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Immunology

D-Index
53
Citations
12879
World Ranking
3951
National Ranking
1809

Overview

Roland Tisch is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily spans the fields of Immunology and Microbiology, as well as Medicine, with a significant focus on Immunology as a subfield. Additional subfields include Genetics, Oncology, Animal Science and Zoology, and Surgery.

The scientist's work involves several main topics including Immune Cell Function and Interaction, Diabetes and associated disorders, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, Animal Virus Infections Studies, Pancreatic function and diabetes, and CAR-T cell therapy research.

Roland Tisch has published extensively, with contributions appearing frequently in venues such as UNC Libraries, Advanced Materials, Frontiers in Immunology, Cell, and ACS Nano.

Recent papers by Tisch include:

  • Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines, 2021, Cell
  • Evolving Antibody Therapies for the Treatment of Type 1 Diabetes, 2021, Frontiers in Immunology
  • The Role of T Cell Receptor Signaling in the Development of Type 1 Diabetes, 2021, Frontiers in Immunology
  • In Vivo Bioengineering of Beta Cells with Immune Checkpoint Ligand as a Treatment for Early-Onset Type 1 Diabetes Mellitus, 2021, ACS Nano
  • A Multitrait Locus Regulates Sarbecovirus Pathogenesis, 2022, mBio

Roland Tisch has collaborated frequently with several coauthors, including Charles J. Kroger, Matthew Clark, Ke Qi, Ralph S. Baric, and Kin Man Au.

Best Publications

  • Insulin-Dependent Diabetes Mellitus

    Roland Michael Tisch;Hugh McDevitt

  • Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice

    Roland Tisch;Xiao Dong Yang;Steven M. Singer;Roland S. Liblau

  • B Lymphocytes Are Critical Antigen-Presenting Cells for the Initiation of T Cell-Mediated Autoimmune Diabetes in Nonobese Diabetic Mice

    David V. Serreze;Sara A. Fleming;Harold D. Chapman;Scott D. Richard

  • Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process.

    Xiao-Dong Yang;Roland Tisch;Steven M. Singer;Zhu A. Cao

  • A sequential model for peptide binding and transport by the transporters associated with antigen processing.

    Peter M. van Endert;Peter M. van Endert;Robert Tampé;Thomas H. Meyer;Roland Tisch

  • Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice

    Jean David Bouaziz;Koichi Yanaba;Guglielmo M. Venturi;Yaming Wang

  • CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice.

    Balaji Balasa;Troy Krahl;Gail Patstone;Jae Lee

  • Single cell analysis shows decreasing FoxP3 and TGFβ1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes

    Shannon M. Pop;Carmen P. Wong;Donna A. Culton;Stephen H. Clarke

  • Immunoregulation of Dendritic Cells

    Mark A Wallet;Pradip Sen;Roland Tisch

  • Apoptotic cells induce Mer tyrosine kinase–dependent blockade of NF-κB activation in dendritic cells

    Pradip Sen;Mark A. Wallet;Zuoan Yi;Yingsu Huang

  • B Lymphocyte Depletion by CD20 Monoclonal Antibody Prevents Diabetes in Nonobese Diabetic Mice despite Isotype-Specific Differences in FcγR Effector Functions

    Yan Xiu;Carmen P. Wong;Jean David Bouaziz;Yasuhito Hamaguchi

  • Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis.

    Roland S. Liblau;Roland Tisch;Kevan Shokat;Xiao Dong Yang

  • Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IκB kinase activity

    Sandip Bhattacharyya;Pradip Sen;Mark Wallet;Brian Long

  • Inhibition of insulitis and prevention of diabetes in nonobese diabetic mice by blocking L-selectin and very late antigen 4 adhesion receptors.

    Xiao Dong Yang;Nathan Karin;Roland Michael Tisch;Lawrence Steinman

  • The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors.

    Pablo A. Silveira;Ellis Johnson;Harold D. Chapman;Thi Bui

  • Induction of GAD65-specific regulatory T-cells inhibits ongoing autoimmune diabetes in nonobese diabetic mice.

    Roland Michael Tisch;Roland S. Liblau;Xiao Dong Yang;Pascale Liblau

  • Elevated NF-κB Activation in Nonobese Diabetic Mouse Dendritic Cells Results in Enhanced APC Function

    Brian Poligone;Donald J. Weaver;Pradip Sen;Albert S. Baldwin

  • Induction of Glutamic Acid Decarboxylase 65-Specific Th2 Cells and Suppression of Autoimmune Diabetes at Late Stages of Disease Is Epitope Dependent

    Roland Tisch;Bo Wang;David V. Serreze

  • Dendritic Cells from Nonobese Diabetic Mice Exhibit a Defect in NF-κB Regulation Due to a Hyperactive IκB Kinase

    Donald J. Weaver;Brian Poligone;Thi Bui;Ussama M. Abdel-Motal

  • Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression.

    Michael A. Brehm;Laurie L. Kenney;Michael V. Wiles;Benjamin E. Low

  • Antigen-Specific Mediated Suppression of β Cell Autoimmunity by Plasmid DNA Vaccination

    Roland Tisch;Bo Wang;Donald J. Weaver;Bo Liu

  • Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.

    Alexandra C. Walls;Marcos C. Miranda;Alexandra Schäfer;Minh N. Pham

  • MerTK is required for apoptotic cell–induced T cell tolerance

    Mark A. Wallet;Pradip Sen;Rafael R. Flores;Yaming Wang

  • Critical Roles of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand in Type 1 Diabetes

    Salah Eddine Lamhamedi-Cherradi;Shijun Zheng;Roland M. Tisch;Youhai H. Chen

Frequent Co-Authors

Jeffrey A. Frelinger
Jeffrey A. Frelinger University of Arizona
Hugh O. McDevitt
Hugh O. McDevitt Stanford University
Glenn K. Matsushima
Glenn K. Matsushima University of North Carolina at Chapel Hill
Albert S. Baldwin
Albert S. Baldwin University of North Carolina at Chapel Hill
H. Shelton Earp
H. Shelton Earp University of North Carolina at Chapel Hill
David V. Serreze
David V. Serreze The Jackson Laboratory
Roland S. Liblau
Roland S. Liblau Federal University of Toulouse Midi-Pyrénées
Thomas F. Tedder
Thomas F. Tedder Duke University
Leonard D. Shultz
Leonard D. Shultz Jackson Laboratory
Thomas B. Kepler
Thomas B. Kepler Boston University

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