What is he best known for?
The fields of study he is best known for:
Raymond J. MacDonald mainly focuses on Molecular biology, Cell biology, Gene, Transcription factor and PDX1.
He has included themes like genomic DNA, Gene expression, Complementary DNA, Pancreatic elastase and Regulation of gene expression in his Molecular biology study.
His Complementary DNA research is multidisciplinary, relying on both Restriction enzyme and DNA.
Raymond J. MacDonald studied Cell biology and Cellular differentiation that intersect with Internal medicine, Endocrinology, Pancreas and Cell type.
His Transcription factor study integrates concerns from other disciplines, such as Acinar cell and Notch signaling pathway.
His is involved in several facets of Biochemistry study, as is seen by his studies on Coenzyme A, Acid guanidinium thiocyanate-phenol-chloroform extraction and RNA.
His most cited work include:
- Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. (18452 citations)
- Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes (1458 citations)
- The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors (834 citations)
What are the main themes of his work throughout his whole career to date?
Raymond J. MacDonald mostly deals with Molecular biology, Pancreas, Cell biology, Gene and Gene expression.
Raymond J. MacDonald interconnects Enhancer, Transcription factor, Biochemistry, Complementary DNA and Messenger RNA in the investigation of issues within Molecular biology.
His work in Messenger RNA covers topics such as RNA which are related to areas like Protein biosynthesis.
His Pancreas research includes elements of Progenitor cell, Secretion and Cellular differentiation.
In his research, Homeobox and Foregut is intimately related to PDX1, which falls under the overarching field of Cell biology.
His Gene research focuses on Kallikrein and how it connects with Gene family.
He most often published in these fields:
- Molecular biology (50.00%)
- Pancreas (24.22%)
- Cell biology (24.22%)
What were the highlights of his more recent work (between 2008-2020)?
- Cell biology (24.22%)
- Pancreas (24.22%)
- Transcription factor (20.31%)
In recent papers he was focusing on the following fields of study:
Cell biology, Pancreas, Transcription factor, Endocrinology and Internal medicine are his primary areas of study.
His Cell biology study incorporates themes from Genetics, Embryonic stem cell, Regulation of gene expression, PDX1 and Transcription.
His studies in Pancreas integrate themes in fields like Progenitor cell, Stem cell, Molecular biology and Cellular differentiation.
His Molecular biology study integrates concerns from other disciplines, such as TFAM, Beta cell, Insulin and Mitochondrion.
His Transcription factor research is multidisciplinary, relying on both Chromatin, Endoplasmic reticulum and Gene expression.
The various areas that he examines in his Endocrinology study include Missense mutation, Enteroendocrine cell and Proband.
Between 2008 and 2020, his most popular works were:
- Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis (107 citations)
- The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma (84 citations)
- PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression. (83 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Pancreas, Molecular biology, Cell biology, Cellular differentiation and Transcription factor.
A component of his Pancreas study involves Endocrinology and Internal medicine.
The concepts of his Molecular biology study are interwoven with issues in Insulin, Islet, Respiratory chain, Mitochondrion and ATP synthase.
His Cell biology study combines topics in areas such as TFAM and Beta cell.
As a member of one scientific family, Raymond J. MacDonald mostly works in the field of Cellular differentiation, focusing on Acinar cell and, on occasion, Enteroendocrine cell and Liver receptor homolog-1.
His Transcription factor research is multidisciplinary, incorporating perspectives in Gene expression and Nervous system.
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