2026 Brian C. Thomas: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	71	6538	6036	3046	2737	116	23863

Overview

Brian C. Thomas is affiliated with Metagenomi in the United States and has contributed to research primarily in the field of Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields, including Molecular Biology, Health, Toxicology and Mutagenesis, Analytical Chemistry, Genetics, and Paleontology.

Their main research topics include:

CRISPR and Genetic Engineering
RNA and protein synthesis mechanisms
Advanced biosensing and bioanalysis techniques
Mercury impact and mitigation studies
Analytical chemistry methods development
CAR-T cell therapy research
Virus-based gene therapy research

Brian C. Thomas has collaborated frequently with several researchers, including:

Daniela S. Aliaga Goltsman
Christopher T. Brown
Cristina N. Butterfield
Lisa Alexander
Audra E. Devoto

Their recent papers demonstrate a focus on CRISPR systems, genome editing, and microbial metabolism. Notable publications include:

"Compact Cas9d and HEARO enzymes for genome editing discovered from uncultivated microbes" (2022) published in Nature Communications
"Genome-Resolved Metagenomics and Detailed Geochemical Speciation Analyses Yield New Insights into Microbial Mercury Cycling in Geothermal Springs" (2020) published in Applied and Environmental Microbiology
"CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes" (2023) published in Nucleic Acids Research
"Novel Type V-A CRISPR Effectors Are Active Nucleases with Expanded Targeting Capabilities" (2020) published in The CRISPR Journal
"Novel CRISPR-Associated Gene-Editing Systems Discovered in Metagenomic Samples Enable Efficient and Specific Genome Engineering" (2023) published in The CRISPR Journal

Frequent publication venues for Brian C. Thomas include:

The CRISPR Journal
Nature Communications
bioRxiv (Cold Spring Harbor Laboratory)
Analytical Chemistry
Nucleic Acids Research

Best Publications

A new view of the tree of life

Laura A. Hug;Laura A. Hug;Brett J. Baker;Karthik Anantharaman;Christopher T. Brown

2282
Citations
Unusual biology across a group comprising more than 15% of domain Bacteria

Christopher T. Brown;Laura A. Hug;Brian C. Thomas;Itai Sharon

1328
Citations
Thousands of microbial genomes shed light on interconnected biogeochemical processes in an aquifer system

Karthik Anantharaman;Christopher T. Brown;Laura A. Hug;Itai Sharon

1199
Citations
Recovery of genomes from metagenomes via a dereplication, aggregation and scoring strategy.

Christian M. K. Sieber;Christian M. K. Sieber;Alexander J. Probst;Allison Sharrar;Brian C. Thomas

1177
Citations
Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated bacterial phyla.

Kelly C. Wrighton;Brian C. Thomas;Itai Sharon;Christopher S. Miller

715
Citations
Community genomic analyses constrain the distribution of metabolic traits across the Chloroflexi phylum and indicate roles in sediment carbon cycling

Laura A Hug;Cindy J Castelle;Kelly C Wrighton;Brian C Thomas

631
Citations
Community-wide analysis of microbial genome sequence signatures

Gregory J Dick;Gregory J Dick;Anders F Andersson;Anders F Andersson;Brett J Baker;Sheri L Simmons

626
Citations
Microbes in the neonatal intensive care unit resemble those found in the gut of premature infants

Brandon Brooks;Brian A Firek;Christopher S Miller;Christopher S Miller;Itai Sharon

601
Citations
Genomic Expansion of Domain Archaea Highlights Roles for Organisms from New Phyla in Anaerobic Carbon Cycling

Cindy J. Castelle;Kelly C. Wrighton;Brian C. Thomas;Laura A. Hug

594
Citations
New CRISPR–Cas systems from uncultivated microbes

David Burstein;Lucas B. Harrington;Steven C. Strutt;Alexander J. Probst

584
Citations
Gene-balanced duplications, like tetraploidy, provide predictable drive to increase morphological complexity

Michael Freeling;Brian C. Thomas

526
Citations
Time series community genomics analysis reveals rapid shifts in bacterial species, strains, and phage during infant gut colonization

Itai Sharon;Michael J. Morowitz;Brian C. Thomas;Elizabeth K. Costello

511
Citations
Following tetraploidy in an Arabidopsis ancestor, genes were removed preferentially from one homeolog leaving clusters enriched in dose-sensitive genes

Brian C. Thomas;Brent Pedersen;Michael Freeling

478
Citations
Diverse uncultivated ultra-small bacterial cells in groundwater

Birgit Luef;Kyle R. Frischkorn;Kyle R. Frischkorn;Kelly C. Wrighton;Kelly C. Wrighton;Hoi-Ying N. Holman

462
Citations
The human gut and groundwater harbor non-photosynthetic bacteria belonging to a new candidate phylum sibling to Cyanobacteria

Sara C Di Rienzi;Itai Sharon;Kelly C Wrighton;Omry Koren

398
Citations
Expanded diversity of microbial groups that shape the dissimilatory sulfur cycle.

Karthik Anantharaman;Karthik Anantharaman;Bela Hausmann;Sean P. Jungbluth;Sean P. Jungbluth;Rose S. Kantor

397
Citations
Measurement of bacterial replication rates in microbial communities

Christopher T Brown;Matthew R Olm;Brian C Thomas;Jillian F Banfield;Jillian F Banfield

389
Citations
EMIRGE: reconstruction of full-length ribosomal genes from microbial community short read sequencing data.

Christopher S Miller;Brett J Baker;Brett J Baker;Brian C Thomas;Steven W Singer;Steven W Singer

387
Citations
Novel soil bacteria possess diverse genes for secondary metabolite biosynthesis

Alexander Crits-Christoph;Spencer Diamond;Cristina N. Butterfield;Brian C. Thomas

377
Citations
Author response: The human gut and groundwater harbor non-photosynthetic bacteria belonging to a new candidate phylum sibling to Cyanobacteria

Sara C Di Rienzi;Itai Sharon;Kelly C Wrighton;Omry Koren

1
Citations