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Molecular Biology

D-Index
51
Citations
13438
World Ranking
2480
National Ranking
166

Overview

Gunnar Schotta is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with additional contributions in medicine.

The main fields of study for their work include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

The scientist's research activities extend into several subfields, notably:

  • Molecular Biology
  • Immunology
  • Oncology
  • Plant Science
  • Cancer Research

Main topics addressed in their publications include:

  • Epigenetics and DNA Methylation
  • Chromosomal and Genetic Variations
  • RNA Modifications and Cancer
  • Genomics and Chromatin Dynamics
  • DNA and Nucleic Acid Chemistry
  • Advanced Biosensing and Bioanalysis Techniques
  • RNA Interference and Gene Delivery

Recently published papers by Gunnar Schotta highlight their engagement with diverse aspects of molecular biology and gene regulation. Notable recent works include:

  • "Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome" (2021, Nature Communications)
  • "HIV-1 infection activates endogenous retroviral promoters regulating antiviral gene expression" (2020, Nucleic Acids Research)
  • "Epithelial cell plasticity drives endoderm formation during gastrulation" (2021, Nature Cell Biology)
  • "SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation" (2020, Gut)
  • "The Kidney Contains Ontogenetically Distinct Dendritic Cell and Macrophage Subtypes throughout Development That Differ in Their Inflammatory Properties" (2020, Journal of the American Society of Nephrology)

The scientist regularly publishes in several journals, with frequent publication venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nucleic Acids Research
  • Pancreatology
  • Nature Cell Biology

Gunnar Schotta has established collaborations with several co-authors, some of the most frequent being:

  • Filippo M. Cernilogar
  • Tobias Straub
  • Axel Imhof
  • Andrea Terrasi
  • Maryam Kazerani

Best Publications

  • Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

    Mario F Fraga;Esteban Ballestar;Ana Villar-Garea;Manuel Boix-Chornet

  • A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

    Gunnar Schotta;Monika Lachner;Kavitha Sarma;Anja Ebert

  • Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing.

    Gunnar Schotta;Anja Ebert;Veiko Krauss;Andreas Fischer

  • Functional mammalian homologues of the Drosophila PEV‐modifier Su(var)3‐9 encode centromere‐associated proteins which complex with the heterochromatin component M31

    Louise Aagaard;Götz Laible;Philipp Selenko;Manfred Schmid

  • A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

    Gunnar Schotta;Roopsha Sengupta;Roopsha Sengupta;Stefan Kubicek;Stephen Malin

  • Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells

    Barna D. Fodor;Stefan Kubicek;Masato Yonezawa;Roderick J. O’Sullivan

  • Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

    Susana Gonzalo;Marta García-Cao;Mario F. Fraga;Gunnar Schotta

  • Histone H4 Lysine 20 methylation: key player in epigenetic regulation of genomic integrity

    Stine Jørgensen;Gunnar Schotta;Claus Storgaard Sørensen

  • Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila

    Anja Ebert;Gunnar Schotta;Sandro Lein;Stefan Kubicek

  • Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination

    Roberta Benetti;Susana Gonzalo;Isabel Jaco;Gunnar Schotta

  • Position-effect variegation and the genetic dissection of chromatin regulation in Drosophila

    Gunnar Schotta;Anja Ebert;Rainer Dorn;Gunter Reuter

  • Histone modification and the control of heterochromatic gene silencing in Drosophila.

    Anja Ebert;Sandro Lein;Gunnar Schotta;Gunter Reuter

  • Physical and functional association of SU(VAR)3-9 and HDAC1 in Drosophila.

    Birgit Czermin;Gunnar Schotta;Bastian B Hülsmann;Alexander Brehm

  • Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome.

    Sara Lago;Matteo Nadai;Filippo M. Cernilogar;Maryam Kazerani

  • Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome.

    Kakkad Regha;Mathew A. Sloane;Ru Huang;Florian M. Pauler

  • Quiescence-Induced LncRNAs Trigger H4K20 Trimethylation and Transcriptional Silencing

    Holger Bierhoff;Marcel Andre Dammert;David Brocks;Silvia Dambacher

  • Atrx promotes heterochromatin formation at retrotransposons

    Dennis Sadic;Katharina Schmidt;Sophia Groh;Ivan Kondofersky

  • Genetic and Molecular Complexity of the Position Effect Variegation Modifier mod(mdg4) in Drosophila

    Kerstin Büchner;Peggy Roth;Gunnar Schotta;Veiko Krauss

  • Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin

    Matthias Hahn;Silvia Dambacher;Stanimir Dulev;Anastasia Yurievna Kuznetsova

  • Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

    S. Lago;F. M. Cernilogar;M. Kazerani;H. Dominiguez Moreno

Frequent Co-Authors

Thomas Jenuwein
Thomas Jenuwein Max Planck Society
Gunter Reuter
Gunter Reuter Martin Luther University Halle-Wittenberg
Matthias Hahn
Matthias Hahn Technical University of Kaiserslautern
Tobias Straub
Tobias Straub Ludwig-Maximilians-Universität München
Heinrich Leonhardt
Heinrich Leonhardt Ludwig-Maximilians-Universität München
Wolfgang Hiddemann
Wolfgang Hiddemann Ludwig-Maximilians-Universität München
Martin Irmler
Martin Irmler University of Lausanne
Karsten Rippe
Karsten Rippe German Cancer Research Center
Johannes Beckers
Johannes Beckers Technical University of Munich
Axel Kallies
Axel Kallies University of Melbourne

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