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Genetics

D-Index
74
Citations
16405
World Ranking
1982
National Ranking
144

Overview

Boris Fehse is affiliated with Universität Hamburg in Germany, contributing extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans across various subfields including Molecular Biology, Genetics, Oncology, Immunology, and Hematology.

The scientist's work focuses on several key topics such as:

  • CAR-T cell therapy research
  • Virus-based gene therapy research
  • CRISPR and Genetic Engineering
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Viral Infectious Diseases and Gene Expression in Insects
  • Immune Cell Function and Interaction
  • Acute Myeloid Leukemia Research

Recent notable publications by Boris Fehse include:

  • CAR-HEMATOTOX: a model for CAR T-cell-related hematologic toxicity in relapsed/refractory large B-cell lymphoma (2021), published in Blood
  • Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia (2021), published in Blood
  • CD19-targeted chimeric antigen receptor T cell therapy in two patients with multiple sclerosis (2024), published in Med
  • Development of CAR-T cell therapies for multiple myeloma (2020), published in Leukemia
  • Overcoming the delivery problem for therapeutic genome editing: Current status and perspective of non-viral methods (2020), published in Biomaterials

Boris Fehse has collaborated frequently with several researchers, including:

  • Kristoffer Riecken (39 joint publications)
  • Anita Badbaran (24 joint publications)
  • Nicolaus Kröger (21 joint publications)
  • Francis Ayuk (19 joint publications)
  • Nico Gagelmann (16 joint publications)

Their work has been repeatedly published in venues such as Blood, Cancers, Leukemia, Gene Therapy, and bioRxiv (Cold Spring Harbor Laboratory), with Blood being the most frequent venue for publication.

In addition to research articles, Boris Fehse has authored a book titled Anwendung des Genome Editing in der somatischen Gentherapie, published by Springer Nature in 2021.

Best Publications

  • Murine leukemia induced by retroviral gene marking.

    Zhixiong Li;Zhixiong Li;Jochen Düllmann;Bernd Schiedlmeier;Manfred Schmidt

  • Side effects of retroviral gene transfer into hematopoietic stem cells

    Christopher Baum;Jochen Düllmann;Zhixiong Li;Boris Fehse

  • A Multicolor Panel of Novel Lentiviral “Gene Ontology” (LeGO) Vectors for Functional Gene Analysis

    Kristoffer Weber;Udo Bartsch;Carol Stocking;Boris Fehse

  • Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors.

    Christopher Baum;Olga Kustikova;Ute Modlich;Zhixiong Li

  • CAR-HEMATOTOX: A model for CAR T-cell related hematological toxicity in relapsed/refractory large B-cell lymphoma.

    Kai Rejeski;Ariel Perez Perez;Pierre Sesques;Eva Hoster

  • Clonal Dominance of Hematopoietic Stem Cells Triggered by Retroviral Gene Marking

    Olga Kustikova;Boris Fehse;Ute Modlich;Min Yang

  • Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma.

    Nicolaus Kröger;Rainer Schwerdtfeger;Michael Kiehl;Herbert Gottfried Sayer

  • Chance or necessity? Insertional mutagenesis in gene therapy and its consequences

    Christopher Baum;Christof von Kalle;Frank J.T Staal;Zhixiong Li

  • Insights in ChAdOx1 nCov-19 Vaccine-induced Immune Thrombotic Thrombocytopenia (VITT).

    Andreas Greinacher;Kathleen Selleng;Raghavendra Palankar;Jan Wesche

  • Unrelated stem cell transplantation in multiple myeloma after a reduced-intensity conditioning with pretransplantation antithymocyte globulin is highly effective with low transplantation-related mortality

    Nicolaus Kröger;Herbert Gottfried Sayer;Rainer Schwerdtfeger;Michael Kiehl

  • Liver-specific gene expression in cultured human hematopoietic stem cells.

    Henning C. Fiegel;Michael V. Lioznov;Lourdes Cortes-Dericks;Claudia Lange

  • Resistance of mature T cells to oncogene transformation.

    Sebastian Newrzela;Kerstin Cornils;Zhixiong Li;Christopher Baum

  • Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma

    Isabel Ben-Batalla;Alexander Schultze;Mark Wroblewski;Robert Erdmann

  • Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis

    Ute Modlich;Olga S Kustikova;Manfred Schmidt;Cornelia Rudolph

  • Dose finding with retroviral vectors: correlation of retroviral vector copy numbers in single cells with gene transfer efficiency in a cell population

    Olga S Kustikova;Anke Wahlers;Klaus Kuhlcke;Birgit Stahle

  • Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells

    M Michaelis;F Rothweiler;S Barth;J Cinatl

  • RGB marking facilitates multicolor clonal cell tracking

    Kristoffer Weber;Michael Thomaschewski;Michael Warlich;Tassilo Volz

  • Monitoring of the JAK2-V617F mutation by highly sensitive quantitative real-time PCR after allogeneic stem cell transplantation in patients with myelofibrosis.

    Nicolaus Kröger;Anita Badbaran;Ernst Holler;Joachim Hahn

  • TALEN-mediated editing of endogenous T-cell receptors facilitates efficient reprogramming of T lymphocytes by lentiviral gene transfer

    B Berdien;U Mock;D Atanackovic;B Fehse

  • Resistance of mature T cells to oncogene transformation. Commentary

    Utpal P. Dave;Sebastian Newrzela;Kerstin Cornils;Zhixiong Li

Frequent Co-Authors

Axel R. Zander
Axel R. Zander Huntsman Cancer Institute
Nicolaus Kröger
Nicolaus Kröger Universität Hamburg
Christopher Baum
Christopher Baum Charité - University Medicine Berlin
Carsten Bokemeyer
Carsten Bokemeyer Universität Hamburg
Axel Schambach
Axel Schambach Hannover Medical School
Wolfram Ostertag
Wolfram Ostertag Universität Hamburg
Brigitte Schlegelberger
Brigitte Schlegelberger Hannover Medical School
Arnold Ganser
Arnold Ganser Hannover Medical School
Klaus Pantel
Klaus Pantel Universität Hamburg
Dorothee von Laer
Dorothee von Laer Innsbruck Medical University

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