and transcriptional control of Fas ligand gene expression

    M M Kavurma;L M Khachigian

  • Inducible Expression of Egr-1–Dependent Genes: A Paradigm of Transcriptional Activation in Vascular Endothelium

    Levon M. Khachigian;Tucker Collins

  • Effect of Deoxyribozymes Targeting c-Jun on Solid Tumor Growth and Angiogenesis in Rodents

    Guishui Zhang;Crispin R. Dass;Eric Sumithran;Nick Di Girolamo

  • Sp1 is a component of the cytokine-inducible enhancer in the promoter of vascular cell adhesion molecule-1.

    Andrew S. Neish;Levon M. Khachigian;Adam Park;Vijay R. Baichwal

Frequent Co-Authors

Colin N. Chesterman
Colin N. Chesterman University of New South Wales
Tucker Collins
Tucker Collins Boston Children's Hospital
Christopher R. Parish
Christopher R. Parish Australian National University
Timo Lassmann
Timo Lassmann Telethon Kids Institute
Alistair R. R. Forrest
Alistair R. R. Forrest Harry Perkins Institute of Medical Research
Frank Brombacher
Frank Brombacher University of Cape Town

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