World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
12905
World Ranking
17467
National Ranking
7170

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Anthony J. Muslin is affiliated with Washington University in St. Louis in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology, Public Health, Environmental and Occupational Health, Endocrinology, Diabetes and Metabolism, Endocrine and Autonomic Systems, and Physiology.

The scientist's work is concentrated on several main topics, including:

  • Sphingolipid Metabolism and Signaling
  • Pregnancy-related medical research
  • Injury Epidemiology and Prevention
  • Circadian rhythm and melatonin
  • Ion Transport and Channel Regulation
  • Lipid Membrane Structure and Behavior
  • Inflammasome and immune disorders

Several recent papers highlight their contributions to the understanding of endothelial protection and receptor signaling. These include:

  • "A G protein-biased S1P 1 agonist, SAR247799, protects endothelial cells without affecting lymphocyte numbers" (2020), published in Science Signaling
  • "First-in-human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple oral doses of SAR247799, a selective G-protein-biased sphingosine-1 phosphate receptor-1 agonist for endothelial protection" (2020), published in British Journal of Clinical Pharmacology
  • "Endothelial-protective effects of a G-protein-biased sphingosine-1 phosphate receptor-1 agonist, SAR247799, in type-2 diabetes rats and a randomized placebo-controlled patient trial" (2020), published in British Journal of Clinical Pharmacology
  • "RGS4 inhibits angiotensin II signaling and macrophage localization during renal reperfusion injury independent of vasospasm" (2020), published in UNC Libraries
  • "Endothelial-protective effects of a G-protein-biased sphingosine-1 phosphate receptor-1 agonist, SAR247799, in type-2 diabetes rats and a randomized placebo-controlled patient trial." (2020), published in bioRxiv (Cold Spring Harbor Laboratory)

Frequent coauthors collaborating with Anthony J. Muslin include Ashfaq A. Parkar, Bruno Poirier, Philip Janiak, L. Bergougnan, and Agnes Tardat.

Muslin's work has appeared most often in the following publication venues:

  • British Journal of Clinical Pharmacology
  • Science Signaling
  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation

The scientist has been recognized as a Member of the Association of American Physicians. Their research contributions are documented across studies in vascular biology, receptor signaling, and clinical pharmacology.

Best Publications

  • Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine.

    Anthony J Muslin;Anthony J Muslin;J.William Tanner;Paul M Allen;Andrey S Shaw

  • Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

    Dave Jacobs;Danielle Glossip;Heming Xing;Anthony J. Muslin

  • Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

    Qianjin Hu;Anke Klippel;Anthony J. Muslin;Wendy J. Fantl

  • Akt1 Is Required for Physiological Cardiac Growth

    Brian DeBosch;Iya Treskov;Traian S. Lupu;Carla Weinheimer

  • MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets

    Anthony J. Muslin

  • Activation of Raf-1 by 14-3-3 proteins.

    Wendy J. Fantl;Anthony J. Muslin;Anthony J. Muslin;Akira Kikuchi;Jay A. Martin

  • Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice

    Scott P. Heximer;Russell H. Knutsen;Xiaoguang Sun;Kevin M. Kaltenbronn

  • 14-3-3 proteins block apoptosis and differentially regulate MAPK cascades

    Heming Xing;Shaosong Zhang;Carla Weinheimer;Attila Kovacs

  • HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint.

    Takumi Kawabe;Anthony J. Muslin;Stanley J. Korsmeyer

  • Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF

    Angus M. MacNicol;Anthony J. Muslin;Lewis T. Williams

  • ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome

    Jochen G. Schneider;Brian N. Finck;Jie Ren;Kara N. Standley

  • The role of the Grb2–p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis

    Shaosong Zhang;Carla Weinheimer;Michael Courtois;Attila Kovacs

  • Spontaneously hypertensive rat vascular smooth muscle cells in culture exhibit increased growth and Na+/H+ exchange.

    B C Berk;G Vallega;A J Muslin;H M Gordon

  • The protein kinase KSR interacts with 14-3-3 protein and Raf

    Heming Xing;Kerry Kornfeld;Anthony J. Muslin

  • Raf-1 Kinase Is Required for Cardiac Hypertrophy and Cardiomyocyte Survival in Response to Pressure Overload

    Ian S. Harris;Shaosong Zhang;Ilya Treskov;Attila Kovacs

  • RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload

    Jason H. Rogers;Praveen Tamirisa;Attila Kovacs;Carla Weinheimer

  • Akt2 Regulates Cardiac Metabolism and Cardiomyocyte Survival

    Brian J. DeBosch;Nandakumar Sambandam;Carla S. Weinheimer;Michael Courtois

  • Zinc Ions and Cation Diffusion Facilitator Proteins Regulate Ras-Mediated Signaling

    Janelle J. Bruinsma;Tanawat Jirakulaporn;Anthony J. Muslin;Kerry Kornfeld

  • Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos.

    A J Muslin;A M MacNicol;L T Williams

  • Role of p38alpha MAPK in cardiac apoptosis and remodeling after myocardial infarction.

    Jie Ren;Shaosong Zhang;Attila Kovacs;Yibin Wang

Frequent Co-Authors

Lewis T. Williams
Lewis T. Williams University of California, San Francisco
Yoshifusa Aizawa
Yoshifusa Aizawa Tachikawa Medical Center
Kendall J. Blumer
Kendall J. Blumer Washington University in St. Louis
Akira Kikuchi
Akira Kikuchi Osaka University
Yibin Wang
Yibin Wang University of California, Los Angeles
Clay F. Semenkovich
Clay F. Semenkovich Washington University in St. Louis
Hidenori Ichijo
Hidenori Ichijo University of Tokyo
Ulrich H. von Andrian
Ulrich H. von Andrian Harvard University
Brian N. Finck
Brian N. Finck Washington University in St. Louis

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