Ian G. Young

Overview

Best Publications

• Sequence and organization of the human mitochondrial genome

  S. Anderson;A. T. Bankier;B. G. Barrell;M. H. L. de Bruijn

  14947
  Citations

• Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model.

  P S Foster;S P Hogan;A J Ramsay;K I Matthaei

  1697
  Citations

• Recombinant human interleukin 5 is a selective activator of human eosinophil function.

  Angel F. Lopez;Colin J. Sanderson;Jennifer R. Gamble;Hugh D. Campbell

  1428
  Citations

• IL-5-Deficient Mice Have a Developmental Defect in CD5+ B-1 Cells and Lack Eosinophilia but Have Normal Antibody and Cytotoxic T Cell Responses

  Manfred Kopf;Frank Brombacher;Philip D Hodgkin;Alistair J Ramsay

  739
  Citations

• Molecular cloning of cDNA for murine interleukin-3.

  M. C. Fung;A. J. Hapel;S. Ymer;D. R. Cohen

  626
  Citations

• Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin-5)

  Hugh D. Campbell;William Q. J. Tucker;Yvonne Hort;Mary E. Martinson

  431
  Citations

• Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice.

  A W Mould;K I Matthaei;I G Young;P S Foster

  427
  Citations

• Different pattern of codon recognition by mammalian mitochondrial tRNAs.

  B. G. Barrell;Stephen Anderson;A. T. Bankier;M. H. de Bruijn

  375
  Citations

• Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma.

  Joerg Mattes;Ming Yang;Surendran Mahalingam;Joachim Kuehr

  368
  Citations

• Constitutive synthesis of interleukin-3 by leukaemia cell line WEHI-3B is due to retroviral insertion near the gene.

  S. Ymer;W. Q. J. Tucker;C. J. Sanderson;A. J. Hapel

  363
  Citations

• A Novel T Cell-Regulated Mechanism Modulating Allergen-Induced Airways Hyperreactivity in BALB/c Mice Independently of IL-4 and IL-5

  Simon P. Hogan;Klaus I. Matthaei;Janine M. Young;Aulikki Koskinen

  352
  Citations

• Molecular and Cellular Biology of Eosinophil Differentiation Factor (Interleukin-5) and its Effects on Human and Mouse B Cells

  Colin J. Sanderson;Hugh D. Campbell;Ian G. Young

  349
  Citations

• Molecular organization of the cytokine gene cluster, involving the human IL-3, IL-4, IL-5, and GM-CSF genes, on human chromosome 5

  BH van Leeuwen;ME Martinson;GC Webb;IG Young

  302
  Citations

• Interleukin-5-producing CD4+ T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity, and lung damage in mice

  Simon P. Hogan;Aulikki Koskinen;Klaus I. Matthaei;Ian G. Young

  287
  Citations

• Elemental signals regulating eosinophil accumulation in the lung.

  Paul S. Foster;Arne W. Mould;Ming Yang;Jason Mackenzie

  280
  Citations

• Recombinant human interleukin 5 is an eosinophil differentiation factor but has no activity in standard human B cell growth factor assays.

  Elaine Clutterbuck;John G. Shields;John Gordon;Susan H. Smith

  229
  Citations

• Interleukin-13 Mediates Airways Hyperreactivity through the IL-4 Receptor-Alpha Chain and STAT-6 Independently of IL-5 and Eotaxin

  Ming Yang;Simon P. Hogan;Peter J. Henry;Klaus I. Matthaei

  227
  Citations

• Nucleotide sequence coding for the respiratory NADH dehydrogenase of Escherichia coli. UUG initiation codon.

  Ian G. Young;Bruce L. Rogers;Hugh D. Campbell;Anthony Jaworowski

  219
  Citations

• The effect of IL-5 and eotaxin expression in the lung on eosinophil trafficking and degranulation and the induction of bronchial hyperreactivity

  Arne W. Mould;Alistair J. Ramsay;Klaus I. Matthaei;Ian G. Young

  194
  Citations

• Eotaxin-2 and IL-5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperreactivity

  Ming Yang;Simon P Hogan;Surendran Mahalingam;Sam M Pope

  147
  Citations