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Overview

David M. Dorfman is affiliated with Harvard Medical School in the United States, with a research focus primarily in the medical sciences. Their work spans several subfields including hematology, molecular biology, genetics, oncology, and pathology and forensic medicine.

The research topics David M. Dorfman has published on include:

  • Multiple Myeloma Research and Treatments
  • Lymphoma Diagnosis and Treatment
  • Chronic Lymphocytic Leukemia Research
  • Protein Degradation and Inhibitors
  • Peptidase Inhibition and Analysis
  • Acute Myeloid Leukemia Research
  • Advanced Breast Cancer Therapies

David M. Dorfman has contributed to several peer-reviewed research papers, with recent publications as follows:

  • Combination therapy targeting Erk1/2 and CDK4/6i in relapsed refractory multiple myeloma, 2022, Leukemia
  • Laboratory Workup of Lymphoma in Adults: Guideline From the American Society for Clinical Pathology and the College of American Pathologists, 2020, Archives of Pathology & Laboratory Medicine
  • Laboratory Workup of Lymphoma in Adults, 2020, American Journal of Clinical Pathology
  • miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms, 2021, Blood
  • Heterogeneity of B cell lymphopoiesis in patients with premalignant and active myeloma, 2023, JCI Insight

The scientist frequently publishes in the following venues:

  • Blood
  • Archives of Pathology & Laboratory Medicine
  • Leukemia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Lymphoma Myeloma & Leukemia

Frequent co-authors collaborating with David M. Dorfman include:

  • Kenneth C. Anderson
  • Teru Hideshima
  • Sophia Adamia
  • Zuzana Chyra
  • Yu-Tzu Tai

The scope of their research mainly focuses on the understanding and treatment development for various hematologic malignancies, particularly multiple myeloma and lymphoma. Their publications reflect ongoing engagement with disease mechanisms and therapeutic strategies across related cancers.

Best Publications

  • Blockade of Programmed Death-1 Ligands on Dendritic Cells Enhances T Cell Activation and Cytokine Production

    Julia A. Brown;David M. Dorfman;Feng-Rong Ma;Elizabeth L. Sullivan

  • TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.

    Norimoto Kobayashi;Piia Karisola;Victor Peña-Cruz;David M. Dorfman

  • A targeted mutational landscape of angioimmunoblastic T-cell lymphoma

    Oreofe Odejide;Oliver Weigert;Oliver Weigert;Andrew A. Lane;Dan Toscano

  • Highly efficient therapeutic gene editing of human hematopoietic stem cells.

    Yuxuan Wu;Jing Zeng;Jing Zeng;Benjamin P. Roscoe;Pengpeng Liu

  • Programmed death-1 (PD-1) is a marker of germinal center-associated T cells and angioimmunoblastic T-cell lymphoma

    David M. Dorfman;Julia A. Brown;Aliakbar Shahsafaei;Gordon J. Freeman

  • Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells.

    D. M. Dorfman;D. B. Wilson;G. A. P. Bruns;S. H. Orkin

  • Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation.

    Kathryn T. Hall;Laurence Boumsell;Joachim L. Schultze;Vassiliki A. Boussiotis

  • Impact of Efavirenz on Neuropsychological Performance and Symptoms in HIV-Infected Individuals

    David B. Clifford;Scott Evans;Yijun Yang;Edward P. Acosta

  • The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

    Elizabeth C. Townsend;Mark A. Murakami;Alexandra Christodoulou;Amanda L. Christie

  • Bioinspired multivalent DNA network for capture and release of cells

    Weian Zhao;Cheryl Cui;Suman Bose;Dagang Guo

  • Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma

    Güllü Topal Görgün;Mehmet K. Samur;Kristen B. Cowens;Steven Paula

  • Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-Like proteins

    Frederick L. Moore;Jadwiga Jaruzelska;Jadwiga Jaruzelska;Mark S. Fox;Jun Urano

  • HIV-associated distal sensory polyneuropathy in the era of highly active antiretroviral therapy: the Manhattan HIV Brain Bank.

    Susan Morgello;Lydia Estanislao;David Simpson;Anthony Geraci

  • Solitary fibrous tumor of the orbit.

    David Dorfman;King To;G. Dickersin;Andrew Rosenberg

  • A brain imaging (single photon emission computerized tomography) study of semantic and affective processing in psychopaths

    Joanne Intrator;Joanne Intrator;Robert Hare;Peter Stritzke;Kirsten Brichtswein

  • Type 3 iodothyronine deiodinase is highly expressed in the human uteroplacental unit and in fetal epithelium.

    Stephen A. Huang;David M. Dorfman;David R. Genest;Domenico Salvatore

  • DAZ Family Proteins Exist Throughout Male Germ Cell Development and Transit from Nucleus to Cytoplasm at Meiosis in Humans and Mice

    Renee A. Reijo;David M. Dorfman;Roger Slee;Andrew A. Renshaw

  • The chemokine receptor CXCR3 is expressed in a subset of B-cell lymphomas and is a marker of B-cell chronic lymphocytic leukemia.

    Dan Jones;Richard J. Benjamin;Aliakbar Shahsafaei;David M. Dorfman

  • Screening and brief intervention to reduce marijuana use among youth and young adults in a pediatric emergency department.

    Elizabeth Bernstein;Erika Edwards;David Dorfman;Timothy Heeren

  • A Targeted Mutational Landscape of Angioimmunoblastic T-Cell Lymphoma: Association Between Advanced Age and Mutations in TET2 and DNMT3A

    Oliver Weigert;Nadja Kopp;Sudha Bolla;Oreofe Odejide

Frequent Co-Authors

Gordon J. Freeman
Gordon J. Freeman Harvard University
Rafi Ahmed
Rafi Ahmed Emory University
Teru Hideshima
Teru Hideshima Harvard University
Geraldine S. Pinkus
Geraldine S. Pinkus Brigham and Women's Hospital
Scott J. Rodig
Scott J. Rodig Harvard University
Kenneth C. Anderson
Kenneth C. Anderson Harvard University
Arlene H. Sharpe
Arlene H. Sharpe Harvard University
Stuart H. Orkin
Stuart H. Orkin Harvard University
Paul G. Richardson
Paul G. Richardson Harvard University
Jon C. Aster
Jon C. Aster Harvard Medical School

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