World's Best Scientists 2026 revealed!
Mohamed-Ali Hakimi

Mohamed-Ali Hakimi

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
10029
World Ranking
16664
National Ranking
699

Overview

Mohamed-Ali Hakimi is affiliated with Grenoble Alpes University in France. Their research primarily spans the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Their work addresses key topics including Toxoplasma gondii research studies, herpesvirus infections and treatments, cytomegalovirus and herpesvirus research, RNA modifications and cancer, HIV research and treatment, parasitic infections and diagnostics, and RNA and protein synthesis mechanisms.

The scientist has contributed extensively to parasitology and related subfields such as epidemiology, molecular biology, and virology. Their publications appear frequently in venues including bioRxiv (Cold Spring Harbor Laboratory), PLoS Pathogens, Nature Microbiology, Cell Host & Microbe, and BMC Biology.

Mohamed-Ali Hakimi's recent papers include:

  • "A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment" (2020, Nature Microbiology)
  • "In vitro production of cat-restricted Toxoplasma pre-sexual stages" (2023, Nature)
  • "Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii" (2020, BMC Biology)
  • "The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages" (2022, Cell Host & Microbe)
  • "A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma" (2021, eLife)

Frequent collaborators include Christopher Swale, Alexandre Bougdour, Yohann Couté, Dayana C. Farhat, and Lucid Belmudes, reflecting ongoing partnerships that have contributed to multiple publications.

Publication venues where Mohamed-Ali Hakimi has contributed multiple works include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Pathogens
  • Nature Microbiology
  • Cell Host & Microbe
  • BMC Biology

The scientist's main fields of study and their associated publication counts are:

  • Immunology and Microbiology (35 publications)
  • Medicine (29 publications)
  • Biochemistry, Genetics and Molecular Biology (17 publications)

Within specialized subfields, Mohamed-Ali Hakimi focuses on:

  • Parasitology (28 publications)
  • Epidemiology (26 publications)
  • Molecular Biology (17 publications)
  • Virology (5 publications)
  • Electrical and Electronic Engineering (2 publications)

The scientist covers a broad range of research topics, including:

  • Toxoplasma gondii Research Studies (48 publications)
  • Herpesvirus Infections and Treatments (26 publications)
  • Cytomegalovirus and herpesvirus research (16 publications)
  • RNA modifications and cancer (12 publications)
  • HIV Research and Treatment (10 publications)
  • Parasitic Infections and Diagnostics (8 publications)
  • RNA and protein synthesis mechanisms (8 publications)

Best Publications

  • Integrator, a Multiprotein Mediator of Small Nuclear RNA Processing, Associates with the C-Terminal Repeat of RNA Polymerase II

    David Baillat;Mohamed Ali Hakimi;Anders M. Näär;Ali Shilatifard

  • Reinforcement of silencing at transposons and highly repeated sequences requires the concerted action of two distinct RNA polymerases IV in Arabidopsis

    Dominique Pontier;Galina Yahubyan;Danielle Vega;Agnès Bulski

  • Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components

    Mahmoud El-Shami;Dominique Pontier;Sylvie Lahmy;Laurence Braun

  • Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.

    Yuanshu Dong;Mohamed Ali Hakimi;Xiaowei Chen;Easwari Kumaraswamy

  • A chromatin remodelling complex that loads cohesin onto human chromosomes

    Mohamed-Ali Hakimi;Daniel A. Bochar;John A. Schmiesing;Yuanshu Dong

  • A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes

    Mohamed Ali Hakimi;Daniel A. Bochar;Josh Chenoweth;William S. Lane

  • Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein.

    Jacinthe Azevedo;Damien Garcia;Dominique Pontier;Stephanie Ohnesorge

  • Functional Interplay between Histone Demethylase and Deacetylase Enzymes

    Min Gyu Lee;Christopher Wynder;Daniel A. Bochar;Mohamed Ali Hakimi

  • Toxoplasma Effectors Targeting Host Signaling and Transcription

    Mohamed-Ali Hakimi;Philipp Olias;Philipp Olias;L. David Sibley

  • A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation

    Laurence Braun;Marie-Pierre Brenier-Pinchart;Marie-Pierre Brenier-Pinchart;Manickam Yogavel;Aurélie Curt-Varesano;Aurélie Curt-Varesano

  • A Candidate X-linked Mental Retardation Gene Is a Component of a New Family of Histone Deacetylase-containing Complexes*

    Mohamed Ali Hakimi;Yuanshu Dong;William S. Lane;David W. Speicher

  • Host Cell Subversion by Toxoplasma GRA16, an Exported Dense Granule Protein that Targets the Host Cell Nucleus and Alters Gene Expression

    Alexandre Bougdour;Eric Durandau;Eric Durandau;Marie-Pierre Brenier-Pinchart;Marie-Pierre Brenier-Pinchart;Philippe Ortet

  • The Toxoplasma dense granule proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole

    Daniel A. Gold;Aaron D. Kaplan;Agnieszka Lis;Glenna C.L. Bett

  • Effectors Targeting Host Signaling and Transcription.

    Mohamed-Ali Hakimi;Philipp Alexander Olias;L David Sibley

  • Histone-Modifying Complexes Regulate Gene Expression Pertinent to the Differentiation of the Protozoan Parasite Toxoplasma gondii†

    Nehmé Saksouk;Micah M. Bhatti;Sylvie Kieffer;Aaron T. Smith

  • Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites

    Alexandre Bougdour;Danièle Maubon;Patricia Baldacci;Philippe Ortet

  • Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ-mediated host defenses.

    Laurence Braun;Marie-Pierre Brenier-Pinchart;Julien Vollaire

  • Characterization of Arabidopsis plastid sigma-like transcription factors SIG1, SIG2 and SIG3.

    Isabelle Privat;Mohamed-Ali Hakimi;Laurence Buhot;Jean-Jacques Favory

  • A Complex Small RNA Repertoire Is Generated by a Plant/Fungal-Like Machinery and Effected by a Metazoan-Like Argonaute in the Single-Cell Human Parasite Toxoplasma gondii

    Laurence Braun;Dominique Cannella;Philippe Ortet;Mohamed Barakat

  • The aspartyl protease TgASP5 mediates the export of the Toxoplasma GRA16 and GRA24 effectors into host cells

    Aurélie Curt-Varesano;Aurélie Curt-Varesano;Laurence Braun;Laurence Braun;Caroline Ranquet;Mohamed-Ali Hakimi;Mohamed-Ali Hakimi

Frequent Co-Authors

Yohann Couté
Yohann Couté Grenoble Alpes University
Ramin Shiekhattar
Ramin Shiekhattar University of Miami
Dominique Pontier
Dominique Pontier Claude Bernard University Lyon 1
Jérôme Garin
Jérôme Garin CEA Grenoble
Jeroen P. J. Saeij
Jeroen P. J. Saeij University of California, Davis
David W. Speicher
David W. Speicher The Wistar Institute
Steven E. Jacobsen
Steven E. Jacobsen University of California, Los Angeles
L. David Sibley
L. David Sibley Washington University in St. Louis
William J. Sullivan
William J. Sullivan Indiana University

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