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D-Index & Metrics

Molecular Biology

D-Index
66
Citations
39261
World Ranking
1595
National Ranking
806

Research.com Recognitions

  • 1991 - Fellow of the Royal Society of Edinburgh
  • Fellow of the Geological Society of America
  • Fellow of the Geological Society of America

Overview

Raymond J. MacDonald is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research encompasses several fields and subfields of study primarily in medicine, biochemistry, genetics, and molecular biology.

The main fields of study MacDonald focuses on include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

More specific subfields within these disciplines include:

  • Surgery
  • Molecular Biology
  • Oncology
  • Cell Biology
  • Inorganic Chemistry

MacDonald's scientific contributions span several topics, notably in:

  • Pancreatic and Hepatic Oncology Research
  • Pancreatic function and diabetes
  • Pancreatitis Pathology and Treatment
  • Endoplasmic Reticulum Stress and Disease
  • Epigenetics and DNA Methylation
  • Radioactive element chemistry and processing
  • FOXO transcription factor regulation

Their published work appears in multiple frequent venues, reflecting the diversity of research interests:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Chemical Geology
  • PLoS ONE

Some notable recent papers authored or coauthored by MacDonald include:

  • "NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation" (2023, Nature Communications)
  • "NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and suppresses PDAC initiation" (2021, bioRxiv [Cold Spring Harbor Laboratory])
  • "Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics" (2020, Scientific Reports)
  • "Experimental synthesis of ThSiO4 by fluid-induced alteration of chevkinite-(Ce): Evidence for element mobility and variable crystal structure" (2024, Chemical Geology)
  • "Key transcriptional effectors of the pancreatic acinar phenotype and oncogenic transformation" (2023, PLoS ONE)

MacDonald collaborates regularly with several frequent coauthors, including:

  • Thomas M. Wilkie
  • Isidoro Cobo
  • Sumit Paliwal
  • Júlia Melià-Alomà
  • Ariadna Torres-Sanchez

Throughout their career, Raymond J. MacDonald has received recognition from scientific communities, such as being named a Fellow of the Royal Society of Edinburgh in 1991 and a Fellow of the Geological Society of America.

Best Publications

  • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

    John M. Chirgwin;Alan E. Przybyla;Raymond J. MacDonald;William J. Rutter

  • Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes

    Don W. Cleveland;Margaret A. Lopata;Raymond J. MacDonald;Nicholas J. Cowan

  • The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

    Yoshiya Kawaguchi;Bonnie Cooper;Maureen Gannon;Michael Ray

  • Isolation of RNA using guanidinium salts.

    Raymond J. MacDonald;Galvin H. Swift;Alan E. Przybyla;John M. Chirgwin

  • Signaling and transcriptional control of pancreatic organogenesis.

    Seung K Kim;Raymond J MacDonald

  • Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice.

    Galvin H. Swift;Robert E. Hammer;Raymond J. MacDonald;Ralph L. Brinster

  • Experimental control of pancreatic development and maintenance.

    Andrew M. Holland;Michael A. Hale;Hideaki Kagami;Hideaki Kagami;Robert E. Hammer

  • Ptf1a determines horizontal and amacrine cell fates during mouse retinal development

    Yoshio Fujitani;Shuko Fujitani;Shuko Fujitani;Huijun Luo;Feng Qiu

  • Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice.

    David M. Ornitz;Richard D. Palmiter;Robert E. Hammer;Ralph L. Brinster

  • Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas

    Farzad Esni;Bidyut Ghosh;Andrew V. Biankin;John W. Lin

  • Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn

    Stacey M. Glasgow;R. Michael Henke;Raymond J. MacDonald;Christopher V. E. Wright

  • PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L.

    Thomas M. Beres;Thomas M. Beres;Toshihiko Masui;Galvin H. Swift;Ling Shi;Ling Shi

  • Structure of two related rat pancreatic trypsin genes.

    C. S. Craik;Qui-Lim Choo;G. H. Swift;C. Quinto

  • An Endocrine-Exocrine Switch in the Activity of the Pancreatic Homeodomain Protein PDX1 through Formation of a Trimeric Complex with PBX1b and MRG1 (MEIS2)

    Galvin H. Swift;Ying Liu;Scott D. Rose;Larry J. Bischof

  • Identification and characterization of cDNA clones specific for cholesterol side-chain cleavage cytochrome P-450

    Maliyakal E. John;Manorama C. John;Patricia Ashley;Raymond J. MacDonald

  • Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex.

    Toshihiko Masui;Qiaoming Long;Thomas M. Beres;Thomas M. Beres;Mark A. Magnuson

  • Conditional Expression Demonstrates the Role of the Homeodomain Transcription Factor Pdx1 in Maintenance and Regeneration of β-Cells in the Adult Pancreas

    Andrew M. Holland;L. Jorge Góñez;Gaetano Naselli;Raymond J. MacDonald

  • Two similar but nonallelic rat pancreatic trypsinogens. Nucleotide sequences of the cloned cDNAs.

    Raymond J MacDonald;S. J. Stary;Galvin H Swift

  • Molecular biology of tissue kallikrein.

    R J MacDonald;H S Margolius;E G Erdös

  • Molecular cloning of 3-hydroxy-3-methylglutaryl coenzyme a reductase and evidence for regulation of its mRNA

    Daniel J. Chin;Kenneth L. Luskey;Jerry R. Faust;Raymond J. MacDonald

Frequent Co-Authors

William J. Rutter
William J. Rutter University of California, San Francisco
Christopher V.E. Wright
Christopher V.E. Wright Vanderbilt University
Raymond Pictet
Raymond Pictet Université Paris Cité
Robert E. Hammer
Robert E. Hammer The University of Texas Southwestern Medical Center
Jane E. Johnson
Jane E. Johnson The University of Texas Southwestern Medical Center
Mark A. Magnuson
Mark A. Magnuson Vanderbilt University
Ralph L. Brinster
Ralph L. Brinster University of Pennsylvania
David Meredith
David Meredith Brigham and Women's Hospital
Charles S. Craik
Charles S. Craik University of California, San Francisco
Francisco X. Real
Francisco X. Real Pompeu Fabra University

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