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Biology and Biochemistry

D-Index
99
Citations
52031
World Ranking
1560
National Ranking
877

Overview

J. Thomas Parsons is affiliated with the University of Virginia in the United States. Their research primarily spans the field of Medicine, with a focus on several subfields including Epidemiology, Infectious Diseases, and Molecular Biology.

Their work addresses topics such as Respiratory viral infections research, Viral Infections and Vectors, Virology and Viral Diseases, and CRISPR and Genetic Engineering.

Among recent publications attributed to Parsons, one titled "Human Parainfluenza Virus (HPIV) Detection in Hospitalized Children with Acute Respiratory Tract Infection in the Western Cape, South Africa during 2014-2022 Reveals a Shift in Dominance of HPIV 3 and 4 Infections" was published in 2023 in the journal Diagnostics. This paper examines shifts in the prevalence of distinct HPIV types in a pediatric population over several years.

Parsons is also associated as a co-author with other research papers published in 2025, related to multiomic CRISPR screening techniques in single-cell biology. These include "Simultaneous single-cell CRISPR, RNA, and ATAC-seq enables multiomic CRISPR screens to identify gene regulatory relationships" in bioRxiv (Cold Spring Harbor Laboratory), and "Simultaneous capture of single cell RNA-seq, ATAC-seq, and CRISPR perturbation enables multiomic screens to identify gene regulatory relationships" published in Cell Reports Methods. These contributions explore advanced integrated methods for gene regulatory analysis using CRISPR perturbations at the single-cell level.

Frequent co-authors working with Parsons include Kaivalya Shevade, Yeqing Angela Yang, Kevin Feng, K. Mäder, and Volkan Sevi̇m, each appearing in multiple joint publications.

Parsons' publications appear predominantly in these venues:

  • Diagnostics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports Methods

Best Publications

  • Cell migration: integrating signals from front to back.

    Anne J. Ridley;Martin A. Schwartz;Keith Burridge;Richard A. Firtel

  • Cell adhesion: integrating cytoskeletal dynamics and cellular tension

    J. Thomas Parsons;Alan Rick Horwitz;Martin A. Schwartz

  • pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

    M D Schaller;C A Borgman;B S Cobb;R R Vines

  • Focal adhesion kinase: the first ten years

    J. Thomas Parsons

  • FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly.

    Donna J. Webb;Karen Donais;Leanna A. Whitmore;Sheila M. Thomas

  • Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

    M D Schaller;J D Hildebrand;J D Shannon;J W Fox

  • Src family kinases, key regulators of signal transduction

    Sarah J Parsons;J Thomas Parsons

  • Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase.

    L Kornberg;H S Earp;J T Parsons;M Schaller

  • Adhesion assembly, disassembly and turnover in migrating cells -- over and over and over again.

    Donna J. Webb;J. Thomas Parsons;Alan F. Horwitz

  • Focal Adhesion Kinase: a regulator of focal adhesion dynamics and cell movement

    J T Parsons;K H Martin;J K Slack;J M Taylor

  • Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains.

    M D Schaller;C A Otey;J D Hildebrand;J T Parsons

  • Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets.

    L Lipfert;B Haimovich;M D Schaller;B S Cobb

  • pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk.

    M D Schaller;J T Parsons

  • HDAC6 Modulates Cell Motility by Altering the Acetylation Level of Cortactin

    Xiaohong Zhang;Zhigang Yuan;Yingtao Zhang;Sarah Yong

  • Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

    B. S. Cobb;M. D. Schaller;Tzeng-Horng Leu;J. T. Parsons

  • Focal adhesion kinase and associated proteins

    M D Schaller;J T Parsons

  • Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation.

    Alissa M. Weaver;Andrei V. Karginov;Andrew W. Kinley;Scott A. Weed

  • Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex.

    Hong Wu;J. T. Parsons

  • Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.

    S B Kanner;A B Reynolds;R R Vines;J T Parsons

  • Cellular characterization of a novel focal adhesion kinase inhibitor.

    Jill K. Slack-Davis;Karen H. Martin;Robert W. Tilghman;Marcin Iwanicki

Frequent Co-Authors

Jason A. Papin
Jason A. Papin University of Virginia
John A. Cooper
John A. Cooper Washington University in St. Louis
Sarah J. Parsons
Sarah J. Parsons University of Virginia
Michael D. Schaller
Michael D. Schaller West Virginia University
Alissa M. Weaver
Alissa M. Weaver Vanderbilt University
Martin A. Schwartz
Martin A. Schwartz Yale University
Jay W. Fox
Jay W. Fox University of Virginia
Alan Richardson
Alan Richardson Commonwealth Scientific and Industrial Research Organisation
Wen Cheng Xiong
Wen Cheng Xiong Case Western Reserve University

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