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Immunology

D-Index
59
Citations
11754
World Ranking
3437
National Ranking
234

Overview

Ulrike Koehl is affiliated with Leipzig University in Germany and has contributed extensively to the fields of medicine, immunology and microbiology, as well as biochemistry, genetics, and molecular biology.

The scientist's research spans several key subfields including oncology, immunology, molecular biology, genetics, and biomedical engineering.

Central topics of their work include:

  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Viral Infectious Diseases and Gene Expression in Insects
  • Virus-based gene therapy research
  • T-cell and B-cell Immunology
  • Biosimilars and Bioanalytical Methods
  • Immunotherapy and Immune Responses

Ulrike Koehl has collaborated frequently with other researchers such as Stephan Fricke, Uwe Platzbecker, Kristin Reiche, Andreas Boldt, and Vladan Vučinić, with collaboration counts ranging from 15 to 24 joint publications.

Their research has appeared most often in the following peer-reviewed journals and publication venues:

  • Frontiers in Immunology
  • Cancers
  • Blood
  • Molecular Therapy - Methods & Clinical Development
  • International Journal of Molecular Sciences

Significant recent papers by Koehl include:

  • Potential solutions for manufacture of CAR T cells in cancer immunotherapy, 2022, Nature Communications
  • High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia, 2020, Frontiers in Immunology
  • New Approaches for the Treatment of Chronic Graft-Versus-Host Disease: Current Status and Future Directions, 2020, Frontiers in Immunology
  • Lipid nanoparticles outperform electroporation in mRNA-based CAR T cell engineering, 2023, Molecular Therapy - Methods & Clinical Development
  • CAR T cells for treating autoimmune diseases, 2023, RMD Open

Best Publications

  • Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

    Marion G Ott;Manfred Schmidt;Kerstin Schwarzwaelder;Stefan Stein

  • Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease

    Stefan Stein;Marion G. Ott;Stephan Schultze-Strasser;Anna Jauch

  • Treatment of patients with advanced cancer with the natural killer cell line NK-92

    Torsten Tonn;Torsten Tonn;Dirk Schwabe;Hans G. Klingemann;Sven Becker;Sven Becker

  • New insights to the MLL recombinome of acute leukemias

    C. Meyer;E. Kowarz;J. Hofmann;A. Renneville

  • The MLL recombinome of acute leukemias.

    C. Meyer;B. Schneider;S. Jakob;S. Strehl

  • Advantages and applications of CAR-expressing natural killer cells.

    Wolfgang Glienke;Ruth Esser;Christoph Priesner;Julia D. Suerth

  • 111In-Labeled CD34+ Hematopoietic Progenitor Cells in a Rat Myocardial Infarction Model

    Winfried Brenner;Alexandra Aicher;Thomas Eckey;Schirin Massoudi

  • Ex vivo pretreatment of bone marrow mononuclear cells with endothelial NO synthase enhancer AVE9488 enhances their functional activity for cell therapy

    Ken Ichiro Sasaki;Christopher Heeschen;Alexandra Aicher;Thomas Ziebart

  • Targeted Cell Entry of Lentiviral Vectors

    Sabrina Funke;Andrea Maisner;Michael D Mühlebach;Ulrike Koehl

  • CD271 antigen defines a subset of multipotent stromal cells with immunosuppressive and lymphohematopoietic engraftment-promoting properties

    Selim Kuçi;Zyrafete Kuçi;Hermann Kreyenberg;Erika Deak

  • NK cells engineered to express a GD2 -specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin.

    Ruth Esser;Tina Müller;Dörthe Stefes;Stephan Kloess

  • Pre-emptive immunotherapy with purified natural killer cells after haploidentical SCT : a prospective phase II study in two centers

    M Stern;J R Passweg;S Meyer-Monard;R Esser

  • Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors

    Brigitte Anliker;Tobias Abel;Sabrina Kneissl;Juraj Hlavaty

  • IL-2 activated NK cell immunotherapy of three children after haploidentical stem cell transplantation.

    Ulrike Koehl;Jan Sörensen;Ruth Esser;Stefanie Zimmermann

  • Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol.

    Ulrike Koehl;Claudia Brehm;Sabine Huenecke;Stefanie Yvonne Zimmermann

  • Optimization of Human NK Cell Manufacturing: Fully Automated Separation, Improved Ex Vivo Expansion Using IL-21 with Autologous Feeder Cells, and Generation of Anti-CD123-CAR-Expressing Effector Cells.

    Stephan Klöß;Olaf Oberschmidt;Michael Morgan;Julia Dahlke

  • Generation of highly purified and functionally active human TH1 cells against Aspergillus fumigatus.

    Olaf Beck;Max S. Topp;Ulrike Koehl;Emmanuel Roilides

  • Activation of Epac stimulates integrin-dependent homing of progenitor cells

    Guillaume Carmona;Emmanouil Chavakis;Ulrike Koehl;Andreas M. Zeiher

  • Human natural killer cells exhibit direct activity against Aspergillus fumigatus hyphae, but not against resting conidia

    Stanislaw Schmidt;Lars Tramsen;Mitra Hanisch;Jean-Paul Latgé

  • Ex vivo expansion of highly purified NK cells for immunotherapy after haploidentical stem cell transplantation in children.

    U. Koehl;R. Esser;S. Zimmermann;T. Tonn

  • IL-2-driven regulation of NK cell receptors with regard to the distribution of CD16+ and CD16- subpopulations and in vivo influence after haploidentical NK cell infusion.

    Sabine Huenecke;Stefanie Yvonne Zimmermann;Stephan Kloess;Ruth Esser

Frequent Co-Authors

Thomas Klingebiel
Thomas Klingebiel Goethe University Frankfurt
Thomas Lehrnbecher
Thomas Lehrnbecher Goethe University Frankfurt
Peter Bader
Peter Bader Goethe University Frankfurt
Torsten Tonn
Torsten Tonn TU Dresden
Jakob Passweg
Jakob Passweg University Hospital of Basel
Axel Schambach
Axel Schambach Hannover Medical School
Jean-Paul Latgé
Jean-Paul Latgé University of Crete
Dieter Hoelzer
Dieter Hoelzer Goethe University Frankfurt
Antoine Toubert
Antoine Toubert Université Paris Cité
Arnold Ganser
Arnold Ganser Hannover Medical School

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