D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 64 Citations 13,725 165 World Ranking 4284 National Ranking 103

Research.com Recognitions

Awards & Achievements

2003 - Gottschalk Medal, Australian Academy of Science

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His primary scientific interests are in Cell biology, Transcription factor, Gene expression, Promoter and Molecular biology. He has researched Cell biology in several fields, including Vascular smooth muscle, Internal medicine, Endothelium, Platelet-derived growth factor and Response element. His research in Transcription factor intersects with topics in Regulation of gene expression, Transcription and In vivo.

As part of the same scientific family, Levon M. Khachigian usually focuses on Gene expression, concentrating on Growth factor and intersecting with TATA box. His Promoter research is multidisciplinary, incorporating perspectives in Cellular differentiation and DNA-binding protein. His Molecular biology research incorporates themes from Vascular endothelial growth factor A, Gene, Zinc finger and Transactivation.

His most cited work include:

  • A promoter-level mammalian expression atlas (1307 citations)
  • Egr-1-Induced Endothelial Gene Expression: A Common Theme in Vascular Injury (496 citations)
  • Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells (378 citations)

What are the main themes of his work throughout his whole career to date?

Cell biology, Molecular biology, Transcription factor, Internal medicine and Cancer research are his primary areas of study. Levon M. Khachigian interconnects Gene expression, Cell growth, Vascular smooth muscle, Growth factor and Fibroblast growth factor in the investigation of issues within Cell biology. His Molecular biology research integrates issues from Zinc finger, Platelet-derived growth factor, Platelet-derived growth factor receptor, Messenger RNA and Transcription.

His Transcription factor research includes elements of Promoter and Regulation of gene expression. His work carried out in the field of Internal medicine brings together such families of science as Endocrinology and Cardiology. His Cancer research study which covers Dz13 that intersects with Pathology.

He most often published in these fields:

  • Cell biology (27.31%)
  • Molecular biology (25.77%)
  • Transcription factor (20.77%)

What were the highlights of his more recent work (between 2012-2021)?

  • Internal medicine (18.46%)
  • Cancer research (15.77%)
  • Cell biology (27.31%)

In recent papers he was focusing on the following fields of study:

Levon M. Khachigian focuses on Internal medicine, Cancer research, Cell biology, Transcription factor and Cardiology. Levon M. Khachigian combines subjects such as Oncology and Pathology with his study of Internal medicine. The various areas that Levon M. Khachigian examines in his Cancer research study include Inflammation, c-jun and Vascular permeability.

His studies in Cell biology integrate themes in fields like Endothelial stem cell, Gene expression, Vascular smooth muscle, Chromatin and Endothelium. Within one scientific family, Levon M. Khachigian focuses on topics pertaining to Promoter under Transcription factor, and may sometimes address concerns connected to Transcription. Levon M. Khachigian works mostly in the field of Transcription, limiting it down to topics relating to Regulation of gene expression and, in certain cases, Molecular biology and Computational biology, as a part of the same area of interest.

Between 2012 and 2021, his most popular works were:

  • A promoter-level mammalian expression atlas (1307 citations)
  • Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells (378 citations)
  • FANTOM5 CAGE profiles of human and mouse samples (82 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

Levon M. Khachigian focuses on Regulation of gene expression, Internal medicine, microRNA, Cancer research and Transcription factor. His work deals with themes such as Promoter, Cap analysis gene expression and Molecular biology, which intersect with Regulation of gene expression. His study in Promoter is interdisciplinary in nature, drawing from both Enhancer and Transcription.

Review article, Clinical efficacy and Kidney is closely connected to Cardiology in his research, which is encompassed under the umbrella topic of Internal medicine. His Cancer research study combines topics from a wide range of disciplines, such as Zinc finger transcription factor, Inflammation, Interferon and VE-cadherin. As part of his studies on Transcription factor, he often connects relevant subjects like Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A promoter-level mammalian expression atlas

Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie.
Nature (2014)

1134 Citations

Egr-1-Induced Endothelial Gene Expression: A Common Theme in Vascular Injury

Levon M. Khachigian;Volkhard Lindner;Amy J. Williams;Tucker Collins.
Science (1996)

629 Citations

Coronary in-stent restenosis: Current status and future strategies

Harry C Lowe;Stephen N Oesterle;Levon M Khachigian.
Journal of the American College of Cardiology (2002)

569 Citations

Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress.

Levon M. Khachigian;Nitzan Resnick;Michael A. Gimbrone;Tucker Collins.
Journal of Clinical Investigation (1995)

461 Citations

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

Erik Arner;Carsten O. Daub;Kristoffer Vitting-Seerup;Robin Andersson.
Science (2015)

397 Citations

DNAzyme targeting c-jun suppresses skin cancer growth

Hong Cai;Fernando S. Santiago;Leonel Prado-Lourenco;Bo Wang;Bo Wang.
Science Translational Medicine (2012)

367 Citations

Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth

Roger G Fahmy;Crispin R Dass;Lun-Quan Sun;Colin N Chesterman.
Nature Medicine (2003)

358 Citations

New DNA enzyme targeting Egr-1 mRNA inhibits vascular smooth muscle proliferation and regrowth after injury

Fernando S. Santiago;Harry C. Lowe;Mary M. Kavurma;Colin N. Chesterman.
Nature Medicine (1999)

342 Citations

Interplay of Sp1 and Egr-1 in the Proximal Platelet-derived Growth Factor A-Chain Promoter in Cultured Vascular Endothelial Cells

Levon M. Khachigian;Amy J. Williams;Tucker Collins.
Journal of Biological Chemistry (1995)

338 Citations

Sp1 Phosphorylation and Its Regulation of Gene Transcription

Nicole Y. Tan;Levon M. Khachigian.
Molecular and Cellular Biology (2009)

333 Citations

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