2003 - Gottschalk Medal, Australian Academy of Science
His primary scientific interests are in Cell biology, Transcription factor, Gene expression, Promoter and Molecular biology. He has researched Cell biology in several fields, including Vascular smooth muscle, Internal medicine, Endothelium, Platelet-derived growth factor and Response element. His research in Transcription factor intersects with topics in Regulation of gene expression, Transcription and In vivo.
As part of the same scientific family, Levon M. Khachigian usually focuses on Gene expression, concentrating on Growth factor and intersecting with TATA box. His Promoter research is multidisciplinary, incorporating perspectives in Cellular differentiation and DNA-binding protein. His Molecular biology research incorporates themes from Vascular endothelial growth factor A, Gene, Zinc finger and Transactivation.
Cell biology, Molecular biology, Transcription factor, Internal medicine and Cancer research are his primary areas of study. Levon M. Khachigian interconnects Gene expression, Cell growth, Vascular smooth muscle, Growth factor and Fibroblast growth factor in the investigation of issues within Cell biology. His Molecular biology research integrates issues from Zinc finger, Platelet-derived growth factor, Platelet-derived growth factor receptor, Messenger RNA and Transcription.
His Transcription factor research includes elements of Promoter and Regulation of gene expression. His work carried out in the field of Internal medicine brings together such families of science as Endocrinology and Cardiology. His Cancer research study which covers Dz13 that intersects with Pathology.
Levon M. Khachigian focuses on Internal medicine, Cancer research, Cell biology, Transcription factor and Cardiology. Levon M. Khachigian combines subjects such as Oncology and Pathology with his study of Internal medicine. The various areas that Levon M. Khachigian examines in his Cancer research study include Inflammation, c-jun and Vascular permeability.
His studies in Cell biology integrate themes in fields like Endothelial stem cell, Gene expression, Vascular smooth muscle, Chromatin and Endothelium. Within one scientific family, Levon M. Khachigian focuses on topics pertaining to Promoter under Transcription factor, and may sometimes address concerns connected to Transcription. Levon M. Khachigian works mostly in the field of Transcription, limiting it down to topics relating to Regulation of gene expression and, in certain cases, Molecular biology and Computational biology, as a part of the same area of interest.
Levon M. Khachigian focuses on Regulation of gene expression, Internal medicine, microRNA, Cancer research and Transcription factor. His work deals with themes such as Promoter, Cap analysis gene expression and Molecular biology, which intersect with Regulation of gene expression. His study in Promoter is interdisciplinary in nature, drawing from both Enhancer and Transcription.
Review article, Clinical efficacy and Kidney is closely connected to Cardiology in his research, which is encompassed under the umbrella topic of Internal medicine. His Cancer research study combines topics from a wide range of disciplines, such as Zinc finger transcription factor, Inflammation, Interferon and VE-cadherin. As part of his studies on Transcription factor, he often connects relevant subjects like Cell biology.
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A promoter-level mammalian expression atlas
Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie.
Nature (2014)
Egr-1-Induced Endothelial Gene Expression: A Common Theme in Vascular Injury
Levon M. Khachigian;Volkhard Lindner;Amy J. Williams;Tucker Collins.
Science (1996)
Coronary in-stent restenosis: Current status and future strategies
Harry C Lowe;Stephen N Oesterle;Levon M Khachigian.
Journal of the American College of Cardiology (2002)
Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress.
Levon M. Khachigian;Nitzan Resnick;Michael A. Gimbrone;Tucker Collins.
Journal of Clinical Investigation (1995)
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
Erik Arner;Carsten O. Daub;Kristoffer Vitting-Seerup;Robin Andersson.
Science (2015)
DNAzyme targeting c-jun suppresses skin cancer growth
Hong Cai;Fernando S. Santiago;Leonel Prado-Lourenco;Bo Wang;Bo Wang.
Science Translational Medicine (2012)
Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth
Roger G Fahmy;Crispin R Dass;Lun-Quan Sun;Colin N Chesterman.
Nature Medicine (2003)
New DNA enzyme targeting Egr-1 mRNA inhibits vascular smooth muscle proliferation and regrowth after injury
Fernando S. Santiago;Harry C. Lowe;Mary M. Kavurma;Colin N. Chesterman.
Nature Medicine (1999)
Interplay of Sp1 and Egr-1 in the Proximal Platelet-derived Growth Factor A-Chain Promoter in Cultured Vascular Endothelial Cells
Levon M. Khachigian;Amy J. Williams;Tucker Collins.
Journal of Biological Chemistry (1995)
Sp1 Phosphorylation and Its Regulation of Gene Transcription
Nicole Y. Tan;Levon M. Khachigian.
Molecular and Cellular Biology (2009)
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