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Biology and Biochemistry

D-Index
49
Citations
16903
World Ranking
17830
National Ranking
7296

Overview

Jeroen P. J. Saeij is affiliated with the University of California, Davis in the United States. Their research focuses primarily on immunology and microbiology, with substantial contributions in medicine. Key subfields include epidemiology, parasitology, molecular biology, immunology, and virology.

The scientist's work extensively covers topics related to Toxoplasma gondii research studies, herpesvirus infections and treatments, cytomegalovirus and herpesvirus research, inflammasome and immune disorders, rabies epidemiology and control, interferon and immune responses, as well as heme oxygenase-1 and carbon monoxide.

Recent publications by Jeroen P. J. Saeij include:

  • Identification of a Master Regulator of Differentiation in Toxoplasma, 2020, Cell
  • Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection, 2020, Frontiers in Cellular and Infection Microbiology
  • Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNγ-activated murine macrophages, 2020, Nature Communications
  • Toxoplasma Mechanisms for Delivery of Proteins and Uptake of Nutrients Across the Host-Pathogen Interface, 2020, Annual Review of Microbiology
  • The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages, 2022, Cell Host & Microbe

Frequent collaborators of this scientist include:

  • Lamba Omar Sangaré
  • David Arranz-Solís
  • Debanjan Mukhopadhyay
  • Tatiana C. Paredes-Santos
  • Mohamed-Ali Hakimi

Jeroen P. J. Saeij has published multiple times in well-known academic venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio
  • PLoS Pathogens
  • Frontiers in Cellular and Infection Microbiology
  • Nature Communications

The scientist's research incorporates a diverse range of topics within infectious disease biology and host-pathogen interactions, with a notable emphasis on the molecular and immune-related mechanisms that underlie infections by Toxoplasma gondii and various herpesviruses.

Best Publications

  • Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

    Peter J Murray;Judith E Allen;Subhra K Biswas;Edward A Fisher

  • A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes.

    Saima M. Sidik;Diego Huet;Suresh M. Ganesan;My Hang Huynh

  • Polymorphic Secreted Kinases Are Key Virulence Factors in Toxoplasmosis

    Jeroen Saeij;J. P. Boyle;S. Coller;S. Taylor

  • Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue

    Jeroen Saeij;S. Coller;J. P. Boyle;M. E. Jerome

  • Strain-specific activation of the NF-κB pathway by GRA15, a novel Toxoplasma gondii dense granule protein

    Emily Elizabeth Rosowski;Diana Lu;Lindsay Julien;Lauren B. Rodda

  • Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host.

    Jeroen P.J. Saeij;Jon P. Boyle;John C. Boothroyd

  • Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence

    Ira J. Blader;Jeroen P. Saeij

  • Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes

    Hernan Lorenzi;Asis Khan;Asis Khan;Michael S Behnke;Michael S Behnke;Sivaranjani Namasivayam

  • Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to Toxoplasma gondii

    Gezahegn Gorfu;Kimberly Cirelli;Mariane Bandeira Melo;Katrin Mayer-Barber

  • Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains

    Jeroen P. J. Saeij;Jon P. Boyle;Michael E. Grigg;Michael E. Grigg;Gustavo Arrizabalaga

  • Toxoplasma Polymorphic Effectors Determine Macrophage Polarization and Intestinal Inflammation

    Kirk D.C. Jensen;Yiding Wang;Yiding Wang;Elia D. Tait Wojno;Anjali J. Shastri

  • The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.

    Wendy Niedelman;Daniel A. Gold;Emily E. Rosowski;Joris K. Sprokholt;Joris K. Sprokholt

  • The Toxoplasma dense granule proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole

    Daniel A. Gold;Aaron D. Kaplan;Agnieszka Lis;Glenna C.L. Bett

  • Toxoplasma gondii effectors are master regulators of the inflammatory response

    Mariane Bandeira Melo;Kirk D. C. Jensen;Jeroen Saeij

  • Identification of a Master Regulator of Differentiation in Toxoplasma

    Benjamin S. Waldman;Dominic Schwarz;Dominic Schwarz;Marc H. Wadsworth;Marc H. Wadsworth;Marc H. Wadsworth;Jeroen P. Saeij

  • Molecular and functional characterization of carp TNF: a link between TNF polymorphism and trypanotolerance?

    Jeroen P.J Saeij;René J.M Stet;Beja J de Vries;Willem B van Muiswinkel

  • Molecular and functional characterization of a fish inducible-type nitric oxide synthase.

    J. P. J. Saeij;R. J. M. Stet;A. Groeneveld;L.B.M. Verburg-van Kemenade

  • Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii

    Jon P. Boyle;Badri Rajasekar;Jeroen P. J. Saeij;James W. Ajioka

  • Comprehensive analysis of forty yeast microarray datasets reveals a novel subset of genes (APha-RiB) consistently negatively associated with ribosome biogenesis

    Basel Abu-Jamous;Rui Fa;David J Roberts;David J Roberts;Asoke K Nandi;Asoke K Nandi

  • A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes

    Saima M. Sidik;Diego Huet;My-Hang Huynh;Prathapan Thiru

Frequent Co-Authors

John C. Boothroyd
John C. Boothroyd Stanford University
Michael E. Grigg
Michael E. Grigg National Institutes of Health
Mohamed-Ali Hakimi
Mohamed-Ali Hakimi Grenoble Alpes University
Michael W. White
Michael W. White University of South Florida
Mahtab Moayeri
Mahtab Moayeri National Institutes of Health
Stephen H. Leppla
Stephen H. Leppla National Institutes of Health
Gregory A. Taylor
Gregory A. Taylor Duke University
L. David Sibley
L. David Sibley Washington University in St. Louis

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