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Alexander Scheffold

Alexander Scheffold

D-Index & Metrics

Immunology

D-Index
66
Citations
16106
World Ranking
2758
National Ranking
182

Overview

Alexander Scheffold is affiliated with Kiel University in Germany. Their research primarily spans Medicine and Immunology and Microbiology, with a focus that includes Immunology, Infectious Diseases, Molecular Biology, Genetics, and Neurology.

Their body of work addresses several significant topics, among which are:

  • SARS-CoV-2 and COVID-19 Research
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • COVID-19 Clinical Research Studies
  • Vaccines and Immunoinformatics Approaches
  • Antifungal Resistance and Susceptibility
  • CAR-T Cell Therapy Research

Alexander Scheffold has published numerous papers in notable venues. Frequent publication venues include:

  • Immunity
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Crohn's and Colitis
  • Current Opinion in Microbiology
  • European Journal of Immunology

Recent papers by Alexander Scheffold include:

  • "Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials" (2020) published in The Lancet
  • "Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19" (2020) published in Immunity
  • "Low-Avidity CD4+ T Cell Responses to SARS-CoV-2 in Unexposed Individuals and Humans with Severe COVID-19" (2020) published in Immunity
  • "Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn's disease" (2023) published in Nature Medicine
  • "A novel unconventional T cell population enriched in Crohn's disease" (2022) published in Gut

The scientist has collaborated with several frequent co-authors, including:

  • Petra Bächer
  • Elisa Rosati
  • André Franke
  • Carina Saggau
  • Kristina Koop

Best Publications

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis

  • P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues

    Frank Austrup;Dietmar Vestweber;Eric Borges;Max Löhning

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Interleukin-2 is essential for CD4+CD25+ regulatory T cell function.

    Maurus de la Rosa;Sascha Rutz;Heike Dorninger;Alexander Scheffold

  • Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells

    Jochen Huehn;Kerstin Siegmund;Joachim C.U. Lehmann;Christiane Siewert

  • Expression of the integrin αEβ7 identifies unique subsets of CD25+ as well as CD25− regulatory T cells

    Joachim Lehmann;Jochen Huehn;Maurus de la Rosa;Frank Maszyna

  • Direct access to CD4 + T cells specific for defined antigens according to CD154 expression

    Marco Frentsch;Olga Arbach;Dennis Kirchhoff;Beate Moewes

  • Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans.

    Petra Bacher;Thordis Hohnstein;Eva Beerbaum;Marie Röcker

  • Rapid glucocorticoid effects on immune cells.

    Frank Buttgereit;Alexander Scheffold

  • Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.

    Birgit Sawitzki;Paul N Harden;Petra Reinke;Aurélie Moreau

  • MIP-1α, MIP-1β, RANTES, and ATAC/lymphotactin function together with IFN-γ as type 1 cytokines

    Brigitte G. Dorner;Alexander Scheffold;Michael S. Rolph;Martin B. Huser

  • Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.

    Joana P. Bernardes;Neha Mishra;Florian Tran;Thomas Bahmer

  • T-CELL EPITOPE MAPPING BY FLOW CYTOMETRY

    Florian Kern;Ingolf Pascal Surel;Carsten Brock;Bernd Freistedt

  • Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans.

    Petra Bacher;Frederik Heinrich;Ulrik Stervbo;Mikalai Nienen

  • CD14+CD34low Cells With Stem Cell Phenotypic and Functional Features Are the Major Source of Circulating Endothelial Progenitors

    Paola Romagnani;Francesco Annunziato;Francesco Liotta;Elena Lazzeri

  • Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments

    Dorothea Busse;Maurus de la Rosa;Kirstin Hobiger;Kevin Thurley

  • Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo.

    Kerstin Siegmund;Markus Feuerer;Christiane Siewert;Saeed Ghani

  • How αβ T cells deal with induced TCRα ablation

    Bojan Polic;Desiree Kunkel;Alexander Scheffold;Klaus Rajewsky

  • Low-Avidity CD4 + T Cell Responses to SARS-CoV-2 in Unexposed Individuals and Humans with Severe COVID-19.

    Petra Bacher;Elisa Rosati;Daniela Esser;Gabriela Rios Martini

  • Membrane glucocorticoid receptors (mGCR) are expressed in normal human peripheral blood mononuclear cells and up-regulated after in vitro stimulation and in patients with rheumatoid arthritis

    Burkhard Bartholome;Cornelia M. Spies;Timo Gaber;Sebastian Schuchmann

  • Antigen-Reactive T Cell Enrichment for Direct, High-Resolution Analysis of the Human Naive and Memory Th Cell Repertoire

    Petra Bacher;Christian Schink;Janka Teutschbein;Olaf Kniemeyer

  • Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry.

    Saskia J. A. M. Santegoets;Eveline M. Dijkgraaf;Alessandra Battaglia;Philipp Beckhove

Frequent Co-Authors

Andreas Radbruch
Andreas Radbruch German Rheumatism Research Centre
Markus M. Heimesaat
Markus M. Heimesaat Charité - University Medicine Berlin
Anja A. Kühl
Anja A. Kühl Humboldt-Universität zu Berlin
Richard A. Kroczek
Richard A. Kroczek Robert Koch Institute
Stefan Bereswill
Stefan Bereswill Charité - University Medicine Berlin
Jörg-Dieter Schulzke
Jörg-Dieter Schulzke Charité - University Medicine Berlin
Britta Siegmund
Britta Siegmund Humboldt-Universität zu Berlin
Stefan H. E. Kaufmann
Stefan H. E. Kaufmann Max Planck Institute for Infection Biology
Martin Zeitz
Martin Zeitz Charité - University Medicine Berlin
Christoph Loddenkemper
Christoph Loddenkemper Charité - University Medicine Berlin

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