His primary areas of investigation include Immunology, Interleukin 5, Eotaxin, Eosinophilia and Inflammation. His study involves Eosinophil, Interleukin 13, Interleukin, Cytokine and T cell, a branch of Immunology. Klaus I. Matthaei combines subjects such as Peritoneal cavity and Lung with his study of Interleukin 5.
His work in Eotaxin addresses issues such as Bone marrow, which are connected to fields such as Pulmonary Eosinophilia, Macrophage inflammatory protein and Endocrinology. His Eosinophilia research is multidisciplinary, incorporating perspectives in Cellular differentiation, Ovalbumin, CD5, Antibody and Stem cell. The various areas that Klaus I. Matthaei examines in his Inflammation study include Sensitization, Eosinophil differentiation, Respiratory epithelium and Asthma.
The scientist’s investigation covers issues in Immunology, Interleukin 5, Eosinophil, Internal medicine and Endocrinology. His is involved in several facets of Immunology study, as is seen by his studies on Eosinophilia, Inflammation, Eotaxin, Interleukin 13 and Interleukin. His Eosinophilia research integrates issues from Immunoglobulin E, Aeroallergen and Ovalbumin.
His Interleukin 5 research entails a greater understanding of Cytokine. His work is dedicated to discovering how Eosinophil, Pathogenesis are connected with Asthma and other disciplines. His Endocrinology research includes elements of Receptor and Matrigel.
His scientific interests lie mostly in Internal medicine, Endocrinology, Immunology, Cell biology and Gene. The study incorporates disciplines such as Growth factor and Matrigel in addition to Endocrinology. His study in Immunology concentrates on Eosinophil, Interleukin 5, Nippostrongylus, Nippostrongylus brasiliensis and Secondary infection.
His work deals with themes such as Allergy and Allergic inflammation, which intersect with Eosinophil. Klaus I. Matthaei has researched Interleukin 5 in several fields, including Peritoneal cavity, Eotaxin, Interferon gamma, Cytokine receptor and BALB/c. As part of the same scientific family, he usually focuses on Wound healing, concentrating on Inflammation and intersecting with Cytokine, Eosinophilia, Infiltration, Cell migration and Cell signaling.
His primary scientific interests are in Immunology, Endocrinology, Internal medicine, Eosinophil and Interleukin 5. The study of Immunology is intertwined with the study of Signal transduction in a number of ways. His research in Endocrinology intersects with topics in Receptor, Epithelium, Interleukin 13 and Caco-2.
His Internal medicine research includes themes of Chloride channel, Cell biology and Cystic fibrosis transmembrane conductance regulator. His studies in Eosinophil integrate themes in fields like Secondary infection, House dust mite, Allergy, Allergic inflammation and Innate immune system. His Interleukin 5 research is multidisciplinary, relying on both STAT6, Eotaxin, Cellular immunity and Nippostrongylus brasiliensis, Nippostrongylus.
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Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model.
P S Foster;S P Hogan;A J Ramsay;K I Matthaei.
Journal of Experimental Medicine (1996)
The role of interleukin-6 in mucosal IgA antibody responses in vivo
Alistair J. Ramsay;Alan J. Husband;Ian A. Ramshaw;Shisan Bao.
Science (1994)
IL-5-Deficient Mice Have a Developmental Defect in CD5+ B-1 Cells and Lack Eosinophilia but Have Normal Antibody and Cytotoxic T Cell Responses
Manfred Kopf;Frank Brombacher;Philip D Hodgkin;Alistair J Ramsay.
Immunity (1996)
Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice.
A W Mould;K I Matthaei;I G Young;P S Foster.
Journal of Clinical Investigation (1997)
Histone variant H2A.Z is required for early mammalian development.
Renate Faast;Varaporn Thonglairoam;Thomas C Schulz;Jacquie Beall.
Current Biology (2001)
A Novel T Cell-Regulated Mechanism Modulating Allergen-Induced Airways Hyperreactivity in BALB/c Mice Independently of IL-4 and IL-5
Simon P. Hogan;Klaus I. Matthaei;Janine M. Young;Aulikki Koskinen.
Journal of Immunology (1998)
IL-13 induces eosinophil recruitment into the lung by an IL-5- and eotaxin-dependent mechanism.
Samuel M. Pope;Eric B. Brandt;Anil Mishra;Simon P. Hogan.
The Journal of Allergy and Clinical Immunology (2001)
IL-9– and mast cell–mediated intestinal permeability predisposes to oral antigen hypersensitivity
Elizabeth E. Forbes;Katherine Groschwitz;J. Pablo Abonia;Eric B. Brandt.
Journal of Experimental Medicine (2008)
Interleukin-5-producing CD4+ T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity, and lung damage in mice
Simon P. Hogan;Aulikki Koskinen;Klaus I. Matthaei;Ian G. Young.
American Journal of Respiratory and Critical Care Medicine (1998)
Elemental signals regulating eosinophil accumulation in the lung.
Paul S. Foster;Arne W. Mould;Ming Yang;Jason Mackenzie.
Immunological Reviews (2001)
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