H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 87 Citations 33,862 223 World Ranking 478 National Ranking 285
Medicine D-index 88 Citations 37,369 227 World Ranking 6474 National Ranking 3576

Research.com Recognitions

Awards & Achievements

2006 - AAI Lifetime Achievement Award, American Association of Immunologists

2006 - American Association of Immunologists Lifetime Achievement Award

1998 - Jessie Stevenson Kovalenko Medal, US National Academy of Sciences For his landmark discovery and identification of genes that control immune responsiveness, and for his subsequent elucidation of mechanisms of antigen recognition and induction of the immune response.

1994 - Fellow of the Royal Society, United Kingdom

1987 - Fellow of the American Association for the Advancement of Science (AAAS)

1987 - Fellow of the American Association for the Advancement of Science (AAAS)

1987 - Paul Ehrlich and Ludwig Darmstaedter Prize

1984 - Fellow of the American Academy of Arts and Sciences

1984 - Member of the National Academy of Medicine (NAM)

1977 - Member of the National Academy of Sciences

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Antigen

His primary areas of investigation include Immunology, Antigen, Molecular biology, T cell and Major histocompatibility complex. His Immunology research includes elements of Endocrinology and Internal medicine. Hugh O. McDevitt has researched Antigen in several fields, including Antibody, Gene and Immune system.

His Molecular biology study combines topics from a wide range of disciplines, such as Apoptosis, Regulation of gene expression, Kidney and Allergy. His work in T cell tackles topics such as Interleukin 2 which are related to areas like Transplant rejection, Cancer research and Interferon gamma. His study on Major histocompatibility complex is covered under Genetics.

His most cited work include:

  • Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation (2026 citations)
  • HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. (1829 citations)
  • Insulin-Dependent Diabetes Mellitus (1080 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Immunology, Antigen, Molecular biology, Major histocompatibility complex and Genetics. The study incorporates disciplines such as Internal medicine and Nod in addition to Immunology. His research on Antigen also deals with topics like

  • Immune system, which have a strong connection to Histocompatibility,
  • Antibody which intersects with area such as Immune response gene and Spleen.

His Molecular biology research is multidisciplinary, incorporating perspectives in Antiserum, Biochemistry, Complementary DNA, Epitope and Cytotoxic T cell. His work deals with themes such as Experimental autoimmune encephalomyelitis and Peptide sequence, which intersect with Major histocompatibility complex. His NOD mice study integrates concerns from other disciplines, such as Adoptive cell transfer, IL-2 receptor and Insulitis.

He most often published in these fields:

  • Immunology (48.02%)
  • Antigen (33.74%)
  • Molecular biology (30.70%)

What were the highlights of his more recent work (between 1996-2020)?

  • Immunology (48.02%)
  • NOD mice (10.03%)
  • Nod (7.60%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Immunology, NOD mice, Nod, T cell and Antigen. His Immunology study incorporates themes from Internal medicine and Type 1 diabetes. His NOD mice research is multidisciplinary, relying on both Adoptive cell transfer, Alpha interferon, Immune tolerance and Immunotherapy.

His work carried out in the field of T cell brings together such families of science as Interleukin 2, Cytokine and Molecular biology. In his research, Human leukocyte antigen, Allele, MHC class II and Major histocompatibility complex is intimately related to Epitope, which falls under the overarching field of Molecular biology. Antigen is a primary field of his research addressed under Genetics.

Between 1996 and 2020, his most popular works were:

  • Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation (2026 citations)
  • In Vitro–expanded Antigen-specific Regulatory T Cells Suppress Autoimmune Diabetes (1007 citations)
  • Chronic Tumor Necrosis Factor Alters T Cell Responses by Attenuating T Cell Receptor Signaling (259 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • DNA

His scientific interests lie mostly in Immunology, NOD mice, T cell, Nod and Tumor necrosis factor alpha. His is involved in several facets of Immunology study, as is seen by his studies on Autoimmunity and Autoimmune disease. His NOD mice research incorporates elements of Adoptive cell transfer, IL-2 receptor and Immune tolerance.

The various areas that Hugh O. McDevitt examines in his T cell study include Interleukin 2, Epitope, Antigen and Islet. Hugh O. McDevitt interconnects Internal medicine and T-cell receptor in the investigation of issues within Nod. As part of one scientific family, Hugh O. McDevitt deals mainly with the area of Allele, narrowing it down to issues related to the Reporter gene, and often Molecular biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus.

John A. Todd;John I. Bell;John I. Bell;Hugh O. McDevitt.
Nature (1987)

2969 Citations

Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation

Anthony G. Wilson;Julian A. Symons;Tarra L. McDowell;Hugh O. McDevitt.
Proceedings of the National Academy of Sciences of the United States of America (1997)

2830 Citations

Insulin-Dependent Diabetes Mellitus

Roland Michael Tisch;Hugh McDevitt.
Cell (1996)

1724 Citations

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases

Roland S. Liblau;Steven M. Singer;Hugh O. McDevitt.
Immunology Today (1995)

1664 Citations

In Vitro–expanded Antigen-specific Regulatory T Cells Suppress Autoimmune Diabetes

Qizhi Tang;Kammi J. Henriksen;Mingying Bi;Erik B. Finger.
Journal of Experimental Medicine (2004)

1543 Citations

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice

Roland Tisch;Xiao Dong Yang;Steven M. Singer;Roland S. Liblau.
Nature (1993)

1440 Citations

Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

Hans Acha-Orbea;Dennis J. Mitchell;Luika Timmermann;David C. Wraith.
Cell (1988)

1117 Citations

Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus.

Chaim O. Jacob;Zdenka Fronek;Gail D. Lewis;May Koo.
Proceedings of the National Academy of Sciences of the United States of America (1990)

916 Citations

Tumour necrosis factor-α in murine autoimmune 'lupus' nephritis

Chaim O. Jacob;Hugh O. McDevitt.
Nature (1988)

837 Citations

Genetic control of specific immune responses.

McDevitt Ho;Benacerraf B.
Advances in Immunology (1969)

774 Citations

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